Abstract: The present invention provides for a method of using BOC/CDO hedgehog antagonists to inhibit hedgehog signaling, as well as treating and diagnosing disorders relating to hedgehog signaling or overexpression of hedgehog, including cancer, cell proliferative disorders, and angiogenesis, neurological disorders, as well as other conditions affected by hedgehog signaling such as hair growth, neural stem cell differentiation, chondrogenesis and osteogenesis, lung surfactant production, formation of lamellated bodies in lung cells.

Abstract: A rotary type hinge assembly for joining a body (310) and a cover (320) of a foldable electronic device has a first axis (A1) and a second axis (A2), and enables the cover open about the first axis and rotate about the second axis. The hinge assembly includes: a housing (210), rotatably attached to the body, and defining a container therein; a spring (220) received in the container; a driven element (230), wherein a first end thereof supports the spring, and a second end thereof has a cam surface (232); a cam (240), being coaxial with the driven element, a cam surface (243) defined on an end thereof including a mountain-shaped portion (244) having a flat surface engaging with the cam surface of the driven element; a rotary shaft (250); and a fixing means (260) for fixing the rotary shaft in the cover; wherein the rotary shaft extend through the cam, the driven element and the spring in that order, and is fixed in the housing.

Abstract: A hinge assembly includes a shaft (1), a prime mover spring (2) having two end portions (22, 23), a case drive member (3) having a cam face (311), a main body drive member (4) having a cam face (411) movably engaged with the cam face of the case drive member, a number of driving pins (5) each having one end abutting the case drive member, and a manual button (8) connected with an opposite end of each driving pin. The two end portions of the prime mover spring are respectively secured in a flange head (12) of the shaft and in the case drive member. The shaft extends through the prime mover spring, the case drive member and the main body drive member thereby integrating the hinge assembly into a complete unit.

Abstract: A rotary type hinge assembly for joining a body (310) and a cover (320) of a foldable electronic device has a first axis (A1) and a second axis (A2), and enables the cover open about the first axis and rotate about the second axis. The hinge assembly includes: a housing (210), rotatably attached to the body, and defining a container therein; a spring (220) received in the container; a driven element (230), wherein a first end thereof supports the spring, and a second end thereof has a cam surface (232); a cam (240), being coaxial with the driven element, a cam surface (243) defined on an end thereof including a mountain-shaped portion (244) having a flat surface engaging with the cam surface of the driven element; a rotary shaft (250); and a fixing means (260) for fixing the rotary shaft in the cover; wherein the rotary shaft extend through the cam, the driven element and the spring in that order, and is fixed in the housing.

Abstract: A hinge assembly includes a shaft (1), a prime mover spring (2) having two end portions (22, 23), a case drive member (3) having a cam face (311), a main body drive member (4) having a cam face (411) movably engaged with the cam face of the case drive member, a number of driving pins (5) each having one end abutting the case drive member, and a manual button (8) connected with an opposite end of each driving pin. The two end portions of the prime mover spring are respectively secured in a flange head (12) of the shaft and in the case drive member. The shaft extends through the prime mover spring, the case drive member and the main body drive member thereby integrating the hinge assembly into a complete unit.

Abstract: A hinge device includes a driven block (3), a cam (4), and a spring (7). The driven block includes two protrusions (31) projecting upwardly and downwardly respectively, the cam defines two opposite concave grooves (41) and two opposite arms (42), and the spring presses the driven block and the cam. Interfaces of the driven block (3) and the arms of the cam are plane surfaces, so that when the protrusions of the driven block are located on the plane surfaces, the hinge device is held in a steady state by the spring.

Abstract: An optical communication system (10), a method (100) for parallel modulation of an optical spectrum and a method (200) for parallel demodulation of the optical spectrum of modulated optical frequencies by the system (10) are described. The optical frequencies are provided in parallel to a modulation section (14) for modulating with data bits from a data signal source (16). The data bits are associated with an optical modulator (58) that controls passage of the optical spectrum at a plurality of predetermined optical frequencies based upon the data bits. The optical frequencies of the optical spectrum, modulated by the data bits, are then transmitted via a communication section (18) to an optical receiver (20) that is coupled to a demodulation section (22) of the system (10). Modulated optical frequencies are received as a modulated optical spectrum and demodulated in parallel by an optical demodulator (92) to derive the data bits.

Abstract: An optical communication system (10), a method (100) for parallel modulation of an optical spectrum and a method (200) for parallel demodulation of the optical spectrum of modulated optical frequencies by the system (10) are described. The optical frequencies are provided in parallel to a modulation section (14) for modulating with data bits from a data signal source (16). The data bits are associated with an optical modulator (58) that controls passage of the optical spectrum at a plurality of predetermined optical frequencies based upon the data bits. The optical frequencies of the optical spectrum, modulated by the data bits, are then transmitted via a communication section (18) to an optical receiver (20) that is coupled to a demodulation section (22) of the system (10). Modulated optical frequencies are received as a modulated optical spectrum and demodulated in parallel by an optical demodulator (92) to derive the data bits.