Abstract: A cannula fixation device includes a base having a platform; a subject-interface portion having an upper surface and a lower surface, the upper surface coupled to the base and the lower surface configured to be coupled to a subject; and a clip assembly configured to retain a portion of a cannula. The clip assembly is moveably coupled to the base such that the clip assembly can be selectively positioned in a first position relative to the base or a second position relative to the base.

Abstract: The integrity of a microporous membrane within a mass transfer device such as an oxygenator is tested simultaneously with applying a biocompatible surfactant to at least the blood-contact surface of the membrane. The membrane integrity test contacts both sides of the microporous membrane with a conductive fluid to establish an electrical circuit. An electrical signal is then applied to the circuit and a measurement is taken of the test voltage across an impedance in the circuit. The value of the test voltage is used to determine the conductivity and thus the integrity of the membrane. The biocompatible surfactant is mixed with the conductive fluid used in the electrical integrity test and has an affinity for the microporous membrane material so that a durable biocompatible coating is applied to at least a portion of the microporous membrane.

Abstract: Improved elastomeric materials useful for medical and therapeutic device applications, such as penetrable septa, are described. In one aspect, the materials are deeply cleaned with solvent to significantly lower levels of undesirable organics. In another aspect, internally lubricated elastomer compositions compatible for use in medical and therapeutic device applications are provided. The lubricating fluid is present in the composition from about 0.5% to 50% by weight, and is initially substantially homogeneously dispersed in the elastomer. The fluid can be integrated into the elastomer by a solvent infusion method. In another aspect an internally lubricated thermoplastic septum, having an appropriate hardness for resealability with multiple penetrations, is provided.