Patents by Inventor Huda Akil

Huda Akil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF USING NCAM PEPTIDE MIMETICS
    Publication number: 20230055021
    Abstract: The present invention provides methods for treating or alleviating one or more symptoms of depression and/or anxiety in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject. The symptoms of depression and/or anxiety are typically observed in or associated with a neurological condition. The present invention also provides methods for treating a neurological condition such as a psychiatric disorder in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject.
    Type: Application
    Filed: March 15, 2022
    Publication date: February 23, 2023
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda Akil, Stanley J. Watson, Cortney Turner
  • METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF USING NCAM PEPTIDE MIMETICS
    Publication number: 20200399327
    Abstract: The present invention provides methods for treating or alleviating one or more symptoms of depression and/or anxiety in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject. The symptoms of depression and/or anxiety are typically observed in or associated with a neurological condition. The present invention also provides methods for treating a neurological condition such as a psychiatric disorder in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject.
    Type: Application
    Filed: February 7, 2020
    Publication date: December 24, 2020
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda AKIL, Stanley J. WATSON, Cortney TURNER
  • METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF USING NCAM PEPTIDE MIMETICS
    Publication number: 20190300587
    Abstract: The present invention provides methods for treating or alleviating one or more symptoms of depression and/or anxiety in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject. The symptoms of depression and/or anxiety are typically observed in or associated with a neurological condition. The present invention also provides methods for treating a neurological condition such as a psychiatric disorder in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject.
    Type: Application
    Filed: November 15, 2018
    Publication date: October 3, 2019
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda Akil, Stanley J. Watson, Cortney Turner
  • Method for decreasing depression-like behavior with connective tissue growth factor (CTGF) inhibitor
    Patent number: 10392435
    Abstract: The methods of the present invention are useful for determining whether an individual has or is at risk of developing an affective disorder by detecting the expression level of connective tissue growth factor (CTGF) in a biological sample. The methods of the present invention are also useful for identifying compounds that modulate (e.g., decrease) the expression level or activity of CTGF. The present invention further provides therapeutic methods that target CTGF for the treatment of an affective disorder.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: August 27, 2019
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda Akil, Stanley Watson, Cortney Turner
  • METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF USING NCAM PEPTIDE MIMETICS
    Publication number: 20180215799
    Abstract: The present invention provides methods for treating or alleviating one or more symptoms of depression and/or anxiety in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject. The symptoms of depression and/or anxiety are typically observed in or associated with a neurological condition. The present invention also provides methods for treating a neurological condition such as a psychiatric disorder in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject.
    Type: Application
    Filed: September 6, 2017
    Publication date: August 2, 2018
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda AKIL, Stanley J. WATSON, Cortney TURNER
  • METHODS FOR DIAGNOSING AND TREATING AFFECTIVE DISORDERS
    Publication number: 20180208649
    Abstract: The methods of the present invention are useful for determining whether an individual has or is at risk of developing an affective disorder by detecting the expression level of connective tissue growth factor (CTGF) in a biological sample. The methods of the present invention are also useful for identifying compounds that modulate (e.g., decrease) the expression level or activity of CTGF. The present invention further provides therapeutic methods that target CTGF for the treatment of an affective disorder.
    Type: Application
    Filed: December 6, 2017
    Publication date: July 26, 2018
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda AKIL, Stanley WATSON, Cortney TURNER
  • Administration of FGF9 for treatment and prevention of major depression
    Patent number: 9957568
    Abstract: The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: May 1, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda Akil, Stanley J. Watson, Cortney Turner
  • GENES AND PATHWAYS DIFFERENTIALLY EXPRESSED IN BIPOLAR DISORDER AND/OR MAJOR DEPRESSIVE DISORDER
    Publication number: 20170211144
    Abstract: The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.
    Type: Application
    Filed: September 20, 2016
    Publication date: July 27, 2017
    Inventors: Huda AKIL, Stanley J. WATSON, Cortney TURNER
  • Administration of FGF9 for treatment of anxiety
    Patent number: 9486499
    Abstract: The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: November 8, 2016
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Huda Akil, Stanley J. Watson, Cortney Turner
  • Methods for treating depression using NCAM peptide mimetics
    Patent number: 9234242
    Abstract: The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: January 12, 2016
    Assignee: THE BOARD OF THE TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Huda Akil, Stanley J. Watson, Cortney Turner, William E. Bunny, Edward G. Jones, Richard M. Myers, Alan F. Schatzberg
  • METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF USING NCAM PEPTIDE MIMETICS
    Publication number: 20150203545
    Abstract: The present invention provides methods for treating or alleviating one or more symptoms of depression and/or anxiety in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject. The symptoms of depression and/or anxiety are typically observed in or associated with a neurological condition. The present invention also provides methods for treating a neurological condition such as a psychiatric disorder in a subject comprising administering an effective amount of an NCAM peptide mimetic to the subject.
    Type: Application
    Filed: December 3, 2014
    Publication date: July 23, 2015
    Inventors: Huda Akil, Stanley Watson, Cortney Turner
  • Administration of FGF2 for treamtent of anxiety
    Patent number: 8415298
    Abstract: The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.
