Patents by Inventor Hubert Lam
Hubert Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230057310Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for treating subjects having cancer, are provided herein.Type: ApplicationFiled: September 27, 2019Publication date: February 23, 2023Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
-
Publication number: 20230041057Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for treating subjects having cancer, are provided herein.Type: ApplicationFiled: September 27, 2019Publication date: February 9, 2023Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
-
Publication number: 20210401722Abstract: Disclosed is a cosmetic composition that contains at least one polyhydroxyalkanoate (PHA) in the form of particles having an average diameter (d50) from 0.1 nm to 50 ?m. The PHA may comprise between 0.1% w/w and 30% w/w of the total cosmetic composition, and some embodiments may utilize between 1% w/w and 8% w/w. The composition may include a silicone external phase or may be in the form of a loose or packed powder. Various PHAs may be utilized, although advantageously, the PHA may have a chain length 1 and 8 carbons. In some embodiments, the PHA may be selected to have an oil absorption of between 60 to 150 grams of a desired oil per 100 grams of PHA, where the desired oil may be, e.g., sebum. Further, the composition may optionally include one or more pigments. In use, the composition may be applied to a user's skin or hair.Type: ApplicationFiled: June 26, 2020Publication date: December 30, 2021Applicant: L'ORÉALInventors: Hubert LAM, Phi Hoang DOAN, Mariko HASEBE
-
Publication number: 20210338725Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for treating subjects having cancer, are provided herein.Type: ApplicationFiled: April 2, 2021Publication date: November 4, 2021Inventors: Lisa K. McNeil, Victoria L. DeVault, James R. Perry, Hubert Lam, Adrienne V. Li
-
Publication number: 20210199644Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for identifying subjects for cancer therapy, are provided herein.Type: ApplicationFiled: October 30, 2020Publication date: July 1, 2021Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
-
Patent number: 10859566Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for identifying subjects for cancer therapy, are provided herein.Type: GrantFiled: March 20, 2018Date of Patent: December 8, 2020Assignee: GENOCEA BIOSCIENCES, INC.Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
-
Publication number: 20190099360Abstract: Pigmented cosmetic compositions capable of forming a multilayer structure after application to a keratinous material are provided, as well as methods of using same. Certain compositions comprise (a) Component A which comprises (i) about 0.01% to 60% by weight with respect to the total weight of the composition of at least one silicone- and/or hydrocarbon-containing film forming agent having at least one glass transition temperature which is lower than normal human body temperature; (ii) at least one pigment or filler, wherein the pigment or filler is surface-treated with a trialkoxyalkylsilane; and (b) Component B which comprises (i) about 0.01% to 90% by weight with respect to the total weight of the composition of one or more silicone compounds in amounts sufficient to achieve a viscosity of about 1,000 cSt to 10,000,000 cSt; wherein the Component A and Component B are immiscible.Type: ApplicationFiled: September 29, 2017Publication date: April 4, 2019Applicant: L'OREALInventors: ROSELIN ROSARIO-MELENDEZ, RITA JAKY EL-KHOURI, HUBERT LAM
-
Publication number: 20190072543Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for identifying subjects for cancer therapy, are provided herein.Type: ApplicationFiled: March 20, 2018Publication date: March 7, 2019Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
-
Patent number: 9956520Abstract: A carbon dioxide absorbent composition is described, including (i) a liquid, nonaqueous silicon-based material, functionalized with one or more groups that either reversibly react with CO2 or have a high-affinity for CO2, and (ii) a hydroxy-containing solvent that is capable of dissolving both the silicon-based material and a reaction product of the silicon-based material and CO2. The absorbent may be utilized in methods to reduce carbon dioxide in an exhaust gas, and finds particular utility in power plants.Type: GrantFiled: September 9, 2016Date of Patent: May 1, 2018Assignee: General Electric CompanyInventors: Robert James Perry, Grigorii Lev Soloveichik, Malgorzata Iwona Rubinsztajn, Michael Joseph O'Brien, Larry Neil Lewis, Tunchiao Hubert Lam, Sergei Kniajanski, Dan Hancu
