Patents by Inventor Huanhuan LI

Huanhuan LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240118255
    Abstract: A buffer assembly for a noble gas isotope analysis device, including an air inlet pipe and an air-pressure buffer member. The air inlet pipe is connected to the noble gas isotope analysis device, and is provided with a valve. The air-pressure buffer member is provided in the air inlet pipe, and includes a connecting pipe arranged inside the air inlet pipe. Multiple pneumatic components are sleeved outside the connecting pipe, and are configured to be deformed under the action of a gas flow to decelerate the gas flow. A noble gas isotope analysis device including the buffer assembly and an isotope analysis method using the noble gas isotope analysis device are also provided.
    Type: Application
    Filed: December 19, 2023
    Publication date: April 11, 2024
    Inventors: Chunhui CAO, Liwu LI, Huanhuan ZHAO
  • Patent number: 11951575
    Abstract: Disclosed are an automatic welding system and method for large structural parts based on hybrid robots and 3D vision. The system comprises a hybrid robot system composed of a mobile robot and an MDOF robot, a 3D vision system, and a welding system used for welding. The rough positioning technique based on a mobile platform and the accurate recognition and positioning technique based on high-accuracy 3D vision are combined, so the working range of the MDOF robot in the XYZ directions is expanded, and flexible welding of large structural parts is realized. The invention adopts 3D vision, thus having better error tolerance and lower requirements for the machining accuracy of workpieces, positioning accuracy of mobile robots and placement accuracy of the workpieces; and the cost is reduced, the flexibility is improved, the working range is expanded, labor is saved, production efficiency is improved, and welding quality is improved.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: April 9, 2024
    Inventors: Tao Yang, HuanHuan Li, Lei Peng, JunWei Jiang, Li Ma, QingFeng Liu, NiNi Zhang, Fang Wang
  • Publication number: 20240092910
    Abstract: The present invention provides a B7-H3 nanobody, the preparation method and use thereof. The B7-H3 nanobody comprises framework regions 1-4 (FR 1-4) and complementarity determining regions 1-3 (CDR 1-3), can specifically bind to B7-H3, and can be used for detecting B7-H3 molecules, and be used for the treatment of various malignant tumors with abnormal expression of B7-H3 molecule.
    Type: Application
    Filed: October 9, 2020
    Publication date: March 21, 2024
    Applicants: Dartsbio Pharmaceuticals Ltd., Shanghai Mabstone Biotechnology Ltd., Shenzhen Innovastone Biopharma Ltd.
    Inventors: Chunhe WANG, Yi-li CHEN, Xinyuan LIU, Weidong LUO, Guojian LIU, Huanhuan LI, Yijun LIN
  • Publication number: 20240075474
    Abstract: A biosensing platform for in-situ sampling and target detection based on upconversion luminescence, including: an upconversion luminescent paper-based microfluidic device, an upconversion luminescent biosensor, and a portable detection device based on smartphone imaging. The upconversion luminescent paper-based microfluidic device is configured to sample a to-be-detected substance in situ. The upconversion luminescent biosensor is configured to allow a target to specifically recognize the to-be-detected substance. The portable detection device is configured to detect a content of the to-be-detected substance. The upconversion luminescent biosensor is prepared as follows. (S1) An upconversion nanoparticle seed is prepared. (S2) Core-shell upconversion nanoparticles are prepared. (S3) Core-shell-shell upconversion nanoparticles (UCNPs) are prepared. (S4) The UCNPs is subjected to hydrophilic modification. (S5) The hydrophilically-modified UCNPs are modified with DNA.
    Type: Application
    Filed: October 31, 2023
    Publication date: March 7, 2024
    Inventors: Quansheng CHEN, Jizhong WU, Qin OUYANG, Wenya WEI, Huanhuan LI, Jingui ZHANG, Jinghao YU
  • Publication number: 20240009304
    Abstract: Provided is use of an NGF antibody in CIPN pain. In particular, the NGF antibody blocks the interaction of nerve growth factors (NGF) with receptors thereof, and thus can treat and/or prevent chemotherapy-induced peripheral neuropathy (CIPN) pain.
    Type: Application
    Filed: November 10, 2021
    Publication date: January 11, 2024
    Applicants: Dartsbio Pharmaceuticals Ltd., Shanghai Mabstone Biotechnology Co., Ltd.
