Patents by Inventor Hubert Rast

Hubert Rast has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7977484
    Abstract: The present invention relates to the trihydrate of pradofloxacin, to a process for its preparation and to antibacterial compositions comprising them.
    Type: Grant
    Filed: March 19, 2005
    Date of Patent: July 12, 2011
    Assignee: Bayer Animal Health GmbH
    Inventors: Hubert Rast, Iris Heep, Alfons Grunenberg, Werner Hallenbach, Jordi Benet-Buchholz
  • Publication number: 20080125458
    Abstract: The present invention relates to the trihydrate of pradofloxacin, to a process for its preparation and to antibacterial compositions comprising them.
    Type: Application
    Filed: March 19, 2005
    Publication date: May 29, 2008
    Applicant: BAYER HEALTHCARE AG
    Inventors: Hubert Rast, Iris Heep, Alfons Grunenberg, Werner Hallenbach, Jordi Benet-Buchholz
  • Patent number: 6995170
    Abstract: The present invention relates to a semi-hydrochloride of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid, to processes for its preparation and to antibacterial compositions comprising it. The semihydrochloride of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.
    Type: Grant
    Filed: November 15, 1999
    Date of Patent: February 7, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Hubert Rast
  • Patent number: 6664268
    Abstract: The present invention relates to a defined crystal modification of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (I), to processes for its preparation and to its use in pharmaceutical preparations. The crystal modification can be distinguished from other crystal modifications of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (I) by its characteristic X-ray powder diffractogram and its differential thermodiagram (see description).
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: December 16, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Werner Hallenbach, Hubert Rast
  • Patent number: 6649762
    Abstract: The present invention relates to a defined crystal modification of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (1), to processes for its preparation and to its use in pharmaceutical preparations. The crystal modification can be distinguished from other crystal modifications of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (1) by its characteristic X-ray powder diffractogram and its differential thermodiagram (see description).
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: November 18, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hubert Rast, Thomas Himmler
  • Patent number: 6492391
    Abstract: The present invention relates to a defined crystal modification of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, to processes for its preparation and to its use in pharmaceutical preparations. The crystal modification can be distinguished from other crystal modifications of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (I) by its characteristic X-ray powder diffractogram and its differential thermodiagram (see description).
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: December 10, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Hubert Rast
  • Patent number: 6436955
    Abstract: The present invention relates to a defined crystal modification of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0] nonan-8-yl)-6-fluoro-1, 4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (I), to processes for its preparation and to its use in pharmaceutical preparations. The crystal modification can be distinguished from other crystal modifications of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl )-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (I) by its characteristic X-ray powder diffractogram and its differential thermodiagram (see description).
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: August 20, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Werner Hallenbach, Hubert Rast
  • Patent number: 6114351
    Abstract: The present invention relates to new antibacterial compositions, in particular orally administrable compositions, based on N-oxides of saturated nitrogen-containing heterocycles which are substituted by quinolonecarboxylic acids or naphthyridonecarboxylic acids, and to new active compounds and their preparation.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: September 5, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hubert Rast, Martin Scheer, Werner Hallenbach
  • Patent number: 5808076
    Abstract: The present invention relates to the preparation of orally administrable formulations of quinolone- or naphthyridonecarboxylic acids by mixing quinolone- or naphthyridonecarboxylic acids as such or in the form of their water-soluble salts or derivatives, preferably in the form of their aqueous salt solutions, with embonic acid as such or in the form of its water-soluble salts or derivatives, preferably in the form of its aqueous salt solutions, in the presence of an excipient, optionally in the presence of auxiliaries, when using dry mixtures in the presence of water, and optionally converting the mixture obtained into further ready-to-use forms.
    Type: Grant
    Filed: December 6, 1996
    Date of Patent: September 15, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Oliver Vetter, Reinhold Lohr, Matthias Kuhn, Hubert Rast, Martin Scheer, Ernst Heinen, Francisco Cabrera
  • Patent number: 5152986
    Abstract: Known antibacterial quinolonecarboxylic acid derivatives such as ciprofloxacin are administered to animals in their food in the form of weak cation exchangers loaded therewith. The taste is much improved and the animals accept the material more readily.
    Type: Grant
    Filed: October 24, 1989
    Date of Patent: October 6, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Peter M. Lange, Alfred Mitschker, Arundev H. Naik, Hubert Rast, Martin Scheer, Herbert Voege
  • Patent number: 4666939
    Abstract: A stabilized febantel formulation comprising febantel, a water-miscible organic diluent and an acid, base or buffer salt in an amount such that when diluted 1:10 with water the formulation has a pH value of about 3 to 5. The formulation is far more stable than in the absence of the acid, base or buffer salt.
    Type: Grant
    Filed: March 20, 1985
    Date of Patent: May 19, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Herbert Voege, Hubert Rast