-
Publication number: 20160375400Abstract: A carbon dioxide absorbent composition is described, including (i) a liquid, nonaqueous silicon-based material, functionalized with one or more groups that either reversibly react with CO2 or have a high-affinity for CO2, and (ii) a hydroxy-containing solvent that is capable of dissolving both the silicon-based material and a reaction product of the silicon-based material and CO2. The absorbent may be utilized in methods to reduce carbon dioxide in an exhaust gas, and finds particular utility in power plants.Type: ApplicationFiled: September 9, 2016Publication date: December 29, 2016Inventors: Robert James Perry, Grigorii Lev Soloveichik, Malgorzata Iwona Rubinsztajn, Michael Joseph O'Brien, Larry Neil Lewis, Tunchiao Hubert Lam, Sergei Kniajanski, Dan Hancu
-
Patent number: 9440182Abstract: A carbon dioxide absorbent composition is described, including (i) a liquid, nonaqueous silicon-based material, functionalized with one or more groups that either reversibly react with CO2 or have a high-affinity for CO2; and (ii) a hydroxy-containing solvent that is capable of dissolving both the silicon-based material and a reaction product of the silicon-based material and CO2. The absorbent may be utilized in methods to reduce carbon dioxide in an exhaust gas, and finds particular utility in power plants.Type: GrantFiled: December 21, 2011Date of Patent: September 13, 2016Assignee: General Electric CompanyInventors: Michael Joseph O'Brien, Robert James Perry, Tunchiao Hubert Lam, Grigorii Lev Soloveichik, Sergei Kniajanski, Larry Neil Lewis, Malgorzata Iwona Rubinsztajn, Dan Hancu
-
Publication number: 20120171095Abstract: A carbon dioxide absorbent composition is described, including (i) a liquid, nonaqueous silicon-based material, functionalized with one or more groups that either reversibly react with CO2 or have a high-affinity for CO2; and (ii) a hydroxy-containing solvent that is capable of dissolving both the silicon-based material and a reaction product of the silicon-based material and CO2. The absorbent may be utilized in methods to reduce carbon dioxide in an exhaust gas, and finds particular utility in power plants.Type: ApplicationFiled: December 21, 2011Publication date: July 5, 2012Applicant: GENERAL ELECTRIC COMPANYInventors: Michael Joseph O'Brien, Robert James Perry, Tunchiao Hubert Lam, Grigorii Lev Soloveichik, Sergei Kniajanski, Larry Neil Lewis, Malgorzata Iwona Rubinsztajn, Dan Hancu
-
Patent number: 8114382Abstract: The present invention relates to methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using a benzofuran compound or its radioisotope derivatives. In one embodiment a method of myelin detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the benzofuran compound, or a derivative of the compound, and determining myelination in the subject by detecting binding in the sample. In one embodiment, the invention provides a method of imaging myelinated tissue in a surgical field of mammalian tissue comprising the steps of contacting the surgical site with the benzofuran compound or a radioisotope derivative of the compound, and detecting binding in the surgical site.Type: GrantFiled: September 17, 2008Date of Patent: February 14, 2012Assignee: General Electric CompanyInventors: Cristina Abucay Tan Hehir, Stephen Johnson Lomnes, Kenneth Michael Fish, Tiberiu Mircea Siclovan, Michael Christopher Montalto, Tunchiao Hubert Lam
-
Publication number: 20110305635Abstract: The present invention relates to methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using a benzofuran compound or its radioisotope derivatives. In one embodiment a method of myelin detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the benzofuran compound, or a derivative of the compound, and determining myelination in the subject by detecting binding in the sample. In one embodiment, the invention provides a method of imaging myelinated tissue in a surgical field of mammalian tissue comprising the steps of contacting the surgical site with the benzofuran compound or a radioisotope derivative of the compound, and detecting binding in the surgical site.Type: ApplicationFiled: September 17, 2008Publication date: December 15, 2011Applicant: GENERAL ELECTRIC COMPANYInventors: Christina Abucay Tan Hehir, Stephen Johnson Lomnes, Kenneth Michael Fish, Tiberiu Mircea Siclovan, Michael Christopher Montalto, Tunchiao Hubert Lam
-
