Abstract: Provided are a fibroblast activation protein inhibitor (FAPI) dimer compound, an FAPI dimer-based positron emission tomography (PET) imaging agent for tumor diagnosis, and a preparation method and use thereof. An amphiphilic polyethylene glycol (PEG) chain and a dimerized structure of FAPI in the FAPI dimer compound with a structure shown in formula I can improve the in vivo kinetic properties of the compound and prolong a residence time of the compound in a tumor, thereby improving the uptake and imaging effects in the tumor. The accurate tumor diagnosis can be achieved by labeling the FAPI dimer compound with a diagnostic nuclide (68Ga), which has promising application prospects in PET imaging for diagnosis and in the preparation of a therapeutic nuclide (such as 177Lu or 90Y)-labeled drug for treating a FAP-?-expressing tumor.

Abstract: An electric paper tray includes a base, a paper holding element pivotally mounted to at least one side of the base, a power unit arranged at the base, and a lifting module connected between the paper holding element and the power unit. The lifting module is movably mounted under the paper holding element. When the lifting module is driven by the power unit to move to a first position, with respect to the base, the lifting module drives the paper holding element to make the paper holding element rotate to a closed position, when the lifting module is driven by the power unit to move to a second position, with respect to the base, the lifting module drives the paper holding element to make the paper holding element rotate to an opened position.

Abstract: A touch panel includes a substrate, a raised structure, a touch sensing electrode layer, and a peripheral circuit layer. The substrate has a visible region and a border region surrounding the visible region. The raised structure is disposed on the substrate and located in the border region, in which the raised structure and the substrate constitute a step area. The touch sensing electrode layer is disposed in the visible region and partially extends to the border region to cross over the raised structure and cover the step area. The peripheral circuit layer is disposed in the border region, and overlaps the touch sensing electrode layer at least on the raised structure and the step area.

Abstract: A feeding roller structure includes a fastening frame, a transmission component, a transmission roller and a floating coupler. The transmission component is assembled in the fastening frame. The transmission component includes a drive shaft mounted on two sides of the fastening frame. The transmission roller is concentrically arranged around the drive shaft. The floating coupler is mounted to the fastening frame. The floating coupler is coupled between the drive shaft and the transmission roller. Two opposite ends of the floating coupler are adjacent to and spaced from the two sides of the fastening frame to form two gaps. Each gap is formed between one end of the floating coupler and one side of the fastening frame. The two gaps limit an angular displacement of the floating coupler.

Abstract: Disclosed herein is a novel single nucleotide polymorphism (SNP) in HLA-B*15:02 that can be used as a biomarker for carbamazepine-induced severe adverse skin reactions in Asians. Also provided herein are methods and reagents for assessing the specific SNP, and applying the SNP in predicting an increased risk of carbamazepine-induced severe adverse skin reactions.

Abstract: A touch panel includes a substrate, a peripheral circuit layer, and a touch sensing electrode layer. The substrate has a visible region and a border region surrounding the visible region. The peripheral circuit layer is disposed on the substrate and located in the border region, and has at least one concave portion, in which the concave portion is located on a surface of the peripheral circuit layer facing away from the substrate. The touch sensing electrode layer is disposed in the visible region and partially extends to the border region to at least cover the concave portion, in which the touch sensing electrode layer has at least one entering portion extending into the concave portion.

Abstract: A scanner includes a scanning module. The scanning module has a scan channel and a scanning glass. A lower surface of the scanner is defined as a bottom wall of the scan channel. The scanning glass is positioned above the scan channel. A bottom surface of the scanning glass is defined as a top wall of the scan channel. The lower surface of the scanner has an upstream turn connected between an upstream section and a middle section of the lower surface of the scanner, the middle section of the lower surface of the scanner is parallel with the bottom surface of the scanning glass.

Abstract: A touch panel includes a substrate, a peripheral circuit layer, and a touch sensing electrode layer. The substrate has a visible region and a border region surrounding the visible region. The peripheral circuit layer is disposed on the substrate and located in the border region, and has at least one concave portion, in which the concave portion is located on a surface of the peripheral circuit layer facing away from the substrate. The touch sensing electrode layer is disposed in the visible region and partially extends to the border region to at least cover the concave portion, in which the touch sensing electrode layer has at least one entering portion extending into the concave portion.

Abstract: A touch panel includes a substrate, a raised structure, a touch sensing electrode layer, and a peripheral circuit layer. The substrate has a visible region and a border region surrounding the visible region. The raised structure is disposed on the substrate and located in the border region, in which the raised structure and the substrate constitute a step area. The touch sensing electrode layer is disposed in the visible region and partially extends to the border region to cross over the raised structure and cover the step area. The peripheral circuit layer is disposed in the border region, and overlaps the touch sensing electrode layer at least on the raised structure and the step area.

