Patents by Inventor Hugh A. George

Hugh A. George has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and system for analyzing calcium transients in coupled cells
    Patent number: 8666676
    Abstract: A system and method are provided for measuring dynamic phenomena in a biological, chemical or physical sample, including the measurement of Ca2+ transients in a living system. The system and method include measuring dynamic phenomena in an in vitro cardiac cell culture system. Computing system environments and computing systems for implementing the method are provided.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: March 4, 2014
    Assignee: University College Cardiff Consultants Limited
    Inventors: Christopher Hugh George, Steven Roger Barberini-Jammaers, Nicole Cherie Silvester
  • METHOD AND SYSTEM OF ANALYZING DYNAMIC PHENOMENA
    Publication number: 20120109532
    Abstract: A system and method are provided for measuring dynamic phenomena in a biological, chemical or physical sample, including the measurement of Ca2+ transients in a living system. The system and method include measuring dynamic phenomena in an in vitro cardiac cell culture system. Computing system environments and computing systems for implementing the method are provided.
    Type: Application
    Filed: November 28, 2011
    Publication date: May 3, 2012
    Inventors: Christopher Hugh George, Steven Roger Barberini-Jammaers, Nicole Cherie Silvester
  • DNA encoding human papilloma virus type 18
    Patent number: 6908615
    Abstract: The present invention is directed to DNA molecules encoding purified human papillomavirus type 18 and derivatives thereof.
    Type: Grant
    Filed: March 18, 1996
    Date of Patent: June 21, 2005
    Assignee: Merck & Co., Inc.
    Inventors: Kathryn J. Hofmann, Kathrin U. Jansen, Michael P. Neeper, Joseph G. Joyce, Hugh A. George
  • Synthetic HPV6/11 hybrid L1 DNA encoding human papillomavirus type 11 L1 protein
    Patent number: 6159729
    Abstract: The present invention is directed to a synthetic DNA molecule encoding purified human papillomavirus type 11 L1 protein and derivatives thereof.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: December 12, 2000
    Assignee: Merck & Co., Ltd.
    Inventors: Kathryn J. Hofmann, Kathrin U. Jansen, Michael P. Neeper, Joseph G. Joyce, Hugh A. George, E. Dale Lehman
  • Recombinant papillomavirus vaccines
    Patent number: 5888516
    Abstract: Recombinant expression vectors encoding the L1 and L2 proteins of papillomavirus, methods of making and using the recombinant proteins and purified virus-like particles comprised of the recombinant proteins are provided.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: March 30, 1999
    Assignee: Merck & Co. Inc.
    Inventors: Kathrin U. Jansen, James C. Cook, III, Hugh A. George, Kathryn J. Hofmann, Joseph G. Joyce, Ernest Dale Lehman, Henry Z. Markus, Mark Rosolowsky, Loren S. Schultz
  • Recombinant human papillomavirus type 18 vaccine
    Patent number: 5820870
    Abstract: The present invention is directed to vaccines for human papillomavirus type 18 and derivatives thereof.
    Type: Grant
    Filed: March 22, 1995
    Date of Patent: October 13, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Joseph G. Joyce, Hugh A. George, Kathryn J. Hofman, Kathrin U. Jansen, Michael P. Neeper
  • Production of recombinant human papillomavirus type II protein utilizing papillomavirus 6/11 hybrid DNA
    Patent number: 5821087
    Abstract: The present invention is directed to a recombinant human papillomavirus type 11 L1 protein encoded by a synthetic DNA molecule and methods of making and using the protein.
    Type: Grant
    Filed: September 11, 1996
    Date of Patent: October 13, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Robert Lowe, Joseph G. Joyce, Hugh A. George, Kathryn J. Hofmann, Kathrin U. Jansen, E. Dale Lehman, Michael P. Neeper
  • Culture medium for Saccharomyces cerevisiae
    Patent number: 5795771
    Abstract: A synthetic culture medium for the growth of recombinant yeast and the production of recombinant proteins. The medium is useful for the growth of Saccharomyces cerevisiae which comprises per liter about 10 g ammonium sulfate, about 10 g potassium phosphate, about 0.5 g calcium chloride, about 0.5 g sodium chloride, about 3 g magnesium sulfate, about 0.25 g L-tyrosine, about 0.1 g choline, between about 1 and about 100 g carbon source, between about 50-150 mL amino acid cocktail, about 30 mL vitamin solution, about 20 mL trace element solution and about 0.3 mL UCON LB-625 antifoaming agent. Further, the vitamin solution contains biotin, pantothenate, myo-inositol, pyridoxine and thiamine.
    Type: Grant
    Filed: April 8, 1996
    Date of Patent: August 18, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Hugh George, Wayne K. Herber