Abstract: Provided is a semiconductor device including a substrate, a channel layer, a gate structure, a first doped region, a second doped region, a third doped region and a channel cap layer. The channel layer is located on the substrate. The channel layer has a trench. The gate structure is disposed in the trench. The first doped region and the second doped region are located in the channel layer on two sides of the gate structure. The third doped region is located in the substrate below the channel layer. The channel cap layer is located between the gate structure and the first doped region, between the gate structure and the second doped region, and between the gate structure and the channel layer. An energy band gap of the channel cap layer is larger than an energy band gap of the channel layer.

Abstract: An electrical connection structure is provided. The electrical connection structure includes a through hole, a first pad, a second pad and a conductive bridge. The through hole has a first end and a second end. The first pad at least partially surrounds the first end of the through hole and is electrically connected to a first circuit. The second pad is located at the second end of the through hole and is electrically connected to a second circuit. The conductive bridge is connected to the first pad and second pad through the through hole, thereby making the first and second circuits electrically connected to each other.

Abstract: Various embodiments of the present disclosure are directed towards an image sensor, and a method for forming the image sensor, in which an inter-pixel trench isolation structure is defined by a low-transmission layer. In some embodiments, the image sensor comprises an array of pixels and the inter-pixel trench isolation structure. The array of pixels is on a substrate, and the pixels of the array comprise individual photodetectors in the substrate. The inter-pixel trench isolation structure is in the substrate. Further, the inter-pixel trench isolation structure extends along boundaries of the pixels, and individually surrounds the photodetectors, to separate the photodetectors from each other. The inter-pixel trench isolation structure is defined by a low-transmission layer with low transmission for incident radiation, such that the inter-pixel trench isolation structure has low transmission for incident radiation.

Abstract: Various embodiments of the present disclosure are directed towards an image sensor, and a method for forming the image sensor, in which an inter-pixel trench isolation structure is defined by a low-transmission layer. In some embodiments, the image sensor comprises an array of pixels and the inter-pixel trench isolation structure. The array of pixels is on a substrate, and the pixels of the array comprise individual photodetectors in the substrate. The inter-pixel trench isolation structure is in the substrate. Further, the inter-pixel trench isolation structure extends along boundaries of the pixels, and individually surrounds the photodetectors, to separate the photodetectors from each other. The inter-pixel trench isolation structure is defined by a low-transmission layer with low transmission for incident radiation, such that the inter-pixel trench isolation structure has low transmission for incident radiation.

Abstract: The invention described in the application relates to a panel of gene expression markers for patient with a tumor. The invention thus provides methods and compositions, e.g., kits, for evaluating gene expression levels of the markers and methods of using such gene expression levels to evaluate the likelihood of disease progression or response to chemotherapy or radiation therapy. Such information can be used in determining prognosis and treatment options for cancer patients.

Abstract: The present disclosure describes a semiconductor device that includes a first die bonded to a second die with interconnect structures in the first die. The first die includes a photodiode having first and second electrodes on a first side of a first dielectric layer, and first, second, and third interconnect structures in the first dielectric layer. The first and second interconnect structures are connected to the first and second electrodes, respectively. The second electrode has a polarity opposite to the first electrode. The second and third interconnect structures extend to a second side opposite to the first side of the first dielectric layer. The second die includes a second dielectric layer and a fourth interconnect structure in the second dielectric layer. The second dielectric layer is bonded to the second side of the first dielectric layer. The fourth interconnect structure connects the second and third interconnect structures.

Abstract: Various embodiments of the present disclosure are directed towards an image sensor, and a method for forming the image sensor, in which an inter-pixel trench isolation structure is defined by a low-transmission layer. In some embodiments, the image sensor comprises an array of pixels and the inter-pixel trench isolation structure. The array of pixels is on a substrate, and the pixels of the array comprise individual photodetectors in the substrate. The inter-pixel trench isolation structure is in the substrate. Further, the inter-pixel trench isolation structure extends along boundaries of the pixels, and individually surrounds the photodetectors, to separate the photodetectors from each other. The inter-pixel trench isolation structure is defined by a low-transmission layer with low transmission for incident radiation, such that the inter-pixel trench isolation structure has low transmission for incident radiation.

Abstract: A system, method and gateway are provided. The method is executed by a primary gateway, and includes obtaining status information from smart devices, a first portion of which belong to and communicate with the primary gateway using a first standard, and a second portion of which belong to and communicate with a secondary gateway using a second standard. The status information from the smart devices belonging to the secondary gateway is received from the secondary gateway, and the status information from the smart devices belonging to the primary gateway is received directly from the smart devices belonging to the primary gateway. A control instruction for controlling a second smart device is generated in response to status information from a first smart device complying with an interworking rule, where the first and second smart devices communicate using different standards. The control instruction is transmitted to the second smart device.

Abstract: The present disclosure provides a pharmaceutical composition of fused tricyclic gamma-amino acid derivatives and the use thereof. The pharmaceutical composition includes: (i) a compound having a structure represented by formula (I) or a pharmaceutically acceptable salt thereof, as an active material, in an amount of 1% to 45% by weight; (ii) optionally one or more fillers in an amount of 50% to 95% by weight; (iii) optionally one or more lubricating agents in an amount of 0.1% to 5.5% by weight; and the sum of weight percentages of the all components is 100%, wherein the pharmaceutically acceptable salt of the compound of formula (I) has a structure as follows.

