Patents by Inventor Hsueh-Hsiao Wang

Hsueh-Hsiao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF GOLD NANOCLUSTERS IN TREATING HYPERCHOLESTEROLEMIA OR HYPERCHOLESTEROLEMIA-ASSOCIATED DISEASES
    Publication number: 20220192999
    Abstract: Disclosed herein is a novel use of a gold nanocluster for treating hypercholesterolemia or hypercholesterolemia-associated diseases, for example, atherosclerosis. According to embodiments of the present disclosure, the gold nanocluster has a particle size ranging from about 1 to 10 nm, and consists of, a gold nanocluster formed by a plurality of gold nanoparticles, and a plurality of DHLAs coated on the gold nanocluster.
    Type: Application
    Filed: May 7, 2019
    Publication date: June 23, 2022
    Applicants: GoldRed NanoBiotech CO., LTD.
    Inventors: Hung-I YEH, Yi-Nan LEE, Hong-Shong CHANG, Kuan-Jung LI, Wei-Chung LAI, Hsueh-Hsiao WANG
  • Method for treating inflammatory diseases
    Patent number: 11285172
    Abstract: Disclosed herein is a method for treating an inflammatory disease in a subject, including administering to the subject a therapeutically effective amount of a dihydrolipoic acid (DHLA) coated gold nanocluster about 0.1 to 20 nm in diameter. Also disclosed is a method for reducing the expression of a pro-inflammatory molecule in a cultured cell, including contacting the cultured cell with the said DHLA coated gold nanocluster. Still disclosed is a pharmaceutical composition that includes the present DHLA coated gold nanocluster. The pharmaceutical composition is useful for treating the inflammatory disease in the subject.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: March 29, 2022
    Assignees: MacKay Memorial Hospital, GoldRed NanoBiotech CO., LTD.
    Inventors: Hsueh-Hsiao Wang, Hung-I Yeh, Hong-Shong Chang
  • METHOD FOR TREATING INFLAMMATORY DISEASES
    Publication number: 20200268792
    Abstract: Disclosed herein is a method for treating an inflammatory disease in a subject, including administering to the subject a therapeutically effective amount of a dihydrolipoic acid (DHLA) coated gold nanocluster about 0.1 to 20 nm in diameter. Also disclosed is a method for reducing the expression of a pro-inflammatory molecule in a cultured cell, including contacting the cultured cell with the said DHLA coated gold nanocluster. Still disclosed is a pharmaceutical composition that includes the present DHLA coated gold nanocluster. The pharmaceutical composition is useful for treating the inflammatory disease in the subject.
    Type: Application
    Filed: February 25, 2020
    Publication date: August 27, 2020
    Applicants: MacKay Memorial Hospital, GoldRed NanoBiotech CO., LTD.
    Inventors: Hsueh-Hsiao WANG, Hung-I YEH, Hong-Shong CHANG
  • Use of gold nanoclusters in ameliorating oxidate stress and/or aging
    Patent number: 9101672
    Abstract: Disclosed herein is the novel use of a gold nanocluser for ameliorating oxidative stress and/or aging of a cultured cell or a subject having an oxidative stress and/or aging condition mediated by a vascular factor. The gold nanocluster has a particle size ranging from about 0.1 to 20 nm, and preferably is dihydrolipoic acid (DHLA) coated gold nanocluster.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: August 11, 2015
    Assignees: MACKAY MEMORIAL HOSPITAL, CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Hung-I Yeh, Walter H. Chang, Cheng-An Lin, Hsueh-Hsiao Wang
  • Use of Gold Nanoclusters in Ameliorating Oxidate Stress and/or Aging
    Publication number: 20130052270
    Abstract: Disclosed herein is the novel use of a gold nanocluser for ameliorating oxidative stress and/or aging of a cultured cell or a subject having an oxidative stress and/or aging condition mediated by a vascular factor. The gold nanocluster has a particle size ranging from about 0.1 to 20 nm, and preferably is dihydrolipoic acid (DHLA) coated gold nanocluster.
    Type: Application
    Filed: August 26, 2011
    Publication date: February 28, 2013
    Applicants: CHUNG YUAN CHRISTIAN UNIVERSITY, MACKAY MEMORIAL HOSPITAL
    Inventors: Hung-I Yeh, Walter H. Chang, Cheng-An Lin, Hsueh-Hsiao Wang