Abstract: An initiator system for self-curing plastic material comprises a) at least one salt of a dialklylbarbituric acid and/or an alkylcycloalkylbarbituric acid and/or alkylarylbarbituric acid and/or a cycloalkylarylbarbituric acid that is insoluble in methacrylate monomers; b) at least one heavy metal salt that is insoluble in methacrylate monomers; c) at least one halogenide ion donor that is insoluble in methacrylate monomers; and d) at least one acid that is soluble in methacrylate monomers. The initiator system can be used for the preparation of paste/paste, paste/powder, paste/liquid, powder/liquid, and liquid/liquid combinations for the production of medical plastic material and dental materials. Additionally, a bone cement composition containing the initiator system is described.

Abstract: A paste is provided from which bone cement can be formed, which is to the largest extent possible bubble-free and has a high impact strength. The paste includes (i) 15-50 weight percent of at least one mono-functional, hydrophobic methacrylic acid ester, (ii) 40-85 weight percent of at least one filler, (iii) 0.01-4 weight percent of at least one radical initiator soluble in the methacrylic acid ester (i) and having at least one peroxide group, (iv) 0.01-4 weight percent of at least one radical initiator soluble in the methacrylic acid ester (i) and having no peroxide groups, (v) 0.000001-3 weight percent of at least one accelerator soluble in the methacrylic acid ester (i) and capable of forming radicals from the radical initiators according to (iii) and (iv), (vi) 0.001-5 weight percent of at least one halide salt, and (vii) 0.2-3 weight percent of at least one cross-linking agent.

Abstract: A device is provided with which it is possible to produce poly(methyl methacrylate) bone-cement paste, which is degassed to the greatest extent possible, while avoiding large-volume mixing containers and large cement volumes contained therein. The device includes a tubular hollow body (10) having a first opening (30) on the input side and a second opening (20) on the output side, at least one rotatably-mounted shaft (40) arranged in the axial direction in the tubular hollow body (10), thread turns (50) arranged axially along the outer side of the shaft (40), wherein the shaft (40) has at least one section with thread turns (50) whose pitch decreases in the direction of the second opening (20), at least one stirring blade (60) arranged on the shaft (40), and rigid mixing elements (70) arranged on the inner side of the tubular hollow body (10).

Abstract: A surgical suture material with an antimicrobial surface is described, the surface exhibiting a coating containing a) at least one fatty acid, b) octenidine dichloride and/or dequalinium chloride and c) optionally oligomeric lactic acid esters. In addition, a process for coating surgical suture material is described which is characterized by the fact that the thread material is wetted with a homogeneous methanolic solution of octenidine dichloride and/or dequalinium chloride and subsequently the methanol is evaporated, a coating forming on the thread surface.

Abstract: A surgical suture material with an antimicrobial surface is described, the surface exhibiting a coating containing a) at least one fatty acid, b) octenidine dichloride and/or dequalinium chloride and c) optionally oligomeric lactic acid esters. In addition, a process for coating surgical suture material is described which is characterized by the fact that the thread material is wetted with a homogeneous methanolic solution of octenidine dichloride and/or dequalinium chloride and subsequently the methanol is evaporated, a coating forming on the thread surface.

Abstract: What is described are sporicidal compositions, in which hydrogen peroxide and at least one radical stabilizer are homogeneously dissolved in a methacrylate monomer or a mixture of methacrylate monomers, and the quantitative ratio of radical stabilizer to hydrogen peroxide is larger than or equal to 1 to 1. The sporicidal monomer/monomer mixture is usually used for producing single component bone cement pastes; two-component bone cement pastes or monomer solutions for polymethylmethacrylate bone cements that are based on cement powder and monomer liquid.

Abstract: The invention relates to a polymethylmethacrylate bone cement composition that contains polymethylmethacrylate, radio-opaquer, methylmethacrylate and/or alkylmethacrylates, and an initiator system and comprises, in addition, ferromagnetic and/or superparamagnetic particles of a particle size of up to maximally 500 ?m—which allows it to be heated by alternating magnetic fields—and further contains at least one biodegradable or biocompatible crystalline substance having a melting point in the range of 43-46° C. The cured cement can be used for local over-heating (hyperthermia) therapy in the absence of undesired temperature peaks.

