Abstract: A boundary protection method and system of a radiation detection robot. The boundary protection method comprises: a first laser radar and a second laser radar are arranged diagonally, a first marking rod and a second marking rod are arranged diagonally; a boundary of an interlocking zone is defined by the first laser radar, the second laser radar, the first marking rod and the second marking rod; the object to be detected is placed in the interlocking zone; the radiation detection robot uses rays to detect the object to be detected in the interlocking zone; an early warning zone is provided outside the interlocking zone; wherein when it is detected that a person or object has intruded into the interlocking zone, the radiation detection robot stops emitting rays; and when it is detected that a person or object has intruded into the early warning zone, a warning is issued directly.

Abstract: Provided herein are inhibitors of ubiquitin-specific-processing Protease 1 (USP1), their pharmaceutical compositions, and methods of use for treating diseases or disorders, such as cancers described herein.

Abstract: A boundary protection method and system of a radiation detection robot. The boundary protection method comprises: a first laser radar and a second laser radar are arranged diagonally, a first marking rod and a second marking rod are arranged diagonally; a boundary of an interlocking zone is defined by the first laser radar, the second laser radar, the first marking rod and the second marking rod; the object to be detected is placed in the interlocking zone; the radiation detection robot uses rays to detect the object to be detected in the interlocking zone; an early warning zone is provided outside the interlocking zone; wherein when it is detected that a person or object has intruded into the interlocking zone, the radiation detection robot stops emitting rays; and when it is detected that a person or object has intruded into the early warning zone, a warning is issued directly.

Abstract: This invention discloses an expression vector system comprising a promoter recognized and regulated by a heat shock sigma factor of E. coli, especially ?32. Preferably, the promoter comprises the consensus sequence of E. coli heat shock promoters as shown in SEQ ID NO:1. Also disclosed are methods for producing proteins using the promoter under heat shock conditions. Furthermore, the present invention discloses a method for creating a sudden temperature shift in a cell culture which has been pre-cultured to reach an optimal condition and which temperature shift will allow optimal production of a recombinant protein under the control a heat shock promoter.

Abstract: This invention discloses an expression vector system comprising a promoter recognized and regulated by a heat shock sigma factor of E. coli, especially ?32 . Preferably, the promoter comprises the consensus sequence of E. coli heat shock promoters as shown in SEQ ID NO:1. Also disclosed are methods for producing proteins using the promoter under heat shock conditions. Furthermore, the present invention discloses a method for creating a sudden temperature shift in a cell culture which has been pre-cultured to reach an optimal condition and which temperature shift will allow optimal production of a recombinant protein under the control a heat shock promoter.