Patents by Inventor Huai-Yao Chuang

Huai-Yao Chuang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered enzyme for enzyme replacement therapy
    Patent number: 10604747
    Abstract: An engineered enzyme, comprising an amino acid sequence that is at least 80% identical to the amino acid sequence of a human beta-glucuronidase, wherein the engineered enzyme exhibits a higher level of alpha-iduronidase enzymatic activity as compared to the human beta-glucuronidase.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: March 31, 2020
    Assignee: Academia Sinica
    Inventors: Steve Roffler, Huai-Yao Chuang
  • ENGINEERED ENZYME FOR ENZYME REPLACEMENT THERAPY
    Publication number: 20180346896
    Abstract: An engineered enzyme, comprising an amino acid sequence that is at least 80% identical to the amino acid sequence of a human beta-glucuronidase, wherein the engineered enzyme exhibits a higher level of alpha-iduronidase enzymatic activity as compared to the human beta-glucuronidase.
    Type: Application
    Filed: August 5, 2016
    Publication date: December 6, 2018
    Applicant: Academia Sinica
    Inventors: Steve Roffler, Huai-Yao Chuang