Abstract: The present invention provides a method for preparing a reconstituted apolipoprotein B lipoparticle and the method comprises steps of (a) dissolving an apolipoprotein B and a lipid in a first buffer containing 2 M to 8 M urea and 1 wt % to 15 wt % amphiphilic compounds to form a mixture; and (b) dialyzing the mixture against a second buffer containing 0 M to 2M urea and 0 wt % to 0.5 wt % amphiphilic compounds for 1 to several times for lowering concentrations of the urea and the amphiphilic compounds in the mixture. The present invention further provides an apolipoprotein B lipoparticle and a use for the production of an apolipoprotein B lipoparticle used for delivering a hydrophobic substance.

Abstract: The present invention provides a method for preparing a reconstituted apolipoprotein B lipoparticle and the method comprises steps of (a) dissolving an apolipoprotein B and a lipid in a first buffer containing 2 M to 8 M urea and 1 wt % to 15 wt % amphiphilic compounds to form a mixture; and (b) dialyzing the mixture against a second buffer containing 0 M to 2M urea and 0 wt % to 0.5 wt % amphiphilic compounds for 1 to several times for lowering concentrations of the urea and the amphiphilic compounds in the mixture. The present invention further provides an apolipoprotein B lipoparticle and a use for the production of an apolipoprotein B lipoparticle used for delivering a hydrophobic substance.

Abstract: A method for producing a silicon-containing zirconia calcined body includes wet mixing a mixture to obtain a mixed slurry, with the mixture including a silicon-containing zirconia powder, a sodium carbonate powder, a tetraethoxysilane, and an adhesive; drying the mixed slurry to obtain a caked mass; grinding and sieving the caked mass to obtain a mixed powder; pressurizing and shaping the mixed powder to obtain a blank; and calcining the blank in an environment at 900-1200° C. to obtain a silicon-containing zirconia calcined body. The silicon-containing zirconia calcined body can be sintered at 1415-1450° C. into a silicon-containing zirconia sintered body, with a shrinkage ratio during sintering the silicon-containing zirconia calcined body into the silicon-containing zirconia sintered body being 22-31%.

Abstract: A method for producing a silicon-containing zirconia calcined body includes wet mixing a mixture to obtain a mixed slurry, with the mixture including a silicon-containing zirconia powder, a sodium carbonate powder, a tetraethoxysilane, and an adhesive; drying the mixed slurry to obtain a caked mass; grinding and sieving the caked mass to obtain a mixed powder; pressurizing and shaping the mixed powder to obtain a blank; and calcining the blank in an environment at 900-1200° C. to obtain a silicon-containing zirconia calcined body. The silicon-containing zirconia calcined body can be sintered at 1415-1450° C. into a silicon-containing zirconia sintered body, with a shrinkage ratio during sintering the silicon-containing zirconia calcined body into the silicon-containing zirconia sintered body being 22-31%.

Abstract: The present invention provides a method for preparing a reconstituted apolipoprotein B lipoparticle and the method comprises steps of (a) dissolving an apolipoprotein B and a lipid in a first buffer containing 2 M to 8 M urea and 1 wt % to 15 wt % amphiphilic compounds to form a mixture; and (b) dialyzing the mixture against a second buffer containing 0 M to 2M urea and 0 wt % to 0.5 wt % amphiphilic compounds for 1 to several times for lowering concentrations of the urea and the amphiphilic compounds in the mixture. The present invention further provides an apolipoprotein B lipoparticle and a use for the production of an apolipoprotein B lipoparticle used for delivering a hydrophobic substance.