Abstract: The present invention relates to a method for treating a liquid sample comprising at least one diagnostic assay reagent after use. The present invention further relates to a tablet, a purified liquid sample, a diagnostic assay reagent, a waste water treatment system, a kit and uses thereof for treating the said liquid sample.

Abstract: The present invention relates to a combination of elafibranor with either riboflavin or DHA as antiviral agent. The bacteriophage T4 titer on E. coli that is increased by elafibranor in comparison to an untreated control is reversed by the combination of elafibranor with riboflavin or elafibranor with DHA. Therefore, these combinations decrease adverse side effects of elafibranor on the gut microbiota.

Abstract: The present invention relates to systemic detoxification and chronic inflammation by using extract fractions of Laurus nobilis, that lead to a decrease of anti-inflammatory markers in human lung cell lines and the activation of the Nrf2 pathway, which is a crucial element in intracellular detoxification pathways, decreases the expression of inflammatory cytokines. Therefore, the extract can be used to reduce the adverse effects of air pollution generally (and especially of particulate air pollution), which includes: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues that come into contact with air borne particles.

Abstract: A diagnostic system and method and an interconnected laboratory system comprising clinical diagnostic systems are presented. The diagnostic system comprises a sample preparation module, a liquid chromatography (LC) separation module coupled to the sample preparation module via a sample preparation/LC interface, a mass spectrometer (MS) module coupled to the LC separation module via an LC/MS interface, and a result calculation module for identifying and/or quantifying analytes or substances of interest contained in the samples and passed through the LC separation and MS modules.

Abstract: The present invention relates to systemic detoxification by using extracts of Withania somnifera (ashwagandha) and its Nrf2-activating components withaferin-A, 12-deoxywithastramonolide, and Quresimine A. When ingested, the transcription factor Nrf2, which is a crucial element in intracellular detoxification pathways, leads to elimination of potentially toxic compounds. In parallel, the expression of inflammatory cytokines is decreased. Therefore, the extract can be used to reduce the adverse effects of air pollution generally (and especially of particulate air pollution), which includes: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues that come into contact with air borne particles.

Abstract: A diagnostic system and method and an interconnected laboratory system comprising clinical diagnostic systems are presented. The diagnostic system comprises a sample preparation module, a liquid chromatography (LC) separation module coupled to the sample preparation module via a sample preparation/LC interface, a mass spectrometer (MS) module coupled to the LC separation module via an LC/MS interface, and a result calculation module for identifying and/or quantifying analytes or substances of interest contained in the samples and passed through the LC separation and MS modules.

Abstract: A method for generating an entry for an electronic laboratory journal is presented. The method includes selecting a laboratory workflow specifying at least one action an operator has to carry out. The action involves one or more pieces of laboratory equipment. The method also comprises recording one or more images or videos of the action by the operator by using a camera associated with an augmented-reality device worn by the operator and generating an entry for an electronic laboratory journal based on the recorded one or more images or videos.

Abstract: A method for detecting analytes in a sample liquid is provided in which the sample liquid is subjected to a mixing treatment on a surface of a support having in particular immobilized reactants, wherein an in particular trough-like vessel with an essentially flat bottom as a support surface for the immobilized reactants is used as the vessel for the sample liquid. The sample liquid is moved relative to the immobilized reactants by an oscillating movement of the vessel during the mixing treatment in one direction, typically along a line or a curve. In addition, a device is provided for carrying out the method according to the present disclosure.

Abstract: The invention relates to a method for investigating the modulating effect of a test substance on a PKC?-dependent signal transduction pathway or for finding a PKC? modulator in a human or animal cell, including the steps (a) contacting the cell with the test substance or with the PKC? modulator; (b) where appropriate inducing the kinase activity of PKC?; (c) incubating the cell under conditions which bring about phosphorylation at least of a serine or threonine residue of PKC?; (d) where appropriate lysing the cell; and (e) determining the phosphorylation content of the at least one serine or threonine residue of PKC?.

Abstract: The apparatus includes a machine for subjecting a test-piece of superplastic material to a tensile test using a mobile member entraining one end of the test-piece and exerting traction on the test-piece. The mobile member is subjected to successive displacements whose speed and duration are controlled. The force applied to the test-piece and its length are measured as a function of time.