Abstract: A mobile HEB and TEP mitigation device includes a mobile body capable of movement within or upon a body of water. Located within the mobile body is a hydrodynamic separation system which includes a water inlet, a hydrodynamic separation unit and a collection tank. The hydrodynamic separation unit includes two outputs, one for a clean stream output line containing clean water and arranged to re-circulate the clean water, and another for a concentrate stream output line, the concentrate stream output line configured to place concentrated water containing potentially harmful bio-organic materials into the collection tank. Also included on the mobile body is a power source and an engine/steering unit, wherein the steering portion of the engine/steering unit provides a capacity to move the mobile body in an intended direction. The mitigation device may also be used as an embedded part of an on-shore arrangement.

Abstract: Systems and methods are used to concentrate and extract platelets from blood, where an aggregation arrangement is configured to aggregate red blood cells in the blood. The aggregated red blood cells are provided to a separation arrangement which is configured to separate the aggregated red blood cells from platelets in the blood plasma. Finally a concentration arrangement is configured to concentrate the platelets for extraction and further use.

Abstract: Method and Systems for extracting a concentrated sample of particles include priming a concentrate reservoir by passing a fluid through the concentrate reservoir to remove air. The concentrate reservoir has a first end with an opening and second end with an opening. The second end of the concentrate reservoir is closed off, and particles are accumulated within the concentrate reservoir by use of a particle concentrator. Thereafter, the first end of the concentrate reservoir is closed off, isolating the concentrate reservoir from particle concentrator, from which the particles were obtained. The second end of the concentrate reservoir is thereafter opened, and the particles of the concentrated sample in the concentrate reservoir are extracted to a sample capture reservoir through the second end opening of the concentrate reservoir.

Abstract: A method and system for splitting fluid flow in an outlet of a particle separation device is provided. The system may include static or passive mechanisms or subsystems. These mechanisms could also be modular and interchangeable to provide for preset fluid split divisions of 20:80, 30:70, 40:60, 50:50, . . . etc. In other forms of the presently described embodiments, the system is adjustable and variable. In still another form of the presently described embodiments, the system allows for differential pressure control at the outlets to facilitate the flow of varying size particles or particle bands in the respective channels or paths.

Abstract: A system and method permits for the separation of auto-fluorescence from a signal by applying a single probe to a sample, exciting the sample with a single wavelength light source, thereby emitting a light a distance from the light source. The emitted light is split, and the split light is collected into two or more distinct channels. A first channel of the distinct channels is positioned closer to the light source than a second distinct channel of the distinct channels, and the second channel is closer to the emission frequency of the single probe than is the first channel. The light collected in the first channel and the light collected in the second channel are investigated, and an output signal is generated based upon the investigation.

Abstract: A transformational approach to water treatment is provided that incorporates membrane-free filtration with dynamic processing of the fluid to significantly reduce treatment times, chemical cost, land use, and operational overhead. This approach provides hybrid capabilities of filtration, together with chemical treatment, as the water is transported through various spiral stages.

Abstract: A system and method permits for the separation of auto-fluorescence from a signal by applying a single probe to a sample, exciting the sample with a single wavelength light source, thereby emitting a light a distance from the light source. The emitted light is split, and the split light is collected into two or more distinct channels. A first channel of the distinct channels is positioned closer to the light source than a second distinct channel of the distinct channels, and the second channel is closer to the emission frequency of the single probe than is the first channel. The light collected in the first channel and the light collected in the second channel are investigated, and an output signal is generated based upon the investigation.

Abstract: Method and Systems for extracting a concentrated sample of particles include priming a concentrate reservoir by passing a fluid through the concentrate reservoir to remove air. The concentrate reservoir has a first end with an opening and second end with an opening. The second end of the concentrate reservoir is closed off, and particles are accumulated within the concentrate reservoir by use of a particle concentrator. Thereafter, the first end of the concentrate reservoir is closed off, isolating the concentrate reservoir from particle concentrator, from which the particles were obtained. The second end of the concentrate reservoir is thereafter opened, and the particles of the concentrated sample in the concentrate reservoir are extracted to a sample capture reservoir through the second end opening of the concentrate reservoir.

Abstract: Provided is a method for obtaining a position of an object. A slide which carries at least one object and has reticle marks arranged at positions which form substantially a right angle, is positioned in a slide holder of a first imaging system. A first coordinate space of the imaging system is defined, and coordinates of the reticle marks in the first coordinate space are designated. A second coordinate space of a second imaging system is defined, and the coordinates of the reticle marks in the second coordinate space is designated. Using the designated coordinates of the reticle marks of the first coordinate space, the coordinate conversion parameters are computed. Thereafter, coordinates of at least one object in the first coordinate space are designated, and the first coordinate space coordinates of the object are converted into unique coordinates in a second coordinate space, using the coordinate conversion parameters.

Abstract: In accordance with one aspect of the present application, an imager and method for detecting and locating rare cells in a sample is disclosed. An imager stage supports the sample. A fiber optic bundle has a proximate bundle end of first fiber ends arranged to define an input aperture viewing the sample on the translation stage. The fiber optic bundle further has a distal bundle end of second fiber ends arranged to define an output aperture shaped differently from the input aperture and disposed away from the imager stage. A scanning radiation source is arranged in fixed relative position to the input aperture. The scanning radiation source scans a radiation beam on the sample within a viewing area of the input aperture. The radiation beam interacts with the sample to produce a light signal that is reflected, scattered, transmitted, re-emitted, or otherwise collected and received by the input aperture and transmitted via the fiber optic bundle to the output aperture.

Abstract: Provided is a method for obtaining a position of an object. A slide which carries at least one object and has reticle marks arranged at positions which form substantially a right angle, is positioned in a slide holder of a first imaging system. A first coordinate space of the imaging system is defined, and coordinates of the reticle marks in the first coordinate space are designated. A second coordinate space of a second imaging system is defined, and the coordinates of the reticle marks in the second coordinate space is designated. Using the designated coordinates of the reticle marks of the first coordinate space, the coordinate conversion parameters are computed. Thereafter, coordinates of at least one object in the first coordinate space are designated, and the first coordinate space coordinates of the object are converted into unique coordinates in a second coordinate space, using the coordinate conversion parameters.

Abstract: In accordance with one aspect of the present application, an imager and method for detecting and locating rare cells in a sample is disclosed. An imager stage supports the sample. A fiber optic bundle has a proximate bundle end of first fiber ends arranged to define an input aperture viewing the sample on the translation stage. The fiber optic bundle further has a distal bundle end of second fiber ends arranged to define an output aperture shaped differently from the input aperture and disposed away from the imager stage. A scanning radiation source is arranged in fixed relative position to the input aperture. The scanning radiation source scans a radiation beam on the sample within a viewing area of the input aperture. The radiation beam interacts with the sample to produce a light signal that is reflected, scattered, transmitted, re-emitted, or otherwise collected and received by the input aperture and transmitted via the fiber optic bundle to the output aperture.