Patents by Inventor Huan Lin

Huan Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200061119
    Abstract: The present disclosure provides an engineered stem cell, comprising a vector comprising a polynucleotide comprising a nucleic acid sequence of suicide gene, a nucleic acid sequence of immune checkpoint gene and a natural cytotoxicity triggering receptor or a TNF-related apoptosis-inducing ligand, wherein the stem cell is a tumor-targeting cell. The present disclosure also provides a method for treating a cancer or enhancing intratumor immunity or enhancing immunity in tumor microenvironment in a subject, comprising administering an effective amount of the engineered stem cell of the present disclosure to the subject.
    Type: Application
    Filed: March 18, 2019
    Publication date: February 27, 2020
    Inventors: Woei-Cherng SHYU, Chen-Huan LIN, Wei LEE, Chien-Lin CHEN, Long-Bin JENG, Chang-Hai TSAI
  • Publication number: 20190201450
    Abstract: A method for treating a multiple sclerosis is provided. The method includes administering a composition containing a plurality of mesenchymal stem cells to a subject in need for a treatment of the multiple sclerosis, in which each of the mesenchymal stem cells expresses insulin-like growth factor 1 receptors.
    Type: Application
    Filed: March 14, 2019
    Publication date: July 4, 2019
    Inventors: Woei-Cherng Shyu, Chen-Huan Lin, Wei Lee, Chia-Hung Hsieh, Chung-Y Hsu, Chang-Hai Tsai
  • Patent number: 10223991
    Abstract: A pixel includes a voltage dividing unit, a LC capacitor, a control unit, a first capacitor, a writing-in unit, and an adjusting unit. First terminal of the voltage dividing unit receives a first power voltage. The control terminal of the voltage dividing unit receives a first control signal. The LC capacitor is electrically coupled to the second terminal of voltage dividing unit. The control terminal of the control unit receives a second control signal. The writing-in unit provides a first pixel data signal to the first capacitor based on a third control signal. The adjusting unit receives a second power voltage. The adjusting unit divides voltage difference between the first and second power voltages based on the first pixel data signal stored in the first capacitor so as to control voltage stored in the LC capacitor, such that the LC corresponding to LC capacitor can be controlled.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: March 5, 2019
    Assignee: AU OPTRONICS CORPORATION
    Inventors: Ching-Huan Lin, Chia-Ting Hsieh, Norio Sugiura, Fang-Chen Luo
  • Patent number: 10069254
    Abstract: A retractable connecting device is adapted to connect a casing and a tray, wherein the tray is slidably disposed on the casing. The retractable connecting device includes a retractable guiding rod and an electrical connecting wire set. Two opposite ends of the retractable guiding rod are respectively fixed to the casing and the tray. The electrical connecting wire set includes a flexible wire and an adhesive structure. The two opposite ends of the flexible wire are respectively fixed to the casing and the tray. The adhesive structure is connected to the flexible wire. The adhesive structure has a through hole. The retractable guiding rod is disposed through the first through hole in order to guide the flexible wire to be folded or unfolded along the extending direction of the retractable guiding rod when the tray is moved with respect to the casing.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: September 4, 2018
    Assignees: INVENTEC (PUDONG) TECHNOLOGY CORPORATION, INVENTEC CORPORATION
    Inventor: Yu-Huan Lin
  • Patent number: 10050263
    Abstract: The present invention relates to a modified lithium ion battery anode material having high energy density, and a manufacturing process thereof, the anode material comprising, from inside to outside, a core, a transition layer and a shell layer. The anode material of the present invention has the advantages of high energy density, low surface activity, good storage performance, and a simple manufacturing process, and is suitable for large scale application.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: August 14, 2018
    Assignee: Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences
    Inventors: Yujing Bi, Chenyun Wang, Jingjing Zhou, Huan Lin, Deyu Wang
  • Patent number: 10035791
    Abstract: The present disclosure relates to a bicyclic compound, a pharmaceutical composition thereof, and its novel use. More particularly, the present disclosure relates to the bicyclic compound according to Formula I or Formula II, the pharmaceutical composition for treating a stroke, and the use of the bicyclic compound treating the stroke.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: July 31, 2018
    Assignee: China Medical University
    Inventors: Kuo-Hsiung Lee, Yu Zhao, Sheng-Chu Kuo, Chung-Y. Hsu, Woei-Cherng Shyu, Yu-Chian Chen, Chen-Huan Lin, Wei Lee, Chun-Wei Chiang, Chang-Hai Tsai
  • Publication number: 20180187146
    Abstract: A composition including adult pluripotent olfactory stem cells is provided. The adult pluripotent olfactory stem cells are obtained by culturing a cell mixture from an olfactory tissue of a mammal in media containing growth factors and then isolating cells which express B-lymphoma moloney murine leukemia virus insertion region-1 (Bmi-1).