    Type: Grant
    Filed: June 21, 2005
    Date of Patent: April 9, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University of Stanford
    Inventors: Huda Akil, William E. Bunney, Jr., Prabhakara V. Choudary, Simon J. Evans, Edward G. Jones, Jun Li, Juan F. Lopez, David M. Lyons, Margherita Molnar, Richard M. Myers, Alan F. Schatzberg, Richard Stein, Robert C. Thompson, Hiroaki Tomita, Marquis P. Vawter, Stanley J. Watson
  • METHODS FOR TREATING DEPRESSION USING NCAM PEPTIDE MIMETICS
    Publication number: 20120277159
    Abstract: The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
    Type: Application
    Filed: March 27, 2012
    Publication date: November 1, 2012
    Applicant: Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda Akil, Stanley Watson, Cortney Turner, William Bunney, Edward Jones, Richard Myers, Alan Schatzberg
  • COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING MENTAL DISORDERS
    Publication number: 20110224144
    Abstract: The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
    Type: Application
    Filed: October 12, 2010
    Publication date: September 15, 2011
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda Akil, Mary Atz, William E. Bunney, JR., Prabhakara V. Choudary, Simon J. Evans, Edward G. Jones, Jun Li, Juan F. Lopez, Richard Myers, Robert C. Thompson, Hiroaki Tomita, Marquis P. Vawter, Stanley Watson
  • SNP DETECTION AND OTHER METHODS FOR CHARACTERIZING AND TREATING BIPOLAR DISORDER AND OTHER AILMENTS
    Publication number: 20110104674
    Abstract: The present application relates to the use of SNPs and differential exon expression to characterize, diagnose or treat bipolar disorder and other mental illnesses, such as major depressive disorder and schizophrenia.
    Type: Application
    Filed: April 20, 2010
    Publication date: May 5, 2011
    Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: HUDA AKIL, STANLEY J. WATSON, SIMON J. EVANS, CORTNEY TURNER, RENE BERNARD, ILAN KERMAN, ROBERT THOMPSON, MARGIT BURMEISTER, LAURA J. SCOTT, FAN MENG, MICHAEL BOEHNKE, WILLIAM BUNNEY, MARQUIS VAWTER, EDWARD JONES, PRABHAKARA V. CHOUDARY, RICHARD MYERS, ALAN SCHATZBERG, JUN LI, DEVIN ABSHER
  • FGF9-RELATED METHODS FOR TREATING ANXIETY
    Publication number: 20110092433
    Abstract: The present application relates to the treatment of anxiety in a subject. The invention provides novel diagnostic markers and assays, as well as agents and compounds useful for treating patients who suffer from mental illnesses and anxiety disorders.
    Type: Application
    Filed: April 29, 2010
    Publication date: April 21, 2011
    Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: HUDA AKIL, STANLEY WATSON, CORTNEY TURNER
  • COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING NEUROPSYCHIATRIC DISORDERS
    Publication number: 20110014610
    Abstract: The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
    Type: Application
    Filed: February 5, 2010
    Publication date: January 20, 2011
    Applicant: Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda Akil, Mary Atz, William E. Bunney, JR., William Byerley, Kathleen Casey, Prabhakara V. Choudary, Simon J. Evans, Edward G. Jones, Jun Li, Juan F. Lopez, Richard M. Myers, Brandi Rollins, Robert C. Thompson, Hiroaki Tomita, Marquis P. Vawter, Stanley J. Watson
  • Compositions and methods for diagnosing and treating neuropsychiatric disorders
    Patent number: 7687235
    Abstract: The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: March 30, 2010
    Assignee: The Board of Regents of the Leland Stanford Junior University
    Inventors: Huda Akil, Mary Atz, William E. Bunney, Jr., William Byerley, Kathleen Casey, Prabhakara V. Choudary, Simon J. Evans, Edward G. Jones, Jun Li, Juan F. Lopez, Richard M. Myers, Brandi Rollins, Robert C. Thompson, Hiroaki Tomita, Marquis P. Vawter, Stanley J. Watson
  • FGF2-RELATED METHODS FOR DIAGNOSING AND TREATING DEPRESSION
    Publication number: 20090233842
    Abstract: The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
    Type: Application
    Filed: November 13, 2006
    Publication date: September 17, 2009
    Applicant: Prtzker Neuropsychiatric Research Fund LLC
    Inventors: Huda Akil, Stanley J. Watson, Simon J. Evans, Cortney Turner, Rene Bernard, Ilan Kerman, Robert C. Thompson, Margit Burmeister, Laura J. Scott, Fan Meng, Michael Boehnke, William E. Bunney, JR., Marquis P. Vawter, Edward G. Jones, Prabhakara V. Choudary, Richard M. Myers, Alan F. Schatzberg, Jun Li, Devin Absher, Hiroaki Tomita
  • Compositions and methods for diagnosis and treating mood disorders
    Publication number: 20090117565
    Abstract: The present invention provides methods for diagnosing mental disorders such as mood disorders, including bipolar disorder I and II and major depression; The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
    Type: Application
    Filed: May 21, 2008
    Publication date: May 7, 2009
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huda Akil, William E. Bunney, JR., Prabhakara V. Choudary, Simon J. Evans, Edward G. Jones, Jun Li, Juan F. Lopez, Robert C. Thompson, Richard Myers, Hiroaki Tomita, Marquis P. Vawter, Stanley Watson