Abstract: The present invention relates to an S-configuration-containing amino benzamide pyridazinone compound, a preparation method therefor, and a pharmaceutical composition and application thereof. Specifically, the present invention relates to a compound represented by the following general formula I or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a pharmaceutical composition and application thereof. The S-configuration compound of the present application has very strong binding activity on class I histone deacetylase (HDAC1), and shows inhibitory activity on in-vitro proliferation of various tumor cells.

Abstract: A computing system based on Transparence Computing consists of clients and a server. There is no disk and no preinstalled OS on the client; a remote booting chip is set on the client's mainboard for downloading and loading the OS. Boot-supporting services, OS kernel mirrors, and applications are preset on the server; After being powered, the client broadcasts the boot request to the network and the server allocates network parameters for it. The client downloads an OS-selecting script from the server. After the user selects the needed OS, the client downloads and loads the selected OS from the server. Hence, the client fulfills the user's computing requirements just as a normal PC. The computing work is implemented on the client-side, during which the client can acquire corresponding resources such as applications, data, and documents from the server on demand.

Abstract: A computing system based on Transparence Computing consists of clients and a server. There is no disk and no preinstalled OS on the client; a remote booting chip is set on the client's mainboard for downloading and loading the OS. Boot-supporting services, OS kernel mirrors, and applications are preset on the server; After being powered, the client broadcasts the boot request to the network and the server allocates network parameters for it. The client downloads an OS-selecting script from the server. After the user selects the needed OS, the client downloads and loads the selected OS from the server. Hence, the client fulfills the user's computing requirements just as a normal PC. The computing work is implemented on the client-side, during which the client can acquire corresponding resources such as applications, data, and documents from the server on demand.