Patents by Inventor Hubert H.-M. Van Tol

Hubert H.-M. Van Tol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human D4 dopamine receptor and its uses
    Patent number: 5516683
    Abstract: The present invention is directed toward the isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor and alleleic variants thereof are provided by the invention. The invention particularly provides recombinant eukaryotic expression constructs capable of expressing the human D4 dopamine receptor at useful levels in cultures of transformed eukaryotic cells. The invention provides cultures of transformed eukaryotic cells which synthesize such useful amounts of human D4 dopamine receptor protein, and methods for characterizing novel psychotropic compounds using such cultures.
    Type: Grant
    Filed: April 29, 1993
    Date of Patent: May 14, 1996
    Assignee: State of Oregon, Acting by and Through the Oregon State Board of Higher Education on Behalf of the Oregon Health Sciences University a non-profit organization
    Inventors: David K. Grandy, James R. Bunzow, Olivier Civelli, Hubert H.-M. Van Tol