    Type: Application
    Filed: June 6, 2017
    Publication date: July 5, 2018
    Inventors: Woei-Cherng SHYU, Chung-Y. HSU, Der-Yang CHO, Chen-Huan LIN, Wei LEE, San-Yuan CHEN, Long-Bin JENG, Chang-Hai TSAI
  • Publication number: 20180133259
    Abstract: A method for enhancing an insulin like growth factor 1 receptor expression of a mesenchymal stem cell is provided. The method includes culturing a plurality of mesenchymal stem cells expressing insulin-like growth factor 1 receptors in media containing human cord blood serum to enhance the insulin like growth factor 1 receptor expression of the mesenchymal stem cells.
    Type: Application
    Filed: December 26, 2017
    Publication date: May 17, 2018
    Inventors: Woei-Cherng SHYU, Chen-Huan LIN, Wei LEE, Chia-Hung HSIEH, Chung-Y. HSU, Chang-Hai TSAI
  • Publication number: 20180122319
    Abstract: A pixel includes a voltage dividing unit, a LC capacitor, a control unit, a first capacitor, a writing-in unit, and an adjusting unit. First terminal of the voltage dividing unit receives a first power voltage. The control terminal of the voltage dividing unit receives a first control signal. The LC capacitor is electrically coupled to the second terminal of voltage dividing unit. The control terminal of the control unit receives a second control signal. The writing-in unit provides a first pixel data signal to the first capacitor based on a third control signal. The adjusting unit receives a second power voltage. The adjusting unit divides voltage difference between the first and second power voltages based on the first pixel data signal stored in the first capacitor so as to control voltage stored in the LC capacitor, such that the LC corresponding to LC capacitor can be controlled.
    Type: Application
    Filed: December 26, 2017
    Publication date: May 3, 2018
    Inventors: Ching-Huan LIN, Chia-Ting HSIEH, Norio SUGIURA, Fang-Chen LUO
  • Patent number: 9892702
    Abstract: A pixel includes a voltage dividing unit, a LC capacitor, a control unit, a first capacitor, a writing-in unit, and an adjusting unit. First terminal of the voltage dividing unit receives a first power voltage. The control terminal of the voltage dividing unit receives a first control signal. The LC capacitor is electrically coupled to the second terminal of voltage dividing unit. The control terminal of the control unit receives a second control signal. The writing-in unit provides a first pixel data signal to the first capacitor based on a third control signal. The adjusting unit receives a second power voltage. The adjusting unit divides voltage difference between the first and second power voltages based on the first pixel data signal stored in the first capacitor so as to control voltage stored in the LC capacitor, such that the LC corresponding to LC capacitor can be controlled.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: February 13, 2018
    Assignee: AU OPTRONICS CORPORATION
    Inventors: Ching-Huan Lin, Chia-Ting Hsieh, Norio Sugiura, Fang-Chen Luo
  • Patent number: 9829757
    Abstract: A display device includes a light source module, a first light modulation module, a first polarizer layer, and a first color modulation layer. The light source module generates a first color light that is polarized to the first light modulation module, wherein the first light modulation module selectively modulates the polarization direction of the first color light. The first polarizer layer then receives the first color light and selectively blocks, partially blocks, or does not block the first color light from passing through. The first color modulation layer receives the first color light and generates a second color light.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: November 28, 2017
    Assignee: AU OPTRONICS CORPORATION
    Inventors: Kuo-Tsung Chen, Cho-Yan Chen, Ching-Huan Lin, Chu-Yu Liu
  • Patent number: 9819152
