Patents by Inventor Huai-Hsien Wang

Huai-Hsien Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glycopeptide-functionalized nanoparticles arrays for capturing and detecting biomolecules
    Patent number: 9329176
    Abstract: A surface-enhanced Raman spectroscopic (SERS) system for detecting a biomolecule. The system includes a substrate, an array of nanoparticles disposed on the substrate, each being partially embedded in the substrate and having a non-embedded surface, and a linking agent disposed on the non-embedded surface of each of the nanoparticles. The array of nanoparticles has a uniform interparticle gap of 1-50 nm and the linking agent is capable of binding to the biomolecule.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: May 3, 2016
    Assignee: Academia Sinica
    Inventors: Yuh-Lin Wang, Ting-Yu Liu, Huai-Hsien Wang
  • Glycopeptide-Functionalized Nanoparticles Arrays for Capturing and Detecting Biomolecules
    Publication number: 20120129707
    Abstract: A surface-enhanced Raman spectroscopic (SERS) system for detecting a biomolecule. The system includes a substrate, an array of nanoparticles disposed on the substrate, each being partially embedded in the substrate and having a non-embedded surface, and a linking agent disposed on the non-embedded surface of each of the nanoparticles. The array of nanoparticles has a uniform interparticle gap of 1-50 nm and the linking agent is capable of binding to the biomolecule.
    Type: Application
    Filed: November 18, 2010
    Publication date: May 24, 2012
    Applicant: Academia Sinica
    Inventors: Yuh-Lin Wang, Ting-Yu Liu, Huai-Hsien Wang
  • Substrate for surface-enhanced raman spectroscopy, sers sensors, and method for preparing same
    Patent number: 7453565
    Abstract: This invention relates to methods of preparing substrates that enhance the Raman signal of analytes in surface-enhanced Raman spectroscopy (SERS). The SERS-active substrate comprises an array of metal nanoparticles at least partially embedded in a template. The substrate's uniform and readily reproducible SERS-active properties with a wide range of analyte concentrations substantially enhance the power and utility of SERS. This invention also provides sensors, as well as Raman instruments, comprising the SERS-active substrates.
    Type: Grant
    Filed: June 13, 2006
    Date of Patent: November 18, 2008
    Assignee: Academia Sinica
    Inventors: Yuh-Lin Wang, Huai-Hsien Wang, Chih-Yi Liu, Juen-Kai Wang
  • SUBSTRATE FOR SURFACE-ENHANCED RAMAN SPECTROSCOPY, SERS SENSORS, AND METHOD FOR PREPARING SAME
    Publication number: 20070285657
    Abstract: This invention relates to methods of preparing substrates that enhance the Raman signal of analytes in surface-enhanced Raman spectroscopy (SERS). The SERS-active substrate comprises an array of metal nanoparticles at least partially embedded in a template. The substrate's uniform and readily reproducible SERS-active properties with a wide range of analyte concentrations substantially enhance the power and utility of SERS. This invention also provides sensors, as well as Raman instruments, comprising the SERS-active substrates.
    Type: Application
    Filed: June 13, 2006
    Publication date: December 13, 2007
    Applicant: ACADEMIA SINICA
    Inventors: Yuh-Lin WANG, Huai-Hsien WANG, Chih-Yi LIU, Juen-Kai WANG