Abstract: The present invention relates to a carrier conjugate comprising at least one dodecin protein unit conjugated with at least one hapten and/or immunogenic and/or enzymatically active moiety. Further, the invention relates to a method for producing said conjugate and a method for producing antibodies that specifically binds to a hapten and/or immunogenic moiety of the conjugate, and to a method for performing enzymatic or diagnostic assays in vitro using said conjugate. Moreover, the invention relates to the use of said conjugate for producing antibodies that specifically bind to the epitope or epitopes contained in the moiety of said conjugate and use of said conjugate for performing enzymatic or diagnostic assays in vitro.

Abstract: The present invention is directed at stabilizing linear polynucleotides against exonucleolytic attack. Adding to both ends of a double-stranded linear DNA a target sequence for a DNA-binding protein the double-stranded linear DNA with the two added target sequences has an increased stability against exonucleolytic attack when contacted with the DNA-binding protein.