Patents by Inventor Huaping He

Huaping He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TUBERCULOSIS NUCLEIC ACIDS, POLYPEPTIDES AND IMMUNOGENIC COMPOSITIONS
    Publication number: 20100112008
    Abstract: The present invention provides transcriptionally active Mtb polynucleotides, recombinant Mtb peptides and polypeptides, and immunogenic Mtb antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines. In addition the invention provides diagnostic kits for Mtb.
    Type: Application
    Filed: October 27, 2009
    Publication date: May 6, 2010
    Inventors: David Roth, Huaping He
  • Tuberculosis nucleic acids, polypeptides and immunogenic compositions
    Patent number: 7608277
    Abstract: The present invention provides transcriptionally active Mtb polynucleotides, recombinant Mtb peptides and polypeptides, and immunogenic Mtb antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines. In addition, the invention provides diagnostic kits for Mtb.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: October 27, 2009
    Assignee: Gene Therapy Systems, Inc.
    Inventors: David Roth, Huaping He
  • Vaccinia virus nucleic acids, polypeptides and immunogenic compositions
    Publication number: 20060222658
    Abstract: The present invention provides transcriptionally active vaccinia virus polynucleotides, recombinant vaccinia virus polypeptides, and immunogenic vaccinia virus antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines.
    Type: Application
    Filed: November 30, 2005
    Publication date: October 5, 2006
    Inventors: David Roth, Huaping He
  • Protein arrays and methods and systems for producing the same
    Publication number: 20060224329
    Abstract: Methods of rapidly generating and analyzing a plurality of polypeptides are disclosed. More specifically, libraries and arrays of polypeptides are assayed in order to determine their individual immunogenic effect. Based on the immunogenic effect of polypeptides, specific subunit vaccines can be developed.
    Type: Application
    Filed: November 30, 2005
    Publication date: October 5, 2006
    Inventors: David Roth, Huaping He, Ben Good
  • Tuberculosis nucleic acids, polypeptides and immunogenic compositions
    Publication number: 20060140982
    Abstract: The present invention provides transcriptionally active Mtb polynucleotides, recombinant Mtb peptides and polypeptides, and immunogenic Mtb antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines. In addition the invention provides diagnostic kits for Mtb.
    Type: Application
    Filed: November 30, 2005
    Publication date: June 29, 2006
    Inventors: David Roth, Huaping He
  • Method for inhibition of phospholamban activity for the treatment of cardiac disease and heart failure
    Publication number: 20040121942
    Abstract: The present invention provides a method for the treatment of heart failure through the use of small peptide complexes and recombinant proteins which function to enhance contractility in failing hearts and reduce blood pressure in individuals with hypertension by inhibiting the interaction between phospholamban and sarcoplasmic reticulum Ca2+ ATPase (SERCA2a) within cardiomyocytes. In addition, a means is provided for the transport of such therapeutic agents into the cytoplasm and nucleus of cardiomyocytes.
    Type: Application
    Filed: November 10, 2003
    Publication date: June 24, 2004
    Inventors: Kenneth Chien, Wolfgang Dillman, Susumu Minamisawa, Huaping He, Masahiko Hoshijima, Markus Meyer, Christopher Scott, Yibin Wang, Gregg J. Silverman