Abstract: A synthesis and an application of a phosphatase degrader are provided. The phosphatase degrader is a compound represented by formula I, or a salt thereof, or a deuterated compound thereof, or a stereoisomer thereof, or a solvate thereof, or a hydrate thereof, or a prodrug thereof. The compound can be used as a phosphatase degrader, especially as an SHP2 protein degrader, can treat malignant diseases such as tumors, and has good application prospects.

Abstract: Wireless communications between a base station and one or more wireless devices are described. Multiple downlink reference signals may correspond to multiple random access resources for a random access procedure. A base station may provide a set of downlink reference signals before a set of physical random access channels (PRACHs) are available for use. A wireless device performing a random access procedure may select two or more random access resources (e.g., PRACH occasions) based on the downlink reference signals. Using a listen before talk (LBT) procedure, the wireless device may select a first available random access resource from the two or more random access resources that are determined to be clear.

Abstract: According to one embodiment, a method, computer system, and computer program product for head-driven, self-captured photography is provided. The embodiment may include detecting a trigger event performed by a user while the user is interacting with a virtual environment. The embodiment may also include displaying a virtual camera within the virtual environment. The embodiment may further include modifying a location, a distance, and an orientation of the virtual camera in relation to the user based on a plurality of facial movement trigger events by the user. The embodiment may also include capturing one or more images using the virtual camera at the location, the distance, and the orientation based on a facial movement trigger event within the plurality of facial movement trigger events.

Abstract: A wireless device receives a first downlink control information (DCI) scheduling transport blocks (TBs) via physical downlink shared channels (PDSCHs) in slots, wherein the first DCI comprises a hybrid automatic repeat request (HARQ) feedback timing indicator indicating an inapplicable value and a first PDSCH group index for the PDSCHs. After receiving the TBs in the slots, the wireless device receives a second DCI indicating a second PDSCH group index; and transmits HARQ feedback information for the TBs in response to: the HARQ feedback timing indicator, of the first DCI, indicating the inapplicable value and the first PDSCH group index of the first DCI being equal to the second PDSCH group index of the second DCI.

Abstract: A first child access node receives, from a second access node, a first message comprising configuration parameters indicating radio resources for a cell served by the first child access node. The first child access node receives the first message from the second access node via a first parent access node of the first child access node. The first child access node receives, from the first parent access node, a downlink control information comprising an activation indication of the radio resources for the cell. The first child access node communicates, with a wireless device, transport blocks via the radio resources of the cell based on the activation indication and the first message.

Abstract: An electrode structure includes a substrate and a silver nanowire electrode disposed on the substrate. The electrode structure can be changed from an expanded state to a bent state with a bending radius of about 2-4 mm. The electrode structure includes a bending region and a first non-bending region and a second non-bending region respectively adjacent to the bending region in the bent state. The silver nanowire electrode has a change rate of a resistance value between the bent state and the expanded state of less than 10% in an electrode section of the bending region.

Abstract: The present disclosure provides a method and a device for evaluating a shipping risk caused by a sea ice disaster, and a computing device. The method includes: obtaining a historical daily-scale sea ice thickness data set of a monitored region; evaluating a risk level of sea ice disaster-inducing factors, vulnerability of a disaster-affected body and an exposure level in accordance with the historical daily-scale sea ice thickness data set; determining a disaster-bearing capability and a risk level of the disaster-affected body in the sea ice disaster in accordance with the risk level of the sea ice disaster-inducing factors, the vulnerability of the disaster-affected body and the exposure level; and evaluating shipping risks for different types of disaster-affected bodies within different return periods in accordance with the disaster-bearing capability and the risk level of the disaster-affected body in the sea ice disaster.

Abstract: Disclosed herein are muscle implants and methods of making muscle implants comprising one or more decellularized muscle matrices. The muscle matrices can, optionally, be joined to one or more decellularized dermal matrices. The muscle implants can be used to enhance muscle volume or to treat muscle damage, defects, and/or disorders. The decellularized muscle matrices in the implants retain at least some of the myofibers found in a muscle tissue prior to processing.

Abstract: A wireless device receives configuration parameters comprising pathloss reference linking indicators for SRS resource sets of a first cell associated with one or more TRPs, wherein each SRS resource set of the SRS resource sets comprises SRS resources, and each SRS resource set is associated with a respective pathloss reference linking indicator of the pathloss reference linking indicators, indicating a cell index identifying a pathloss reference cell. The wireless device transmits, via SRS resources of a first SRS resource set of the SRS resource sets in the first cell, SRSs with a transmission power determined based on a first pathloss RS of a first pathloss reference cell, wherein the first pathloss reference cell is indicated by a first pathloss reference linking indicator, of the pathloss reference linking indicators, associated with the first SRS resource set.

Abstract: A wireless device receives, from an integrated access backhaul (IAB) node, backhaul link failure information indicating a radio link failure between an IAB donor node and the IAB node. The wireless device transmits a radio link failure report indicating the backhaul link failure between the IAB donor node and the IAB node as causing a failure of a connection between the wireless device and the IAB donor node.