    Inventors: Chunhe WANG, Zuobin XIE, Huaping DING, Yili CHEN, Huanhuan LI, Lei TANG
  • Publication number: 20230390853
    Abstract: Disclosed are an automatic welding system and method for large structural parts based on hybrid robots and 3D vision. The system comprises a hybrid robot system composed of a mobile robot and an MDOF robot, a 3D vision system, and a welding system used for welding. The rough positioning technique based on a mobile platform and the accurate recognition and positioning technique based on high-accuracy 3D vision are combined, so the working range of the MDOF robot in the XYZ directions is expanded, and flexible welding of large structural parts is realized. The invention adopts 3D vision, thus having better error tolerance and lower requirements for the machining accuracy of workpieces, positioning accuracy of mobile robots and placement accuracy of the workpieces; and the cost is reduced, the flexibility is improved, the working range is expanded, labor is saved, production efficiency is improved, and welding quality is improved.
    Type: Application
    Filed: July 15, 2022
    Publication date: December 7, 2023
    Inventors: Tao YANG, HuanHuan LI, Lei PENG, JunWei JIANG, Li MA, QingFeng LIU, NiNi ZHANG, Fang WANG
  • Patent number: 11773322
    Abstract: A method of preparing a dye-functionalized flexible upconversion-luminescence solid-phase sensor, including: preparation of upconversion-luminescence nanoparticles, preparation of an upconversion nanoparticle-doped solid-phase sensor, and preparation of a dye-functionalized flexible upconversion-luminescence solid-phase sensor. A method for detecting a gaseous pollutant is also provided, including: preparing a dye-functionalized flexible upconversion-luminescence solid-phase sensor through the above method; establishing a prediction model; and substituting a fluorescence intensity of a sample into the prediction model to calculate the gaseous pollutant concentration in the sample.
    Type: Grant
    Filed: April 28, 2023
    Date of Patent: October 3, 2023
    Assignee: JIANGSU UNIVERSITY
    Inventors: Quansheng Chen, Jizhong Wu, Huanhuan Li, Jingui Zhang, Hao Lin, Haihui Pan, Fuyun Wang, Yue Liang, Aijuan Ma, Tianyu Cao, Xiafei Xu, Huanke Hou
  • Publication number: 20230266249
    Abstract: A characteristic information extraction method of a small-molecule volatile substance, including: dividing a surface-enhanced Raman scattering (SERS) spectrum of the small-molecule volatile substance to obtain n wavelength subintervals, where n is a positive integer; sampling the n wavelength subintervals through weighted bootstrap sampling (WBS) to obtain Wwavelength subintervals, where W is a positive integer less than n; and screening the W wavelength subintervals to obtain desired wavelength subintervals. This application also provides a rapid detection method and a portable detection system of a small-molecule volatile substance.
    Type: Application
    Filed: April 28, 2023
    Publication date: August 24, 2023
    Inventors: Quansheng CHEN, Huanhuan LI, Qin OUYANG, Jiaji ZHU, Yi XU, Tianhui JIAO, Haihui PAN
  • Publication number: 20230265341
    Abstract: A method of preparing a dye-functionalized flexible upconversion-luminescence solid-phase sensor, including: preparation of upconversion-luminescence nanoparticles, preparation of an upconversion nanoparticle-doped solid-phase sensor, and preparation of a dye-functionalized flexible upconversion-luminescence solid-phase sensor. A method for detecting a gaseous pollutant is also provided, including: preparing a dye-functionalized flexible upconversion-luminescence solid-phase sensor through the above method; establishing a prediction model; and substituting a fluorescence intensity of a sample into the prediction model to calculate the gaseous pollutant concentration in the sample.
