Abstract: A heat exchanger and an air conditioning system having the same. The heat exchanger includes at least one of a first heat exchanger unit and a second heat exchanger unit, and the heat exchanger has a V-shaped or inverted V-shaped shape. The first heat exchanger unit includes a first heat exchanger core segment and a second heat exchanger core segment, which are arranged side by side and each have heat exchange tube(s) and fin(s). A size of the first heat exchanger core segment of the first heat exchanger unit is larger than or equal to that of the second heat exchanger core segment of the first heat exchanger unit.

Abstract: Methods and systems for alignment for semiconductor applications are provided. One method includes determining different align-to-design offsets for multiple instances of an alignment target formed on a specimen by separately aligning images of the multiple instances of the alignment target generated by an imaging subsystem to a rendered image for the alignment target with different alignment methods, respectively. The method also includes identifying the multiple instances having a difference between the different align-to-design offsets below a predetermined threshold. In addition, the method includes determining a runtime align-to-design offset for the alignment target from the different align-to-design offsets determined for only the identified multiple instances. That runtime align-to-design offset can then be used in a process performed on the specimen with an imaging subsystem.

Abstract: A method for identifying a base in nucleic acid, a computer-readable storage medium, a computer program product, and a system. The method for identifying a base in nucleic acid comprises: mapping a coordinate of each bright spot in a bright spot set corresponding to a template onto an image to be inspected, and determining the position of a corresponding coordinate on said image (S11); determining the intensity of a signal at the position of the corresponding coordinate on said image, the intensity being a corrected intensity (S21); and comparing the intensity of the signal at the position of the corresponding coordinate on said image with the size of a first preset value, and determining a base type corresponding to the position on the basis of the comparison result, so as to achieve base calling (S31). The method may quickly and accurately identify a base, and achieve the determination of an order of nucleotides/bases of at least part of a sequence of a template.

Abstract: Disclosed in the present invention are a header assembly for a heat exchanger, and a heat exchanger. The header assembly includes: a header, having: a header wall, and a recess on the header wall or an opening penetrating the header wall at an end of the header wall; an end cap disposed at the end of the header wall to close the end of the header, the end cap having a hole, the opening or recess being at a side of the end cap that faces an end face of the end of the header wall; a distribution pipe, comprising a distribution part and a connection part, the connection part projecting from the end cap through the hole of the end cap from the distribution part; and a positioning member having a first end and a second end, the first end of the positioning member being connected to the connection part of the distribution pipe, and the second end of the positioning member being engaged in the opening or recess of the header wall of the header.

Abstract: Provided herein are methods of treating B-cell proliferative disorders (such as diffuse large B-cell lymphoma “DLBCL”) using immunoconjugates comprising anti-CD79b antibodies in combination with an anti-CD20 antibody, chemotherapy and a corticosteroid.

Abstract: A pathfinding method for a game object includes the following steps: the game object receives a movement request and sends a movement starting point and a movement ending point to a map server; the map server forms map information, and sends the map information to a pathfinding server, and the pathfinding server generates a movement path and sends the movement path to the map server; the map server determines whether there is an obstruction in the movement path; when there is no obstruction, the map server marks the movement path as valid and registers map units passed in the movement path; and when there is an obstruction, the map server sends a re-finding request to the pathfinding server, and the pathfinding server generates an updated path, until the map server determines that there is no obstruction in the updated path.

Abstract: A pipe clamp assembly and a heat exchanger having same with the pipe clamp assembly including a first pipe clamp member and a second pipe clamp member. The first pipe clamp member includes a first mounting surface located on a first side of the first pipe clamp member, and a second mounting surface located on a second side, opposite the first side, of the first pipe clamp member, and the second pipe clamp member includes a mounting surface facing the first pipe clamp member, and the mounting surface of the second pipe clamp member and the second mounting surface of the first pipe clamp member are used for clamping a pipe between the mounting surface of the second pipe clamp member and the second mounting surface of the first pipe clamp member.

Abstract: A heat exchanger and an air conditioning system having same, the heat exchanger including: a first manifold and a second manifold disposed at one and the same side of the heat exchanger; and multiple heat exchange tubes, each heat exchange tube including: two ends, the two ends respectively being a first end and a second end, the first end and second end being respectively connected to and in fluid communication with the first manifold and the second manifold; and multiple heat exchange parts, the multiple heat exchange parts including a first heat exchange part and a second heat exchange part, the first heat exchange part and second heat exchange part being respectively connected to and in fluid communication with the first end and the second end; in a lengthwise direction of the first manifold or second manifold, the ends of the multiple heat exchange tubes includes at least one pair of adjacently arranged first ends and/or at least one pair of adjacently arranged second ends.

Abstract: A manifold for a heat exchanger and a heat exchanger wherein the manifold includes: a pipe having an end portion; an end cover disposed at the end portion of the pipe and closing the end portion of the pipe to define an inner cavity in the pipe; and a discharge passage including: a first end opening into the inner cavity of the pipe, and a second end located at or adjacent to an end of the manifold and positioned at an outer peripheral surface of the manifold. The first end of the discharge passage is located on a side of the end cover facing the inner cavity of the pipe. According to embodiments of the disclosure, the stacking mounting of the heat exchangers in the axial direction of the manifold and the mounting of the heat exchanger with the end cover of the manifold contacting the ground can be achieved.

