Abstract: A device comprises a first comparator to generate a first clock signal based on a reference voltage and a first voltage at an output of a switched-capacitor power converter (SCPC), and a second comparator to generate a first control signal based on the first voltage and a threshold voltage. A sensor is to generate a second control signal based on one of a level of a current of the first clock signal, or a duty cycle of the first clock signal. A frequency divider circuit is to generate a second clock signal based on the first control signal and the second control signal, and in some embodiments, further based on one of the first clock signal or a third clock signal. Controller circuitry is to operate switch circuitry of the SCPC based on the first clock signal.

Abstract: A high-speed connector includes an insulating body and a terminal module. The terminal module includes a number of terminal groups. Each terminal group includes a number of ground terminals, a number of signal terminals and two shielding pieces. The ground terminal includes a ground pin. The signal terminal includes a signal pin. Each shielding piece includes a number of convex portions and a number of surrounding portions. The ground pins and the signal pins are distributed in a staggered manner. At least one ground pin is in contact with the convex portions of the two shielding pieces. The surrounding portion surrounds the signal pins. When the ground pins and the signal pins are no longer in the same plane or the same row, the shielding piece can prevent cross-talk among signals, thereby improving the transmission quality.

Abstract: A biosensing platform for in-situ sampling and target detection based on upconversion luminescence, including: an upconversion luminescent paper-based microfluidic device, an upconversion luminescent biosensor, and a portable detection device based on smartphone imaging. The upconversion luminescent paper-based microfluidic device is configured to sample a to-be-detected substance in situ. The upconversion luminescent biosensor is configured to allow a target to specifically recognize the to-be-detected substance. The portable detection device is configured to detect a content of the to-be-detected substance. The upconversion luminescent biosensor is prepared as follows. (S1) An upconversion nanoparticle seed is prepared. (S2) Core-shell upconversion nanoparticles are prepared. (S3) Core-shell-shell upconversion nanoparticles (UCNPs) are prepared. (S4) The UCNPs is subjected to hydrophilic modification. (S5) The hydrophilically-modified UCNPs are modified with DNA.

Abstract: A microfluidic chip device based on a magnetic field-controlled fluorescently labeled cell sorting method and a use method are disclosed. The microfluidic chip comprises a sample channel, two sheath fluid channels, a first fluorescence detection area, a second fluorescence detection area, a magnetic field control system, a magnetic field-controlled cell sorting area, a target cell channel, and a waste fluid channel. Based on fluorescence signals labeled on the cells, the FACS system is combined with a magnetic field-controlled sorting system to achieve automated cell sorting, which not only miniaturizes and automates the sorting detection integration, but also has the advantages of easy and economical operation. The device sorts both a large number of cell samples and a small number of cell samples, thus overcoming the defects of a flow cytometer.

Abstract: The wearing article has front and rear waist regions and a crotch region wherein a first waist region as one of the front and rear waist regions includes an outer layer sheet located on non-skin-facing surface, an inner layer sheet located on the inner side compared to the outer layer sheet and an interlayer sheet interlaid between the inner and outer layer sheets and having a decorative element being visually recognizable from the non-skin-facing surface side of the outer layer sheet and the outer layer sheet is nonwoven fabrics formed from crimped conjugated fibers and a brightness value of the inner layer sheet is higher than a brightness value of the outer layer sheet.

Abstract: A shaped non-woven fabric for an absorbent has a first surface and a second surface and is usable with the second surface facing a constituent member of an absorbent article. The shaped non-woven fabric is includes a thermoplastic resin fiber. The non-woven fabric includes a plurality of first recesses which have openings in the first surface and are recessed toward the second surface, and a plurality of through-holes which penetrate from the first surface to the second surface. Each of the plurality of first recesses has a peripheral wall section which extends in the thickness direction from the end edges of the openings toward the second surface, and a bottom section connected to the end edge of the peripheral wall section. At least a portion of the plurality of first recesses includes a hole section which penetrates from the first surface to the second surface.

Abstract: A shaped non-woven fabric for an absorbent has a first surface and a second surface and is usable with the second surface facing a constituent member of an absorbent article. The shaped non-woven fabric is includes a thermoplastic resin fiber. The non-woven fabric includes a plurality of first recesses which have openings in the first surface and are recessed toward the second surface, and a plurality of through-holes which penetrate from the first surface to the second surface. Each of the plurality of first recesses has a peripheral wall section which extends in the thickness direction from the end edges of the openings toward the second surface, and a bottom section connected to the end edge of the peripheral wall section. At least a portion of the plurality of first recesses includes a hole section which penetrates from the first surface to the second surface.

Abstract: Provided are compositions and methods that involve cancer cells which are modified so that they can form orthotopic tumors in a non-human mammal, and wherein metastasis of the tumor can be controlled. The cancer cells, which may be human cancer cells, are modified so that expression of a human chemokine receptor can be modulated. Modulating expression of the human chemokine receptor allows selective initiation of metastasis. Kits which contain the modified cancer cells are provided. A method for identifying agents which can inhibit metastasis using non-human mammals having orthotopic tumors formed using the modified cancer cells is also included.

Abstract: The wearing article has front and rear waist regions and a crotch region wherein a first waist region as one of the front and rear waist regions includes an outer layer sheet located on non-skin-facing surface, an inner layer sheet located on the inner side compared to the outer layer sheet and an interlayer sheet interlaid between the inner and outer layer sheets and having a decorative element being visually recognizable from the non-skin-facing surface side of the outer layer sheet and the outer layer sheet is nonwoven fabrics formed from crimped conjugated fibers and a brightness value of the inner layer sheet is higher than a brightness value of the outer layer sheet.

Abstract: Provided are compositions and methods that involve cancer cells which are modified so that they can form orthotopic tumors in a non-human mammal, and wherein metastasis of the tumor can be controlled. The cancer cells, which may be human cancer cells, are modified so that expression of a human chemokine receptor can be modulated. Modulating expression of the human chemokine receptor allows selective initiation of metastasis. Kits which contain the modified cancer cells are provided. A method for identifying agents which can inhibit metastasis using non-human mammals having orthotopic tumors formed using the modified cancer cells is also included.