Abstract: An initiator system for self-curing plastic material comprises a) at least one salt of a dialklylbarbituric acid and/or an alkylcycloalkylbarbituric acid and/or alkylarylbarbituric acid and/or a cycloalkylarylbarbituric acid that is insoluble in methacrylate monomers; b) at least one heavy metal salt that is insoluble in methacrylate monomers; c) at least one halogenide ion donor that is insoluble in methacrylate monomers; and d) at least one acid that is soluble in methacrylate monomers. The initiator system can be used for the preparation of paste/paste, paste/powder, paste/liquid, powder/liquid, and liquid/liquid combinations for the production of medical plastic material and dental materials. Additionally, a bone cement composition containing the initiator system is described.

Abstract: One-component bone cement pastes, containing: AI at least one methacrylate monomer that is suited for radical polymerisation; AII at least one polymer that is soluble in AI; AIII at least one particulate polymer that is insoluble in AI and has a particle size of less than 500 ?m; optionally AIV at least one initiator that can be activated, in particular at least one radical-forming initiator or at least one radical initiator that is soluble in AI and subject to thermal decomposition; optionally AV at least one electrically conductive radio-opaquer, in particular in the form of ferromagnetic particles; are well-suited, e.g.

Abstract: What is described is a paste-like PMMA bone cement that is characterised in that a paste-like component A, which is made up of one or more methacrylate monomers that can be distilled and polymerised by radical polymerisation, at least one polymer that is soluble in the methacrylate monomer/methacrylate monomers, at least one particulate polymer that is insoluble in the methacrylate monomer/methacrylate monomers and has a particle size of less than 500 ?m, and at least one radical initiator, and a paste-like component B, which is made up of one or more methacrylate monomers that can be distilled and polymerised by radical polymerisation, at least one polymer that is soluble in the methacrylate monomer/methacrylate monomers, at least one particulate polymer that is insoluble in the methacrylate monomer/methacrylate monomers and has a particle size of less than 500 ?m, and at least one accelerator, is present and in that a tack-free paste that cures by itself is generated upon mixing the paste-like components A

Abstract: What is described is a PMMA bone cement, containing at least one homopolymer or one copolymer having a glass transition temperature of more than 45° C., and at least one biocompatible elastomer that has a glass transition temperature of less than 37° C. and is soluble or insoluble in alkylmethacrylates and/or alkyldimethacrylates and/or alkyltrimethacrylates and/or alkyltetramethacrylates and has a residual monomer content of less than 5 percent. The PMMA bone cement is preferably used as self-curing plastic material for the fixation of primary total articular endoprostheses and revision total articular endoprostheses. Moreover, the PMMA bone cement can be used as self-curing filling material for vertebroplasty, kyphoplasty or femoral neck augmentation as well as for the production of temporary place-holders for two-stage revisions of total articular endoprostheses.

Abstract: This describes a polymethylmethacrylate bone cement that is characterized in that it contains a hydrolytically-degradable X-ray opaquer with a Mohs hardness equal to or less than 3 and a water solubility at room temperature of less than 4 g per liter. The polymethylmethacrylate bone cement is used as temporary placeholder.

Abstract: The invention relates to a PMMA revision bone cement having powder and liquid component, in which the powder component contains two or more granular antibiotics whose grain size distribution is equal in that the main screening fraction each of the individual antibiotics is in the same grain size range, in particular in the range of 100-250 ?m or 150-250 ?m.

Abstract: A surgical suture material with an antimicrobial surface is described, the surface exhibiting a coating containing a) at least one fatty acid, b) octenidine dichloride and/or dequalinium chloride and c) optionally oligomeric lactic acid esters. In addition, a process for coating surgical suture material is described which is characterized by the fact that the thread material is wetted with a homogeneous methanolic solution of octenidine dichloride and/or dequalinium chloride and subsequently the methanol is evaporated, a coating forming on the thread surface.