Patents by Inventor Hugh Alfred Burgoon

Hugh Alfred Burgoon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of preparing 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds
    Patent number: 8575362
    Abstract: Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: November 5, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Mark S. Bednarz, Hugh Alfred Burgoon, Jr., Shinya Iimura, Ramanaiah C. Kanamarlapudi, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang
  • Compounds useful in the preparation of tryptophan hydroxylase inhibitors
    Patent number: 8450532
    Abstract: Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: May 28, 2013
  • LIMK2 inhibitors, compositions comprising them, and methods of their use
    Patent number: 8450332
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: May 28, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hugh Alfred Burgoon, Nicole Cathleen Goodwin, Bryce Alden Harrison, Jason Patrick Healy, Ying Liu, Ross Mabon, Brett Marinelli, David Brent Rawlins, Dennis Stewart Rice, Norris Andrew Whitlock
  • LIMK2 INHIBITORS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE
    Publication number: 20120329818
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Application
    Filed: June 1, 2012
    Publication date: December 27, 2012
    Inventors: Hugh Alfred BURGOON, Nicole Cathleen GOODWIN, Bryce Alden HARRISON, Jason Patrick HEALY, Ying LIU, Ross MABON, Brett MARINELLI, David Brent RAWLINS, Dennis Stewart RICE, Norris Andrew WHITLOCK
  • LIMK2 inhibitors, compositions comprising them, and methods of their use
    Patent number: 8193202
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: June 5, 2012
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hugh Alfred Burgoon, Nicole Cathleen Goodwin, Bryce Alden Harrison, Jason Patrick Healy, Ying Liu, Ross Mabon, Brett Marinelli, David Brent Rawlins, Dennis Stewart Rice, Norris Andrew Whitlock
  • METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS
    Publication number: 20110301349
    Abstract: Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
    Type: Application
    Filed: June 15, 2011
    Publication date: December 8, 2011
    Inventors: Mark S. Bednarz, Hugh Alfred Burgoon, JR., Shinya Iimura, Ramanaiah C. Kanamarlapudi, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang
  • Solid forms of (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol and methods of their use
    Patent number: 7998994
    Abstract: Solid forms of (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol and hydrates thereof are disclosed, as well as compositions comprising them and methods of their use.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: August 16, 2011
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hugh Alfred Burgoon, Suzanne Marie Buttar, Christopher Stephen Frampton
  • 1-phenyl-1H-pyrazole-based compounds
    Patent number: 7968729
    Abstract: Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: June 28, 2011
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Mark S. Bednarz, Hugh Alfred Burgoon, Jr., Shinya Iimura, Ramanaiah C. Kanamarlapudi, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang
  • COMPOUNDS USEFUL IN THE PREPARATION OF TRYPTOPHAN HYDRROXYLASE INHIBITORS
    Publication number: 20110130564
    Abstract: Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g.
    Type: Application
    Filed: February 10, 2011
    Publication date: June 2, 2011
  • Synthesis of piperazines, piperidines and related compounds
    Patent number: 7919618
    Abstract: Novel methods of synthesizing piperazines, piperidines and related compounds are disclosed, as are compounds useful for their preparation.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: April 5, 2011
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hugh Alfred Burgoon, Jr., Ramanaiah C. Kanamarlapudi, Wenxue Wu
  • Process for the preparation of substituted phenylalanines
    Patent number: 7897763
    Abstract: Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: March 1, 2011
  • Process for the preparation of substituted phenylalanines
    Patent number: 7855291
    Abstract: Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: December 21, 2010
  • 1-PHENYL-1H-PYRAZOLE-BASED COMPOUNDS
    Publication number: 20100240906
    Abstract: Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
    Type: Application
    Filed: March 26, 2010
    Publication date: September 23, 2010
    Inventors: Mark S. Bednarz, Hugh Alfred Burgoon, JR., Shinya Iimura, Ramanaiah C. Kanamarlapudi, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang
  • SOLID FORMS OF (1R,2S,3R)-1-(2-(ISOXAZOL-3-YL)-1H-IMIDAZOL-4-YL)BUTANE-1,2,3,4-TETRAOL AND METHODS OF THEIR USE
    Publication number: 20090318516
    Abstract: Solid forms of (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol and hydrates thereof are disclosed, as well as compositions comprising them and methods of their use.
    Type: Application
    Filed: June 16, 2009
    Publication date: December 24, 2009
    Inventors: Hugh Alfred Burgoon, Suzanne Marie Buttar, Christopher Stephen Frampton
  • LIMK2 INHIBITORS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE
    Publication number: 20090264450
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Application
    Filed: April 20, 2009
    Publication date: October 22, 2009
    Inventors: Hugh Alfred Burgoon, Nicole Cathleen Goodwin, Bryce Alden Harrison, Jason Patrick Healy, Ying Liu, Ross Mabon, Brett Marinelli, David Brent Rawlins, Dennis Stewart Rice, Norris Andrew Whitlock
  • PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLALANINES
    Publication number: 20090118505
    Abstract: Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g.
    Type: Application
    Filed: October 24, 2008
    Publication date: May 7, 2009
  • METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS
    Publication number: 20090062540
    Abstract: Methods useful for preparing compounds of formula I: and salts thereof are disclosed. Also disclosed are intermediates useful in the preparation of such compounds.
    Type: Application
    Filed: August 22, 2008
    Publication date: March 5, 2009
    Inventors: Mark S. Bednarz, Hugh Alfred Burgoon, JR., Shinya Iimura, Ramanaiah C. Kanamarlapudi, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang
  • Process for the preparation of substituted phenylalanines
    Publication number: 20090048280
    Abstract: Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g.
    Type: Application
    Filed: December 28, 2006
    Publication date: February 19, 2009
  • Synthesis of piperazines, piperidines and related compounds
    Publication number: 20080177070
    Abstract: Novel methods of synthesizing piperazines, piperidines and related compounds are disclosed, as are compounds useful for their preparation.
    Type: Application
    Filed: August 2, 2007
    Publication date: July 24, 2008
    Inventors: Hugh Alfred Burgoon, Ramanaiah C. Kanamarlapudi, Wenxue Wu