Abstract: A touch panel includes a substrate, a peripheral trace, and a touch sensing electrode. The substrate has a visible area, a peripheral area, a bending area, and a non-bending area. The peripheral trace is disposed on the peripheral area. The touch sensing electrode is disposed on the visible area and has a first portion disposed on the bending area and a second portion disposed on the non-bending area. The touch sensing electrode has a mesh pattern interlaced by a plurality of thin lines. The peripheral trace and the touch sensing electrode each includes a plurality of conductive nanostructures and a film layer added onto the conductive nanostructures, and an interface between each of the conductive nanostructures and the film layer that are in the peripheral trace and in the second portion of the touch sensing electrode substantially has a covering structure.

Abstract: A touch panel includes a substrate, a peripheral trace, and a touch sensing electrode. The substrate has a visible area, a peripheral area, a bending area, and a non-bending area. The peripheral trace is disposed on the peripheral area. The touch sensing electrode is disposed on the visible area and has a first portion disposed on the bending area and a second portion disposed on the non-bending area. The touch sensing electrode has a mesh pattern interlaced by a plurality of thin lines. The peripheral trace and the touch sensing electrode each includes a plurality of conductive nanostructures and a film layer added onto the conductive nanostructures, and an interface between each of the conductive nanostructures and the film layer that are in the peripheral trace and in the second portion of the touch sensing electrode substantially has a covering structure.

Abstract: An electric paper tray includes a base, a paper holding element pivotally mounted to at least one side of the base, a power unit arranged at the base, and a lifting module connected between the paper holding element and the power unit. The lifting module is movably mounted under the paper holding element. When the lifting module is driven by the power unit to move to a first position, with respect to the base, the lifting module drives the paper holding element to make the paper holding element rotate to a closed position, when the lifting module is driven by the power unit to move to a second position, with respect to the base, the lifting module drives the paper holding element to make the paper holding element rotate to an opened position.

Abstract: A feeding roller structure includes a fastening frame, a transmission component, a transmission roller and a floating coupler. The transmission component is assembled in the fastening frame. The transmission component includes a drive shaft transversely pivoted to two sides of the fastening frame. The transmission roller is concentrically arranged around the drive shaft. The floating coupler is mounted to the fastening frame. The floating coupler is coupled between the drive shaft and the transmission roller. Two opposite ends of the floating coupler are adjacent to and spaced from the two sides of the fastening frame to form two gaps. Each gap is formed between one end of the floating coupler and one side of the fastening frame. The two gaps limit an angular displacement of the floating coupler.

Abstract: A scanner includes a scanning module. The scanning module has a scan channel and a scanning glass. A lower surface of the scanner is defined as a bottom wall of the scan channel. The scanning glass is positioned above the scan channel. A bottom surface of the scanning glass is defined as a top wall of the scan channel. The lower surface of the scanner has an upstream turn connected between an upstream section and a middle section of the lower surface of the scanner, the middle section of the lower surface of the scanner is parallel with the bottom surface of the scanning glass.

Abstract: A multiple imputation (MI) based fuzzy clustering with visualization-aided MI validation that improves the accuracy and the stability of identified patterns, generally the structure of HD data with missing values.

Abstract: Disclosed herein is a novel single nucleotide polymorphism (SNP) in HLA-B*15:02 that can be used as a biomarker for carbamazepine-induced severe adverse skin reactions in Asians. Also provided herein are methods and reagents for assessing the specific SNP, and applying the SNP in predicting an increased risk of carbamazepine-induced severe adverse skin reactions.

Abstract: A lighting apparatus includes an outer housing surrounding a longitudinal axis and made of light-transmissive material, a supporting mount provided within the outer housing, a pair of end caps coupled to opposite ends of the outer housing and supporting mount to define a watertight internal chamber, and a plurality of lighting devices provided on a surface of the supporting mount inside the internal chamber. Each of the lighting devices includes a circuit component and a lighting module detachably mounted to the circuit component.

Abstract: Disclosed herein is a novel single nucleotide polymorphism (SNP) in HLA-B*15:02 that can be used as a biomarker for carbamazepine-induced severe adverse skin reactions in Asians. Also provided herein are methods and reagents for assessing the specific SNP, and applying the SNP in predicting an increased risk of carbamazepine-induced severe adverse skin reactions.

Abstract: A modular underwater lighting apparatus includes an outer housing, a supporting mount, and a plurality of lighting devices. The outer housing includes an outer surrounding wall extending to surround a longitudinal axis and made of a light-transmissive material. The supporting mount is mounted inside the outer housing. The lighting devices are separately mounted on the supporting mount. Each of the lighting devices includes a circuit component and a lighting module which is detachably mounted to the circuit component.

Abstract: A method for processing a voice instruction received at a plurality of devices is provided. The method includes creating a group list including the plurality of devices, receiving information regarding the voice instruction from each device in the group list based on the plurality of devices receiving the voice instruction from a user, selecting at least one device in the group list by processing the received information, and causing the selected at least one device to perform an operation corresponding to the voice instruction.