Abstract: The present invention provides a composite plate device for a thermal transpiration micropump apparatus. The provided composite plate device includes a substrate having a plurality of flow channels and a plurality of templates with closed sidewalls, wherein the plurality of flow channels allow fluid to flow therethrough and have a feature length larger than or equal to the mean free path length of the fluid. The provided composite plate device further includes a porous material that is filled in the plurality of templates of the substrate, wherein the porous material allows the fluid to flow therethrough and has an equivalent pore diameter smaller than or equal to the mean free path length of the fluid.

Abstract: An integrative microdialysis and chip-based electrophoresis system and analytical method using the same are disclosed. The system combines the microdialysis probe sampling technique and continuous pressure flow feeding coupled with chip-based electrophoresis analysis. It is capable of performing online sampling as well as rapid and continuous monitoring and analysis of biological samples. The system offers the advantages of real-time on-chip dye labeling, simple apparatus setup and easy operation.