Abstract: A system, method and gateway are provided. The method is executed by a primary gateway, and includes obtaining status information from smart devices, a first portion of which belong to and communicate with the primary gateway using a first standard, and a second portion of which belong to and communicate with a secondary gateway using a second standard. The status information from the smart devices belonging to the secondary gateway is received from the secondary gateway, and the status information from the smart devices belonging to the primary gateway is received directly from the smart devices belonging to the primary gateway. A control instruction for controlling a second smart device is generated in response to status information from a first smart device complying with an interworking rule, where the first and second smart devices communicate using different standards. The control instruction is transmitted to the second smart device.

Abstract: A tracking method for a video surveillance system includes: obtaining identification information for a first target object uploaded by a positioning system; obtaining time information and location information for the positioning system at the time the positioning system uploads the identification information; storing the identification information, the location information, and the time information in a preset database to obtain a storage result; and generating tracking information for the first target object according to the storage result.

Abstract: A gas detection module is provided with a convenient detection mechanism of the alcohol gas. The gas detection module may include a gas sensor and a detection circuit. The gas sensor includes a substrate, a gate, an insulating layer, an active layer, a source and a drain. The gate is disposed on the substrate. The insulating layer is disposed on the gate and the substrate. The active layer is disposed on the insulating layer. Each of the source and the drain is partially arranged on the active layer and extends to the insulating layer. The active layer is exposed from between the source and the drain. The detection circuit is electrically connected to the source of the gas sensor. Based on this, the deficiency of the conventional gas detection module can be overcome.

Abstract: The present invention provides for a library or an array of two or more nucleic acids encoding portions of genes selected from a set of 27 genes which are useful for predicting lung cancer survival, and a method for predicting a subject's overall survival (OS) from a lung cancer using two or more genes selected from the set of 27 genes.

Abstract: Provided are methods of producing gene expression profiles of subjects having cancer. In certain aspects, the methods include contacting a sample obtained from breast tumor tissue (e.g., breast tumor tissue of a Luminal A molecular subtype) with reagents for determining the expression levels of ZIC2, RGS16, SLC2A1, DDR2, PTPLAD1, CMTM8, and TROAP. In some aspects, the methods include contacting a RNA sample obtained from breast tumor tissue (e.g., breast tumor tissue of a Basal molecular subtype) with reagents for determining the expression levels of CXCL13, CRYBB2, ITSN1, PLA1A, LAMC2, RGS5, WWC3, TTLL7, ANAPC1, TSSC1, CFH, HAUS4, RAMP3, MED28, TSC22D3, LSM14A, and ASIP. Kits that find use, e.g., in practicing the methods of the present disclosure, are also provided.

Abstract: A tracking method for a video surveillance system includes: obtaining identification information for a first target object uploaded by a positioning system; obtaining time information and location information for the positioning system at the time the positioning system uploads the identification information; storing the identification information, the location information, and the time information in a preset database to obtain a storage result; and generating tracking information for the first target object according to the storage result.

Abstract: The present invention provides for a probiotic composition designed to enhance memory and/or reduce fear and/or pain of a host, the probiotic composition comprising viable or live cells of one or more of the family/order/strain selected from a group consisting of RF39, Lactobacillaceae, Bacteroidaceae, Lachnospiraceae, Anaeroplasmataceae, Ruminococcaceae, Clostridiales, Clostridiaceae, Rikenellaceae, Erysipelotrichaceae, Peptococcaceae, Turicibacteraceae, Deferribacteraceae, Cytophagaceae, Chitinophagaceae, Coriobacteriaceae, Bifidobacteriaceae, and S24.7. The present invention also provides for a method of enhancing memory and/or reducing fear and/or pain of a host, the method comprising: administering the probiotic composition to a host.

Abstract: A gas detection module is provided with a convenient detection mechanism of the alcohol gas. The gas detection module may include a gas sensor and a detection circuit. The gas sensor includes a substrate, a gate, an insulating layer, an active layer, a source and a drain. The gate is disposed on the substrate. The insulating layer is disposed on the gate and the substrate. The active layer is disposed on the insulating layer. Each of the source and the drain is partially arranged on the active layer and extends to the insulating layer. The active layer is exposed from between the source and the drain. The detection circuit is electrically connected to the source of the gas sensor. Based on this, the deficiency of the conventional gas detection module can be overcome.

Abstract: The invention described in the application relates to a panel of gene expression markers for patient with a tumor. The invention thus provides methods and compositions, e.g., kits, for evaluating gene expression levels of the markers and methods of using such gene expression levels to evaluate the likelihood of disease progression or response to chemotherapy or radiation therapy. Such information can be usd in determining prognosis and treatment options for cancer patients.

Abstract: A light sensing circuit for solving the problem of low reliability in illumination detection includes a photo transistor having a gate, a drain and a source; a first transistor electrically connecting between the gate and source of the photo transistor; a first capacitor electrically connecting between the gate and the drain of the photo transistor; a second transistor electrically connecting with the drain of the photo transistor, the first capacitor, and a data signal; a second capacitor electrically connecting between the source of the photo transistor and a ground contact; a third transistor electrically connecting with the photo transistor, the first transistor, and the second capacitor; and a switch adapted to alternatively connect the third transistor with a buffer or a zero signal. A control method of the above light sensing circuit is also disclosed. Therefore, the above identified problem can be surely solved.

Abstract: The present application provides compositions and methods useful for detecting and monitoring autoimmune diseases in a human subject. The methods comprise providing a moesin fragment for binding to an anti-moesin autoantibody and contacting the moesin fragment with a sample obtained from the human subject. The moesin fragment comprises the entire N-terminal FERM domain of a human moesin protein. The human subject has or is suspected of having an autoimmune disease such as connective tissue disease, systemic sclerosis, Sjogren's syndrome, or systemic lupus erythematosus.