Patent number: 8030509Abstract: In accordance with one aspect, the present invention provides an amino-siloxane composition comprising at least one of structures I, II, III, IV or V said compositions being useful for the capture of carbon dioxide from gas streams such as power plant flue gases. In addition, the present invention provides methods of preparing the amino-siloxane compositions are provided. Also provided are methods for reducing the amount of carbon dioxide in a process stream employing the amino-siloxane compositions of the invention as species which react with carbon dioxide to form an adduct with carbon dioxide. The reaction of the amino-siloxane compositions provided by the present invention with carbon dioxide is reversible and thus, the method provides for multicycle use of said compositions.Type: GrantFiled: July 30, 2009Date of Patent: October 4, 2011Assignee: General Electric CompanyInventors: Robert James Perry, Larry Neil Lewis, Michael Joseph O'Brien, Grigorii Lev Soloveichik, Sergei Kniajanski, Tunchiao Hubert Lam, Julia Lam Lee, Malgorzata Iwona Rubinsztajn
-
Publication number: 20100158777Abstract: In accordance with one aspect, the present invention provides an amino-siloxane composition comprising at least one of structures I, II, III, IV or V said compositions being useful for the capture of carbon dioxide from gas streams such as power plant flue gases. In addition, the present invention provides methods of preparing the amino-siloxane compositions are provided. Also provided are methods for reducing the amount of carbon dioxide in a process stream employing the amino-siloxane compositions of the invention as species which react with carbon dioxide to form an adduct with carbon dioxide. The reaction of the amino-siloxane compositions provided by the present invention with carbon dioxide is reversible and thus, the method provides for multicycle use of said compositions.Type: ApplicationFiled: July 30, 2009Publication date: June 24, 2010Applicant: GENERAL ELECTRIC COMPANYInventors: Robert James Perry, Larry Neil Lewis, Michael Joseph O'Brien, Grigorii Lev Soloveichik, Sergei Kniajanski, Tunchiao Hubert Lam, Julia Lam Lee, Malgorzata Iwona Rubinsztajn
-
Publication number: 20100154639Abstract: A carbon dioxide absorbent comprising (i) a liquid, nonaqueous silicon-based material, functionalized with one or more groups that either reversibly react with CO2 or have a high-affinity for CO2 is provided and (ii) a hydroxy-containing solvent. The absorbent may be utilized in methods to reduce carbon dioxide in an exhaust gas, and finds particular utility in power plants.Type: ApplicationFiled: July 30, 2009Publication date: June 24, 2010Applicant: GENERAL ELECTRIC COMPANYInventors: Robert James Perry, Michael Joseph O'Brien, Tunchiao Hubert Lam, Grigorii Lev Soloveichik, Sergei Kniajanski, Larry Neil Lewis, Malgorzata Iwona Rubinsztajn, Dan Hancu
-
Patent number: 7727511Abstract: Provided herein are agents that bind to soluble beta-amyloid. Also provided are in vivo and in vitro methods for detecting soluble beta-amyloid in a sample that may include brain tissue.Type: GrantFiled: December 11, 2006Date of Patent: June 1, 2010Assignee: General Electric CompanyInventors: Tiberiu Mircea Siclovan, Michael Christopher Montalto, Tun Chiao Hubert Lam, Eric Dustin Agdeppa, Amy Casey Williams, Cristina Tan Hehir
-
Publication number: 20100068140Abstract: The present invention relates to methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using a benzofuran compound or its radioisotope derivatives. In one embodiment a method of myelin detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the benzofuran compound, or a derivative of the compound, and determining myelination in the subject by detecting binding in the sample. In one embodiment, the invention provides a method of imaging myelinated tissue in a surgical field of mammalian tissue comprising the steps of contacting the surgical site with the benzofuran compound or a radioisotope derivative of the compound, and detecting binding in the surgical site.Type: ApplicationFiled: September 17, 2008Publication date: March 18, 2010Applicant: GENERAL ELECTRIC COMPANYInventors: Christina Abucay Tan Hehir, Stephen Johnson Lomnes, Kenneth Michael Fish, Tiberiu Mircea Siclovan, Michael Christopher Montalto, Tunchiao Hubert Lam
-
Publication number: 20090162280Abstract: Agents, methods, and kits for qualitatively or quantitatively determining the presence of soluble A-beta in source of A-beta are provided, wherein the agents comprise the compound of formula III or the compound of formula III labeled with a signal generator.Type: ApplicationFiled: December 20, 2007Publication date: June 25, 2009Applicant: GENERAL ELECTRIC COMPANYInventors: Cristina Abucay Tan Hehir, Tiberiu Mircea Siclovan, Tunchiao Hubert Lam, Michael Christopher Montalto, Richard Waltz Harper, Warren Jaye Porter