Patents by Inventor Hubertus Hohenblum

Hubertus Hohenblum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the manufacture of recombinant trypsin
    Patent number: 7351549
    Abstract: The present invention relates to a method for the manufacture and purification of recombinant trypsinogen and trypsin in E. coli and yeast, using high yield expression vectors with and without secretion leader sequences. The invention further relates to an improved method and apparatus for carrying out protein refolding specifically useful for processing trypsinogen that has accumulated intracellularly in the form of inclusion bodies.
    Type: Grant
    Filed: January 24, 2001
    Date of Patent: April 1, 2008
    Assignee: Polymun Scientific Immunbiologische Forschung GmbH
    Inventors: Diethard Mattanovich, Hermann Katinger, Hubertus Hohenblum, Stefan Naschberger, Robert Weik
  • Method for the manufacture of recombinant trypsin
    Publication number: 20030157634
    Abstract: The present invention relates to a method for the manufacture and purification of recombinant trypsinogen and trypsin in E. coli and yeast, using high yield expression vectors with and without secretion leader sequences. The invention further relates to an improved method and apparatus for carrying out protein refolding specifically useful for processing trypsinogen that has accumulated intracellularly in the form of inclusion bodies.
    Type: Application
    Filed: December 16, 2002
    Publication date: August 21, 2003
    Inventors: Diethard Mattanovich, Hermann Katinger, Hubertus Hohenblum, Stefan Naschberger, Robert Weik