Abstract: Methods and systems for determining information for a specimen are provided. One system includes a model configured for generating a rendered image for an alignment target on a specimen from information for a design of the alignment target. The rendered image is a simulation of images of the alignment target on the specimen generated by an imaging subsystem. The system also includes a computer subsystem configured for modifying parameter(s) of the model based on variation in parameter(s) of the imaging subsystem and/or variation in process condition(s) used to fabricate the specimen. Subsequent to the modifying, the computer subsystem is configured for 10 generating an additional rendered image for the alignment target by inputting the information for the design of the alignment target into the model and aligning the additional rendered image to an image of the alignment target generated by the imaging subsystem.

Abstract: A method and device for image registration, and a computer program product. The method includes performing, based on a reference image, a first registration of an image to be registered, including determining a first offset between predetermined areas on the image and the reference image, and moving all bright spots on the image based on the first offset; performing, based on the reference image, a second registration with respect to the first registered image, including merging the first registered image and the reference image, calculating the offset of all overlapped bright spots in the predetermined area on the merged image to determine a second offset, two or more bright spots distanced by less than a predetermined number of pixels being one overlapped bright spot, and moving, on the basis of the second offset, all bright spots on the first registered image, thus implementing the registration of the image.

Abstract: The present invention provides a pathfinding method, and the method includes: determining a starting point and a target point of a target object; determining a distance range between the starting point and the target point on a grid map; selecting a pathfinding strategy corresponding to the distance range according to the distance range, wherein different pathfinding strategies are adopted for different distance ranges. The present invention further relates to a pathfinding apparatus and device, and a recording medium.

Abstract: A method and device for detecting bright spots on an image. The image is acquired from a field of view where a base extension reaction occurs, multiple nucleic acid molecules with optically detectable labels exist in the field of view where the base extension reaction occurs, and at least some of the nucleic acid molecules appear as bright spots on the image. The method includes preprocessing the image to obtain a preprocessed image; determining a critical value to simplify the preprocessed image to obtain a simplified image, determining a first bright spot detection threshold on the basis of the preprocessed image, and identifying candidate bright spots on the image on the basis of the preprocessed image and the simplified image, including determining a pixel matrix that satisfies at least two of conditions as a candidate bright spot.

Abstract: Global and local alignment energies are used in an image contrast metric. The image contrast metric can be used to find optical targets. Some pixels from a gradient magnitude image and a context range image from an optical image can be used to determine the image contrast metric. A heatmap from the image contrast metrics across part of a wafer can then be used to make a list of targets. Upper and lower confidence values can be applied to rank the available targets.

Abstract: Disclosed in the present invention are a header assembly for a heat exchanger, and a heat exchanger. The header assembly includes: a header, having: a header wall, and a recess on the header wall or an opening penetrating the header wall at an end of the header wall; an end cap disposed at the end of the header wall to close the end of the header, the end cap having a hole, the opening or recess being at a side of the end cap that faces an end face of the end of the header wall; a distribution pipe, comprising a distribution part and a connection part, the connection part projecting from the end cap through the hole of the end cap from the distribution part; and a positioning member having a first end and a second end, the first end of the positioning member being connected to the connection part of the distribution pipe, and the second end of the positioning member being engaged in the opening or recess of the header wall of the header.

Abstract: A method comprises: first, obtaining a to-be-recognized lane line image; then determining, based on the lane line image, a candidate pixel used to recognize a lane line region, to obtain a candidate point set, where the lane line region is a region of a location of a lane line in the lane line image and a surrounding region of the location of the lane line; then selecting a target pixel from the candidate point set, and obtaining at least three location points associated with the target pixel in a neighborhood, where the at least three location points are on one lane line; and finally, performing extension by using the target pixel as a start point and based on the at least three location points associated with the target pixel, to obtain a lane line point set corresponding to the target pixel.

Abstract: An effective sequencing method, the method comprising: (1) performing first sequencing on a sequencing template on a chip surface, so as to facilitate obtaining first sequencing data by means of first newly generated sequencing strands being formed, the sequencing template being connected onto the chip surface by means of a sequencing adapter; (2) performing first blocking treatment on 3? ends of at least a portion of the first newly generated sequencing strands; and (3) performing second sequencing on the sequencing template, so as to facilitate obtaining second sequencing data by means of second newly generated sequencing strands being formed.

Abstract: Provided herein are methods of treating B-cell proliferative disorders (such as diffuse large B-cell lymphoma “DLBCL”) using immunoconjugates comprising anti-CD79b antibodies in combination with an anti-CD20 antibody, chemotherapy and a corticosteroid.

Abstract: A method for identifying a base in nucleic acid, a computer-readable storage medium, a computer program product, and a system. The method for identifying a base in nucleic acid comprises: mapping a coordinate of each bright spot in a bright spot set corresponding to a template onto an image to be inspected, and determining the position of a corresponding coordinate on said image (S11); determining the intensity of a signal at the position of the corresponding coordinate on said image, the intensity being a corrected intensity (S21); and comparing the intensity of the signal at the position of the corresponding coordinate on said image with the size of a first preset value, and determining a base type corresponding to the position on the basis of the comparison result, so as to achieve base calling (S31). The method may quickly and accurately identify a base, and achieve the determination of an order of nucleotides/bases of at least part of a sequence of a template.

Abstract: An interactive control system for a game object including: a collision module, configured to assign a collision attribute to each game object; a moving module, configured to receive a moving instruction directed to a game group; an interaction module, configured to be coupled to the collision module, calculate a repulsive force of each game object, and represent an interaction form of the game object based on the repulsive force, wherein, when the game group is moved to the moving target, makes a group circle with a center of the game group as a center of the circle and a first length as a radius, when the game object is outside the group circle, it controls the collision module to impart a restoring force directing to the center of the circle to the game object, so as to control the game object to return to the game group.