Abstract: A computer-assisted system includes a manipulator arm coupled to an active imaging device and one or more processors configured to perform a process comprising: automatically directing a display device to display a shape overlay overlaid with an external view of a body, wherein the shape overlay is indicative of an extent of a field of view of the active imaging device relative to the body, and automatically directing the display device to display an auxiliary shape overlay overlaid with the external view of the body, wherein the auxiliary shape overlay is indicative of an extent of a potential field of view of the active imaging device relative to the body, the potential field of view distinct from the field of view.

Abstract: A mixed reality presentation system identifies an operating condition associated with an operation performed on a body while an active imaging device captures imagery of an internal view of the body. The mixed reality presentation system also determines, based on the identified operating condition, that a display device is to toggle a display of a shape overlay that is displayed together with an external view of the body and that is indicative of an extent of a field of view of the active imaging device relative to the body. Based on the determining that the display device is to toggle the display of the shape overlay, the mixed reality presentation system directs the display device to toggle the display of the shape overlay. Corresponding systems and methods are also disclosed.

Abstract: A mixed reality presentation system identifies an operating condition associated with an operation performed on a body while an active imaging device captures imagery of an internal view of the body. The mixed reality presentation system also determines, based on the identified operating condition, that a display device is to toggle a display of a shape overlay that is displayed together with an external view of the body and that is indicative of an extent of a field of view of the active imaging device relative to the body. Based on the determining that the display device is to toggle the display of the shape overlay, the mixed reality presentation system directs the display device to toggle the display of the shape overlay. Corresponding systems and methods are also disclosed.

Abstract: Fluid handling devices, systems, methods and kits are disclosed. Fluid handling devices according to the disclosure comprise: an inlet for receiving a sample; a reagent layer comprising, a substrate having a first surface and an opposing second surface, at least one reagent storage compartment configured to hold a reagent, and a seal in communication with the at least one reagent storage compartment; and a reaction layer having a first surface and an opposing second surface comprising, a reaction area, and an outlet in communication with the reaction area, wherein the reagent layer and reaction layer are adapted and configured to permit movement of at least one of the reagent layer and the reaction layer in a plane relative to the other layer.