Patents by Inventor Hubert Hug

Hubert Hug has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dihydrochalcone purification process
    Patent number: 8993037
    Abstract: The present invention relates to an improved process for the preparation of an extract enriched in dihydrochalcones, and more specifically enriched in phlorizin, starting from a dry polyphenolic fraction originating from industrial apple processing. The invention also relates to a dihydrochal-cone extract obtainable by this process, and to a food or a nutraceutical product comprising a dihydrochalcone extract of the present invention.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: March 31, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Bettina Boehlendorf, Hubert Hug, Judith Kammerer, Claus Kilpert, Reinhold Carle
  • DIHYDROCHALCONE PURIFICATION PROCESS
    Publication number: 20130302504
    Abstract: The present invention relates to an improved process for the preparation of an extract enriched in dihydrochalcones, and more specifically enriched in phlorizin, starting from a polyphenolic fraction originating from industrial apple processing. The invention also relates to a dihydrochal-cone extract obtainable by this process, and to a food or a nutraceutical product comprising a dihydrochalcone extract of the present invention.
    Type: Application
    Filed: January 19, 2012
    Publication date: November 14, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Bettina Boehlendorf, Hubert Hug, Judith Kammerer, Claus Kilpert, Reinhold Carle
  • Use of 3,3?-diindolylmethane
    Patent number: 8420677
    Abstract: Use of DIM and/or its derivatives for prevention, treatment and/or delay of age-related hearing loss in mammals.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: April 16, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Hubert Hug, Bernd Mussler, Daniel Raederstorff, Ying Wang-Schmidt
  • NOVEL USE OF 3,3'-DIINDOLYLMETHANE
    Publication number: 20110190367
    Abstract: Use of DIM and/or its derivatives for prevention, treatment and/or delay of age-related hearing loss in mammals.
    Type: Application
    Filed: February 19, 2009
    Publication date: August 4, 2011
    Inventors: Hubert Hug, Bernd Mussler, Daniel Raederstorff, Ying Wang-Schmidt
  • Individual drug safety
    Publication number: 20050037366
    Abstract: The invention provides means to determine the predisposition of individuals to adverse drug reactions (ADRs). The methods are based on genotyping or parallelized enzyme and protein profiling or both. Parallelized enzyme activity profiling can be used for drug screening and development. As examples of the invention we show the prediction of adverse drug reactions of pulmonary hypertension patients by identifying genes and alleles linked to known ADRs and liver enzyme reaction profiling with ADR correlation.
    Type: Application
    Filed: August 14, 2003
    Publication date: February 17, 2005
    Inventors: Joseph Gut, Hubert Hug, Richard Schindler, Robert Dannecker, Dario Bagatto
  • Method of detecting the release of substances from cell organelles by means of flow cytometry
    Publication number: 20030092187
    Abstract: The invention is directed to a method of detecting the release of substances from cell organelles by means of flow cytometry, comprising the steps of: fixing cells to be studied; permeabilizing the outer cell membrane; staining the cells with a fluorochrome compound which binds specifically to at least one substance to be studied; measuring the individual cells by means of flow cytometry while stimulating the fluorochrome compound; and determining the fluorescent strength of the cells.
    Type: Application
    Filed: November 13, 2001
    Publication date: May 15, 2003
    Inventors: Karsten Stahnke, Hubert Hug, Klaus-Michael Debatin