    Type: Application
    Filed: April 28, 2023
    Publication date: August 24, 2023
    Inventors: Quansheng CHEN, Jizhong WU, Huanhuan LI, Jingui ZHANG, Hao LIN, Haihui PAN, Fuyun WANG, Yue LIANG, Aijuan MA, Tianyu CAO, Xiafei XU, Huanke HOU
  • Patent number: 11635385
    Abstract: A method for fast extracting an organic pollutant in a complex system is disclosed, which includes following steps. A surface-enhanced Raman scattering (SERS) spectrum of an organic pollutant is divided to obtain P wavelength sub-intervals with overlapping regions. The P wavelength sub-intervals are screened to obtain ? wavelength sub-intervals. The ? wavelength sub-intervals are screened to obtain a required wavelength sub-interval. The required wavelength sub-interval is screened to obtain a required wavelength subset. A method and a system for fast detecting an organic pollutant in a complex system are also disclosed.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: April 25, 2023
    Assignees: JiMei University, Jiangsu University
    Inventors: Quansheng Chen, Huanhuan Li, Qin Ouyang, Jiaji Zhu, Yi Xu, Tianhui Jiao, Haihui Pan
  • Patent number: 11428741
    Abstract: A method and device for estimating an open circuit voltage of a battery based on a gas-liquid dynamic model, includes the following steps: deriving an undetermined equation for estimating the open circuit voltage according to a gas-liquid dynamic model; identifying the estimation equation parameters according to experimental data; designing a method for estimating the open circuit voltage according to the complete equation for estimating open circuit voltage and calculating to obtain an estimated value of the open circuit voltage. The estimation equation of open circuit voltage includes the battery temperature.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: August 30, 2022
    Assignee: JIANGSU UNIVERSITY
    Inventors: Biao Chen, Haobin Jiang, Huayang Sun, Huanhuan Li, Lei Hua
  • Patent number: 11358688
    Abstract: A method and a system for determining a safe under keel clearance of an ultra-large ship are provided. The method comprises: acquiring operation parameter values of the ship; obtaining fluid pressure according to the values; obtaining a squat force and a trim moment of the ship according to the pressure; establishing a mirror image model based on speed potential to establish a squat clearance calculation model for the ship; determining a half-wave rising height with above calculation model; obtaining draught and trim changes according to the squat force and the trim moment, to determine a maximum squat clearance of the hull; determining the safe under keel clearance; and controlling the squat clearance of the ship according to the safe under keel clearance of the ship, to avoid navigation dangers, and improve the loading rate.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: June 14, 2022
    Assignee: WUHAN UNIVERSITY OF TECHNOLOGY
    Inventors: Jingxian Liu, Yong Ma, Zhao Liu, Haisen Tong, Yanmin Xu, Huanhuan Li
  • Patent number: 11327297
    Abstract: Provided is a generation method for a programmable analog fringe pattern with an extended depth of field. A laser emits a laser beam. After focusing and collimation thereof with a collimating lens, a collimated Gaussian laser beam meeting requirements is obtained. The laser beam is reflected by a mirror once, passes through a round diaphragm and is incident on a MEMS scanning mirror. The beam is reflected by the MEMS scanning mirror to the surface of a tested object. The laser is controlled by a sinusoidal current signal generated by a drive board so as to sinusoidally modulate the brightness of the laser beam. The MEMS scanning mirror is stimulated by a drive signal generated by the drive board to turn two-dimensionally, so as to drive the laser beam to perform scanning, thus generating a fringe pattern image.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: May 10, 2022
    Assignee: Xi 'an Chishine Optoelectronics Technology Co., Ltd.
    Inventors: Xiang Zhou, Tao Yang, Rui Jin, Quan Li, Tao Liu, Li Ma, Junqi Huang, Huanhuan Li
  • Patent number: 11307258
    Abstract: A method and system for estimating open circuit voltage of lithium ion batteries with temperature input, that has the following steps: step 1 the undetermined equation for estimating open circuit voltage with temperature input is derived according to the gas-liquid dynamic model; step 2: the estimation equation parameters are identified according to the experimental data and put into the undetermined equation for estimating open circuit voltage in the step 1 to obtain a complete equation for estimating open circuit voltage; step 3: the method for estimating open circuit voltage with temperature input is designed according to the complete equation for estimating open circuit voltage.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: April 19, 2022
    Assignee: JIANGSU UNIVERSITY
    Inventors: Biao Chen, Haobin Jiang, Huayang Sun, Huanhuan Li, Lei Hua
  • Patent number: 11300620
    Abstract: A gas-liquid dynamic model-based accurate lithium-ion battery SOC estimation method, the gas-liquid dynamic model being a cylindrical closed container, a pipe and a valve that can be opened or closed being mounted at the top of the container, a liquid having a volume of Vw being held in the cylindrical container, and the remaining volume, V, being the volume of a gas having a pressure of P. According to the accurate SOC estimation method, a model, different from conventional RC equivalent circuit model and electrochemical model, is established from the perspective of a gas-liquid coexistence system. The method comprises the following steps: setting up an ideal gas state equation, a gas continuous motion equation, a gas-liquid dissolution equilibrium equation, etc.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: April 12, 2022
    Assignee: Jiangsu University
    Inventors: Biao Chen, Haobin Jiang, Huanhuan Li, Yaping Wang, Qian Zhao
  • Publication number: 20220042918
    Abstract: A method for fast extracting an organic pollutant in a complex system is disclosed, which includes following steps. A surface-enhanced Raman scattering (SERS) spectrum of an organic pollutant is divided to obtain P wavelength sub-intervals with overlapping regions. The P wavelength sub-intervals are screened to obtain ? wavelength sub-intervals. The ? wavelength sub-intervals are screened to obtain a required wavelength sub-interval. The required wavelength sub-interval is screened to obtain a required wavelength subset. A method and a system for fast detecting an organic pollutant in a complex system are also disclosed.
