Patents by Inventor Hua-Quan Miao

Hua-Quan Miao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTAGONISTS OF NEUROPILIN RECEPTOR FUNCTION AND USE THEREOF
    Publication number: 20150025224
    Abstract: The present invention relates to antagonists of neuropilin receptor function and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases.
    Type: Application
    Filed: October 1, 2014
    Publication date: January 22, 2015
    Inventors: Michael Klagsbrun, Shay Soker, Harry Hua-Quan Miao, Seiji Takashima
  • ANTAGONISTS OF NEUROPILIN RECEPTOR FUNCTION AND USE THEREOF
    Publication number: 20140056872
    Abstract: The present invention relates to antagonists of neuropilin receptor function and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases.
    Type: Application
    Filed: October 29, 2012
    Publication date: February 27, 2014
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Michael Klagsbrun, Shay Soker, Harry Hua-Quan Miao, Seiji Takashima
  • ANTAGONISTS OF NEUROPILIN RECEPTOR FUNCTION AND USE THEREOF
    Publication number: 20110002919
    Abstract: The present invention relates to antagonists of neuropilin receptor fuction and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases.
    Type: Application
    Filed: March 17, 2010
    Publication date: January 6, 2011
    Applicant: Children's Medical Center
    Inventors: Michael Klagsbrun, Shay Soker, Harry Hua-Quan Miao, Seiji Takashima
  • Antagonists of neuropilin receptor function and use thereof
    Patent number: 7731959
    Abstract: The present invention relates to antagonists of neuropilin receptor fuction and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: June 8, 2010
    Assignee: Children's Medical Center Corporation
    Inventors: Michael Klagsbrun, Shay Soker, Hua-Quan Miao, Seiji Takashima
  • Antagonists of neuropilin receptor function and use thereof
    Publication number: 20080076906
    Abstract: The present invention relates to antagonists of neuropilin receptor function and use thereof in the treatment of cancer particularly, metastatic cancer and angiogenic diseases.
    Type: Application
    Filed: August 16, 2007
    Publication date: March 27, 2008
    Applicant: Children's Medical Center Corporation
    Inventors: Michael Klagsbrun, Shay Soker, Hua-Quan Miao, Seiji Takashima
  • Antagonists of neuropilin receptor function and use thereof
    Patent number: 7335357
    Abstract: The present invention relates to antagonists of neuropilin receptor function and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: February 26, 2008
    Assignee: Children's Medical Center Corporation
    Inventors: Michael Klagsbrun, Shay Soker, Hua-Quan Miao, Seiji Takashima
  • Antagonists of neuroplin receptor function and use thereof
    Publication number: 20060251650
    Abstract: The present invention relates to antagonists of neuropilin receptor function and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases.
    Type: Application
    Filed: July 18, 2006
    Publication date: November 9, 2006
    Inventors: Michael Klagsbrun, Shay Soker, Hua-Quan Miao, Seiji Takashima
  • Neuropilins and use thereof in methods for diagnosis and prognosis of cancer
    Patent number: 6635421
    Abstract: The present invention relates to VEGF receptors (VEGFR) and neuropilins such as VEGF165R/NP-1 and NP-2 that are associated with metastatic potential of a malignant cell and their use in the diagnosis and prognosis of cancer. Preferred ones are VEGF165R/NP-1 and NP-2 but any neuropilin or VEGFR, where the constituents share at least about 85% homology with either of the above VEGF165R/NP-1 and NP-2 can be used. More preferably, such constituent shares at least 90% homology. Still more preferably, each constituent shares at least 95% homology.
    Type: Grant
    Filed: May 30, 2000
    Date of Patent: October 21, 2003
    Assignee: Children's Medical Center Corporation
    Inventors: Michael Klagsbrun, Shay Soker, Hua-Quan Miao, Seiji Takashima
  • Antagonists of neuropilin receptor function and use thereof
    Publication number: 20020132774
    Abstract: The present invention relates to antagonists of neuropilin receptor fuction and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases.
    Type: Application
    Filed: March 22, 2002
    Publication date: September 19, 2002
    Inventors: Michael Klagsbrun, Shay Soker, Hua-Quan Miao, Seiji Takashima
  • Quinazolinone containing pharmaceutical compositions for prevention of neovascularization and for treating malignancies
    Patent number: 6028075
    Abstract: The invention provides a composition for attenuating neovascularization and treating malignancies, including a pharmaceutically effective amount of a compound having a formula: ##STR1## wherein: R.sub.1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy;R.sub.2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy, andR.sub.3 is a member of the group consisting of hydrogen and lower alkenoxy carbonyl;as active ingredient therein, in combination with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: February 11, 1997
    Date of Patent: February 22, 2000
    Inventors: Mark Pines, Israel Vlodavsky, Arnon Nagler, Hua-Quan Miao