    Abstract: This invention discloses a method for the fabrication of GaN-based vertical cavity surface-emitting devices featuring a silicon-diffusion defined current blocking layer (CBL). Such devices include vertical-cavity surface-emitting laser (VCSEL) and resonant-cavity light-emitting diode (RCLED). The silicon-diffused P-type GaN region can be converted into N-type GaN and thereby attaining a current blocking effect under reverse bias. And the surface of the silicon-diffused area is flat so the thickness of subsequent optical coating is uniform across the emitting aperture. Thus, this method effectively reduces the optical-mode field diameter of the device, significantly decreases the spectral width of LED, and produces single-mode emission of VCSEL.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: November 14, 2017
    Assignee: NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Ping-Hui Yeh, Meng-Chun Yu, Jia-Huan LIn, Ching-Chin Huang
  • Publication number: 20170298049
    Abstract: The present disclosure relates to a bicyclic compound, a pharmaceutical composition thereof, and its novel use. More particularly, the present disclosure relates to the bicyclic compound according to Formula I or Formula II, the pharmaceutical composition for treating a stroke, and the use of the bicyclic compound treating the stroke.
    Type: Application
    Filed: October 6, 2016
    Publication date: October 19, 2017
    Inventors: Kuo-Hsiung LEE, Yu ZHAO, Sheng-Chu KUO, Chung-Y. HSU, Woei-Cherng SHYU, Yu-Chian CHEN, Chen-Huan LIN, Wei LEE, Chun-Wei CHIANG, Chang-Hai TSAI
  • Patent number: 9761996
    Abstract: The invention provides a M.2 interface memory device and a M.2 interface connection seat insertedly provided thereof. The M.2 interface memory device comprises a M.2 interface card and a housing provided with at least one guide groove. The M.2 interface connection seat is disposed on a circuit board, and comprises two arms and a base comprising a M.2 interface slot. At least one arm is provided with a guide rail. An opening direction of the M.2 interface slot is horizontal to a surface of the circuit board. When the M.2 interface card is inserted into the M.2 interface slot in a horizontal direction, the M.2 interface memory device will be fixed within the M.2 interface connection seat by embedding between the guide groove and the guide rail. Thus, M.2 interface memory devices of a variety of specification lengths are able to be inserted into the M.2 interface connection seat.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: September 12, 2017
    Assignee: INNODISK CORPORATION
    Inventors: Chen-Huan Lin, Hsiao-Yu Wang
  • Patent number: 9718835
    Abstract: The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: August 1, 2017
    Assignees: CHINA MEDICAL UNIVERSITY HOSPITAL, THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Kuo-Hsiung Lee, Keduo Qian, Xiaoming Yang, Masuo Goto, Ying-Qian Liu, Yong-Long Zhao, Liu Yang, Mei-Juan Wang, Zhi-Jun Zhang, Tian-Shung Wu, Che-Ming Teng, Chih-Ya Wang, Shiow-Lin Pan, Sheng-Chu Kuo, Hsin-Yi Hung, Ling-Chu Chang, Yang-Chang Wu, Min-Tsang Hsieh, Chung Y. Hsu, Woei-Cherng Shyu, Chen-Huan Lin
  • Publication number: 20170179642
    Abstract: The invention provides a M.2 interface memory device and a M.2 interface connection seat insertedly provided thereof. The M.2 interface memory device comprises a M.2 interface card and a housing provided with at least one guide groove. The M.2 interface connection seat is disposed on a circuit board, and comprises two arms and a base comprising a M.2 interface slot. At least one arm is provided with a guide rail. An opening direction of the M.2 interface slot is horizontal to a surface of the circuit board. When the M.2 interface card is inserted into the M.2 interface slot in a horizontal direction, the M.2 interface memory device will be fixed within the M.2 interface connection seat by embedding between the guide groove and the guide rail. Thus, M.2 interface memory devices of a variety of specification lengths are able to be inserted into the M.2 interface connection seat.
