Patents by Inventor Huey Wen Lee

Huey Wen Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FIBROTIC TREATMENT
    Publication number: 20240084308
    Abstract: The present invention relates to compositions, methods and kits for the treatment of fibrosis. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment of cardiac fibrosis. The invention provides a method of treating fibrosis in an individual comprising administering an inhibitor of insulin-regulated aminopeptidase (IRAP), thereby treating fibrosis.
    Type: Application
    Filed: October 26, 2023
    Publication date: March 14, 2024
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee
  • Fibrotic treatment
    Patent number: 11834663
    Abstract: The present invention relates to compositions, methods and kits for the treatment of fibrosis. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment of cardiac fibrosis. The invention provides a method of treating fibrosis in an individual comprising administering an inhibitor of insulin-regulated aminopeptidase (IRAP), thereby treating fibrosis.
    Type: Grant
    Filed: July 1, 2021
    Date of Patent: December 5, 2023
    Assignee: MONASH UNIVERSITY
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee
  • FIBROTIC TREATMENT
    Publication number: 20210340547
    Abstract: The present invention relates to compositions, methods and kits for the treatment of fibrosis. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment of cardiac fibrosis. The invention provides a method of treating fibrosis in an individual comprising administering an inhibitor of insulin-regulated aminopeptidase (IRAP), thereby treating fibrosis.
    Type: Application
    Filed: July 1, 2021
    Publication date: November 4, 2021
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee
  • Fibrotic treatment
    Patent number: 11078488
    Abstract: The present invention relates to compositions, methods and kits for the treatment of fibrosis. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment of cardiac fibrosis. The invention provides a method of treating fibrosis in an individual comprising administering an inhibitor of insulin-regulated aminopeptidase (IRAP), thereby treating fibrosis.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: August 3, 2021
    Assignee: MONASH UNIVERSITY
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee
  • FIBROTIC TREATMENT
    Publication number: 20200362354
    Abstract: The present invention relates to compositions, methods and kits for the treatment of fibrosis. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment of cardiac fibrosis. The invention provides a method of treating fibrosis in an individual comprising administering an inhibitor of insulin-regulated aminopeptidase (IRAP), thereby treating fibrosis.
    Type: Application
    Filed: August 4, 2020
    Publication date: November 19, 2020
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee
  • Fibrotic treatment
    Patent number: 10787668
    Abstract: The present invention relates to a method for the treatment of fibrosis, in particular cardiac fibrosis, comprising the administration of an inhibitor of insulin-regulated aminopeptidase (IRAP). Preferable the IRAP inhibitor is chosen from the group including HFI-419, HA-08, AL-40, HFI-437, Val-Tyr-Ile-His-Pro-Phe (otherwise known as angiotensin IV or ANG IV), c[Cys-Tyr-Cys]-His-Pro-Phe, and c[Hcy-Tyr-Hcy]-His-Pro-Phe.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: September 29, 2020
    Assignee: MONASH UNIVERSITY
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee
  • FIBROTIC TREATMENT
    Publication number: 20190249179
    Abstract: The present invention relates to a method for the treatment of fibrosis, in particular cardiac fibrosis, comprising the administration of an inhibitor of insulin-regulated aminopeptidase (IRAP). Preferable the IRAP inhibitor is chosen from the group including HFI-419, HA-08, AL-40, HFI-437, Val-Tyr-Ile-His-Pro-Phe (otherwise known as angiotensin IV or ANG IV), c[Cys-Tyr-Cys]-His-Pro-Phe, and c[Hcy-Tyr-Hcy]-His-Pro-Phe.
    Type: Application
    Filed: September 6, 2018
    Publication date: August 15, 2019
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee
  • Fibrotic treatment
    Patent number: 10100311
    Abstract: The present invention relates to a method for the treatment of fibrosis, in particular cardiac fibrosis, comprising the administration of an inhibitor of insulin-regulated aminopeptidase (IRAP). Preferable the IRAP inhibitor is chosen from the group including HFI-419, HA-08, AL-40, HFI-437, Val-Tyr-Ile-His-Pro-Phe (otherwise known as angiotensin IV or ANG IV), c[Cys-Tyr-Cys]-His-Pro-Phe, and c[Hcy-Tyr-Hcy]-His-Pro-Phe.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: October 16, 2018
    Assignee: MONASH UNIVERSITY
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee
  • FIBROTIC TREATMENT
    Publication number: 20180223287
    Abstract: The present invention relates to a method for the treatment of fibrosis, in particular cardiac fibrosis, comprising the administration of an inhibitor of insulin-regulated aminopeptidase (IRAP). Preferable the IRAP inhibitor is chosen from the group including HFI-419, HA-08, AL-40, HFI-437, Val-Tyr-Ile-His-Pro-Phe (otherwise known as angiotensin IV or ANG IV), c[Cys-Tyr-Cys]-His-Pro-Phe, and c[Hcy-Tyr-Hcy]-His-Pro-Phe.
    Type: Application
    Filed: July 29, 2016
    Publication date: August 9, 2018
    Inventors: Siew Yeen Chai, Robert Widdop, Tracey Gaspari, Huey Wen Lee