Patents by Inventor Hubert Henri-Marie Van Tol

Hubert Henri-Marie Van Tol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human dopamine receptor and its uses
    Patent number: 7053189
    Abstract: The present invention is directed toward antibodies, particularly monoclonal antibodies, which bind specifically to a novel human D4 dopamine receptor in sensitive and specific immunological assays useful for the detection, quantization, and characterization of human D4 dopamine and dopamine analogues.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: May 30, 2006
    Assignee: Oregon Health & Sciences University
    Inventors: Olivier Civelli, Hubert Henri-Marie Van Tol
  • Novel human dopamine receptor and its uses
    Publication number: 20030059845
    Abstract: The present invention is directed toward the isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor and alleleic variant thereof are provided by the invention. The invention also includes recombinant eukaryotic expression constructs capable of expressing the human D4 dopamine receptor in cultures of transformed eukaryotic cells. The invention provides cultures of transformed eukaryotic cells which synthesize the human D4 dopamine receptor, and methods for characterizing novel psychotropic compounds using such cultures.
    Type: Application
    Filed: August 20, 2002
    Publication date: March 27, 2003
    Inventors: Olivier Civelli, Hubert Henri-Marie Van Tol
  • Human dopamine receptor and uses
    Patent number: 6437114
    Abstract: The present invention is directed toward the isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor and alleleic variant thereof are provided by the invention. The invention also includes recombinant eukaryotic expression constructs capable of expressing the human D4 dopamine receptor in cultures of transformed eukaryotic cells. The invention provides cultures of transformed eukaryotic cells which synthesize the human D4 dopamine receptor, and methods for characterizing novel psychotropic compounds using such cultures.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: August 20, 2002
    Assignee: Oregon Health & Science University
    Inventors: Olivier Civelli, Hubert Henri-Marie Van Tol
  • Human dopamine receptor and its uses
    Patent number: 6203998
    Abstract: The present invention is directed toward isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor and alleleic variant thereof are provided by the invention. The invention also includes recombinant eukaryotic expression constructs capable of expressing the human D4 dopamine receptor in cultures of transformed eukaryotic cells. The invention provides cultures of transformed eukaryotic cells which synthesize the human D4 dopamine receptor, and methods for characterizing novel psychotropic compounds using such cultures.
    Type: Grant
    Filed: April 15, 1998
    Date of Patent: March 20, 2001
    Assignee: Oregon Health Sciences Univ.
    Inventors: Olivier Civelli, Hubert Henri-Marie Van Tol
  • Human dopamine receptor and its uses
    Patent number: 5883226
    Abstract: The present invention is directed toward the isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor and alleleic variant thereof are provided by the invention. The invention also includes recombinant eukaryotic expression constructs capable of expressing the human D4 dopamine receptor in cultures of transformed eukaryotic cells. The invention provides cultures of transformed eukaryotic cells which synthesize the human D4 dopamine receptor, and methods for characterizing novel psychotropic compounds using such cultures.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 16, 1999
    Assignee: State of Oregon
    Inventors: Olivier Civelli, Hubert Henri-Marie Van Tol