    Type: Application
    Filed: July 28, 2016
    Publication date: June 22, 2017
    Inventors: Chen-Huan LIN, Hsiao-Yu WANG
  • Patent number: 9653032
    Abstract: A liquid crystal (LC) pixel circuit of a LC display panel includes a first, a second, a third and a fourth switches, a LC capacitor and a storage capacitor. A first and a control terminals of the first switch respectively receive a common voltage and a first gate signal. A first and a control terminals of the second switch respectively receive a data voltage and a second gate signal. The storage capacitor and the LC capacitor electrically connect between second terminals of the first and second switches. A first and a control terminals of the third switch respectively receive the common voltage and a third gate signal. A first and a control terminals of the fourth switch respectively receive a set voltage and a fourth gate signal. Second terminals of the third and the fourth switches respectively connect to the second terminals of the second and the first switches.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: May 16, 2017
    Assignee: Au Optronics Corporation
    Inventors: Chih-Lung Lin, Chia-En Wu, Mao-Hsun Cheng, Bo-Shiang Tzeng, Ching-Huan Lin
  • Publication number: 20170104315
    Abstract: This invention discloses a method for the fabrication of GaN-based vertical cavity surface-emitting devices featuring a silicon-diffusion defined current blocking layer (CBL). Such devices include vertical-cavity surface-emitting laser (VCSEL) and resonant-cavity light-emitting diode (RCLED). The silicon-diffused P-type GaN region can be converted into N-type GaN and thereby attaining a current blocking effect under reverse bias. And the surface of the silicon-diffused area is flat so the thickness of subsequent optical coating is uniform across the emitting aperture.
    Type: Application
    Filed: October 7, 2015
    Publication date: April 13, 2017
    Inventors: PING-HUI YEH, Meng-Chun Yu, Jia-Huan Lin, Ching-Chin Huang
  • Publication number: 20170077630
    Abstract: The invention provides a connector and a connection seat insertedly provided thereof, particularly to a connector and a connection seat conforming to M.2 interface standard specification. The M.2 interface connector comprises a M.2 interface card and a housing. The housing is used for cladding the body of the M.2 interface card. The housing is provided on at least one side surface thereof with at least one fixed member. The M.2 interface card is having a connection interface protruding from the bottom end of the housing. The M.2 interface connection seat is disposed on a circuit board, and it's top end is provided with a slot. The opening direction of the slot will be perpendicular to the surface of the circuit board. When the connection interface of the M.2 interface connector is inserting into the slot of the M.2 interface connection seat based on a vertical direction, the fixed member of the housing will be fixed on the body of the M.2 interface connection seat. Therefore, the M.
    Type: Application
    Filed: December 8, 2015
    Publication date: March 16, 2017
    Inventors: CHEN-HUAN LIN, HSIAO-YU WANG
  • Publication number: 20170020924
    Abstract: A mesenchymal stem cell is provided. The mesenchymal stem cell that expresses an insulin-like growth factor 1 receptor have been cultured in media containing human cord blood serum and isolated, such that an insulin-like growth factor 1 receptor expression is enhanced in the isolated mesenchymal stem cells.
    Type: Application
    Filed: November 6, 2015
    Publication date: January 26, 2017
    Inventors: Woei-Cherng SHYU, Chen-Huan LIN, Wei LEE, Chia-Hung HSIEH, Chung-Y. HSU, Chang-Hai TSAI