Abstract: Systems, apparatuses, and methods are described for wireless communications. A base station may transmit, to a wireless device, a DCI format comprising a downlink BWP indicator, an uplink BWP indicator, a PDSCH resource allocation, and a PUCCH resource allocation for HARQ ACK transmission. The wireless device may select, from a plurality of uplink active BWPs of the cell, an uplink active BWP based on the uplink BWP indicator. The wireless device may transmit the HARQ ACK via the selected uplink active BWP.

Abstract: A wireless device receives one or more radio resource control messages comprising configuration parameters of a configured uplink grant Type 1 associated with a cell. The wireless device transmits one or more transport blocks based on the configured uplink grant Type 1. The wireless device transitions the cell to a dormancy in response to receiving a downlink control information (DCI). The wireless device suspends the configured uplink grant Type 1 associated with the cell in response to the transitioning the cell to the dormancy.

Abstract: Wireless communications may use one or more devices for transmission and/or reception that may lead to potentially harmful exposure. One or more safety measures may be used for wireless communication devices, such as maximum power exposure (MPE) reporting and/or related operations. An MPE report may be sent based on MPE detection and one or more messages, such as for cell activation, bandwidth part (BWP) or other wireless resource activation and/or switching, and/or a discontinuous reception (DRX) or other state transition.

Abstract: Wireless communication techniques using a power saving mode are described. A wireless device may be configured with a plurality of power saving configurations. A base station may transmit an indication of a power saving configuration in the plurality of power saving configurations. The wireless device may monitor a power saving channel based on the indicated power saving configuration.

Abstract: Methods provide for creating compositions for masking non-animal derived protein off-notes. One embodiment of a method includes (a) selecting a non-animal protein for analysis; (b) identifying off-note compounds in the non-animal derived protein; (c) selecting possible antagonist molecules; (d) screening of the antagonist molecules for efficacy of masking the off-note compounds; and (e) combining the efficacious antagonist molecules to form a masking composition. The screening of the antagonist molecules is performed using an aroma blending device configured to deliver at least one aroma substance to the nasal cavities of a user.

Abstract: A wireless device receives a sidelink control information (SCI) that may schedule a transport block and may also indicate a first repetition value. The wireless device may also receive a transport block via a physical sidelink shared channel (PSSCH). Based on a comparison of the first repetition value received via the SCI and a repetition threshold, the wireless device may determine to transmit an acknowledgment for the received transport block. The wireless device may then transmit the acknowledgment for the received transport block.

Abstract: A wireless device receives RRC messages comprising configuration parameters of multicast transmissions, wherein the configuration parameters indicate CFRs comprising a number of resource blocks within a bandwidth part of a cell, a RNTI, and a value of a maximum MIMO layer indication for transmission via the CFRs. The wireless device receives, via the CFRs and based on the RNTI, a group common DCI indicating a multicast transmission of a TB, and the multicast transmission of the TB with a number of MIMO layers equal to or less than the value.

Abstract: The present disclosure provides a dialog method and system, an electronic device and a storage medium, and relates to the field of artificial intelligence (AI) technologies such as deep learning and natural language processing. A specific implementation scheme involves: rewriting a corresponding dialog state based on received dialog information of a user; determining to-be-used dialog action information based on the dialog information of the user and the dialog state; and generating a reply statement based on the dialog information of the user and the dialog action information. According to the present disclosure, the to-be-used dialog action information can be determined based on the dialog information of the user and the dialog state; and then the reply statement is generated based on the dialog action information, thereby providing an efficient dialog scheme.

Abstract: The present disclosure provides an ultra-high temperature resistant cement slurry system for cementing and the preparation method and use thereof. The cement slurry system comprises cement, an ultra-high temperature strength stabilizer, an ultra-high temperature reinforcing material, a density regulator, an ultra-high temperature suspension stabilizer, a dispersant, a fluid loss additive, a retarder, a defoaming agent and water, wherein the ultra-high temperature suspension stabilizer comprises an ether-based starch, an aluminosilicate and a polyalcohol polymer. The method for preparing the cement slurry system includes dry mixing and wet mixing raw materials homogeneously, respectively, and then homogeneously mixing the dry mix and wet mix to obtain the cement slurry system. The present disclosure further provides use of the cement slurry system for cementing in deep wells and ultra-deep wells at high and ultra-high temperatures.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive, from a base station, configuration information indicating a wake-up signal (WUS) configuration associated with a discontinuous reception (DRX) cycle, wherein the WU'S configuration indicates one or more WUS occasions. The UE may identify one or more conditions. The UE may refrain from monitoring at least one WUS occasion, from the one or more WUS occasions, based at least in part on the identification of the one or more conditions. The UE may monitor one or more resources during an on duration associated with the DRX cycle. Numerous other aspects are described.