    Type: Application
    Filed: October 20, 2021
    Publication date: February 10, 2022
    Inventors: Quansheng CHEN, Huanhuan LI, Qin OUYANG, Jiaji ZHU, Yi XU, Tianhui JIAO, Haihui PAN
  • Publication number: 20220026357
    Abstract: The invention discloses a portable visible/near-infrared spectrum detection device, comprising a housing, a bottom plate, a screen support frame, a battery part on which a microprocessor is arranged, a detection part and a switch part, wherein the battery part, the detection part and the switch part are arranged in the housing; and the detection part comprises a spectrometer, a light source, a collimating mirror and the microprocessor. The device has the characteristics of rapidness, no damage and portability, and can realize rapid detection and early warning of food quality.
    Type: Application
    Filed: May 25, 2021
    Publication date: January 27, 2022
    Inventors: Qin Ouyang, Li Wang, Quansheng Chen, Zhiming Guo, Huanhuan Li, Jizhong Wu, Haihui Pan
  • Publication number: 20210405119
    Abstract: A method and device for estimating an open circuit voltage of a battery based on a gas-liquid dynamic model, includes the following steps: deriving an undetermined equation for estimating the open circuit voltage according to a gas-liquid dynamic model; identifying the estimation equation parameters according to experimental data; designing a method for estimating the open circuit voltage according to the complete equation for estimating open circuit voltage and calculating to obtain an estimated value of the open circuit voltage. The estimation equation of open circuit voltage includes the battery temperature.
    Type: Application
    Filed: March 29, 2019
    Publication date: December 30, 2021
    Inventors: Biao CHEN, Haobin Jiang, Huayang SUN, Huanhuan LI, Lei HUA
  • Patent number: 11105617
    Abstract: A hybrid light measurement method for measuring a three-dimensional profile comprises: Step 1 using a MEMS laser projector to realize projection of a laser stripe and a fringe pattern: and Step 2 performing matching to obtain a parallax, and incorporating a binocular stereo vision to perform reconstruction. The present disclosure employs MEMS projection technology to realize a hybrid measurement system capable of performing laser stripe measurement and fringe pattern measurement, thereby realizing quick measurement of three-dimensional profiles of objects having different surface properties. The present disclosure enables laser stripe measurement and fringe pattern measurement to be performed by the same measurement system without needing any additional hardware equipment. The projection device used in the present disclosure enables projection of multiple laser stripes, thereby increasing measurement precision and speed.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: August 31, 2021
    Assignee: XI 'AN CHISHINE OPTOELECTRONICS TECHNOLOGY CO., LTD
    Inventors: Xiang Zhou, Yuqin Li, Huanhuan Li, Quan Li, Tao Yang, Li Ma, Di Guo, Dong Yao
  • Publication number: 20210221484
    Abstract: A method and a system for determining a safe under keel clearance of an ultra-large ship are provided. The method comprises: acquiring operation parameter values of the ship; obtaining fluid pressure according to the values; obtaining a squat force and a trim moment of the ship according to the pressure; establishing a mirror image model based on speed potential to establish a squat clearance calculation model for the ship; determining a half-wave rising height with above calculation model; obtaining draught and trim changes according to the squat force and the trim moment, to determine a maximum squat clearance of the hull; determining the safe under keel clearance; and controlling the squat clearance of the ship according to the safe under keel clearance of the ship, to avoid navigation dangers, and improve the loading rate.
    Type: Application
    Filed: July 1, 2020
    Publication date: July 22, 2021
    Inventors: Jingxian LIU, Yong MA, Zhao LIU, Haisen TONG, Yanmin XU, Huanhuan LI