Patents by Inventor Hugh Daniels
Hugh Daniels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110064785Abstract: Methods, systems, and apparatuses for nanomaterial-enhanced platelet binding and hemostatic medical devices are provided. Hemostatic materials and structures are provided that induce platelet binding, including platelet binding and the coagulation of blood at a wound/opening caused by trauma, a surgical procedure, ulceration, or other cause. Example embodiments include platelet binding devices, hemostatic bandages, hemostatic plugs, and hemostatic formulations. The hemostatic materials and structures may incorporate nanostructures and/or further hemostatic elements such as polymers, silicon nanofibers, silicon dioxide nanofibers, and/or glass beads into a highly absorbent, gelling scaffold. The hemostatic materials and structures may be resorbable.Type: ApplicationFiled: March 9, 2010Publication date: March 17, 2011Applicant: Nanosys, Inc.Inventors: R. Hugh Daniels, Esther Li, Erica J. Rogers
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Patent number: 7888292Abstract: Methods of detecting a component of interest, a change in charge, a pH, a cellular response using nanosensors are provided. Nanosensors, including nanowires and nanowire arrays comprising functionalized and/or non-functionalized nanowires are provided. Nanosensors are used for detection in cellular fragmentation, multiple concentration analysis, glucose detection, and intracellular analysis.Type: GrantFiled: October 18, 2007Date of Patent: February 15, 2011Assignee: Nanosys, Inc.Inventors: Larry Bock, R. Hugh Daniels, Stephen Empedocles, John C. Owicki
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Publication number: 20100285972Abstract: This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates, as well as methods and uses for such substrates.Type: ApplicationFiled: October 17, 2007Publication date: November 11, 2010Applicant: Nanosys, Inc.Inventors: Roberto Dubrow, Robert Hugh Daniels, J. Wallace Parce, Matthew Murphy, Jim Hamilton, Erik Scher, Dave Stumbo, Chunming Niu, Linda T. Romano, Jay Goldman, Vijendra Sahi, Jeffery A. Whiteford
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Patent number: 7803574Abstract: This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, a method of administering a composition to a patient is disclosed which comprises providing a composition-eluting device, said composition-eluting device comprising at least a first surface and a plurality of nanostructures attached to the first surface, and introducing the composition-eluting device into the body of the patient.Type: GrantFiled: February 22, 2007Date of Patent: September 28, 2010Assignee: Nanosys, Inc.Inventors: Tejal Desai, R. Hugh Daniels, Vijendra Sahi
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Patent number: 7755038Abstract: The present invention generally discloses the use of a nanostructured non-silicon thin film (such as an alumina or aluminum thin film) on a supporting substrate which is subsequently coated with an active layer of a material such as silicon or tungsten. The base, underlying non-silicon material generates enhanced surface area while the active layer assists in incorporating and transferring energy to one or more analytes adsorbed on the active layer when irradiated with a laser during laser desorption of the analyte(s). The present invention provides substrate surfaces that can be produced by relatively straightforward and inexpensive manufacturing processes and which can be used for a variety of applications such as mass spectrometry, hydrophobic or hydrophilic coatings, medical device applications, electronics, catalysis, protection, data storage, optics, and sensors.Type: GrantFiled: May 15, 2008Date of Patent: July 13, 2010Assignee: Nanosys, Inc.Inventors: Chunming Niu, Robert Hugh Daniels, Robert S. Dubrow, Jay L. Goldman
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Publication number: 20100147172Abstract: A thickened aqueous cleaning solution for removing residual ink images from the surface of a blanket used in offset lithographic printing which has been subjected to printing using radiation-curable ink. The cleaning solution comprises an alkaline builder, a thickener, a co-solvent, a surfactant and water. A method for removing the residual ink images from the blanket comprises removing the blanket from the offset lithographic printing press, applying a layer of the thickened aqueous cleaning solution to the blanket, rubbing the surface of the blanket, for example with rags or a scouring pad, and removing the soiled cleaning solution.Type: ApplicationFiled: June 26, 2007Publication date: June 17, 2010Applicant: ENVIRO IMAGE SOLUTIONS INCInventors: Hugh Daniel McDonald, Hao Wang
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Patent number: 7651944Abstract: Methods of positioning and orienting nanostructures, and particularly nanowires, on surfaces for subsequent use or integration. The methods utilize mask based processes alone or in combination with flow based alignment of the nanostructures to provide oriented and positioned nanostructures on surfaces. Also provided are populations of positioned and/or oriented nanostructures, devices that include populations of positioned and/or oriented nanostructures, systems for positioning and/or orienting nanostructures, and related devices, systems and methods.Type: GrantFiled: August 5, 2008Date of Patent: January 26, 2010Assignee: Nanosys, Inc.Inventors: Xiangfeng Duan, R. Hugh Daniels, Chunming Niu, Vijendra Sahi, James M. Hamilton, Linda T. Romano
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Publication number: 20090275826Abstract: The present invention relates to treating of reflective surfaces to prevent fouling. The present invention also relates to reflective materials treated to prevent fouling, as well as methods of using such reflective materials.Type: ApplicationFiled: April 29, 2009Publication date: November 5, 2009Applicant: Nanosys, Inc.Inventors: Robert Enzerink, R. Hugh Daniels
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Patent number: 7579077Abstract: This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates, as well as methods and uses for such substrates.Type: GrantFiled: May 5, 2004Date of Patent: August 25, 2009Assignee: Nanosys, Inc.Inventors: Robert Dubrow, Robert Hugh Daniels
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Publication number: 20090192429Abstract: Methods, systems, and apparatuses for nanomaterial-enhanced hemostatic medical devices are provided. Hemostatic materials and structures are provided that induce coagulation of blood at a wound/opening caused by trauma, a surgical procedure, ulceration, or other cause. The hemostatic materials and structures may incorporate nanostructures and/or further hemostatic elements such as polymers and/or glass beads. The hemostatic materials and structures may be resorbable. Example embodiments include hemostatic bandages, hemostatic plugs, and hemostatic formulations.Type: ApplicationFiled: December 5, 2008Publication date: July 30, 2009Applicant: NANOSYS, INC.Inventors: R. Hugh Daniels, Robert S. Dubrow, Robert Enzerink, Esther Li, Vijendra Sahi, Jay L. Goldman, J. Wallace Parce
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Publication number: 20090176221Abstract: The use of semiconductor nanocrystals as detectable labels in various chemical and biological applications is disclosed. The methods find use for detecting a single analyte, as well as multiple analytes by using more than one semiconductor nanocrystal as a detectable label, each of which emits at a distinct wavelength.Type: ApplicationFiled: May 19, 2008Publication date: July 9, 2009Applicant: INVITROGEN CORPORATIONInventors: Marcel P. Bruchez, R. Hugh Daniels, Stephen A. Empedocles, Vince E. Phillips, Edith Y. Wong, Donald A. Zehnder
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Publication number: 20090124034Abstract: The present invention generally discloses the use of a nanostructured non-silicon thin film (such as an alumina or aluminum thin film) on a supporting substrate which is subsequently coated with an active layer of a material such as silicon or tungsten. The base, underlying non-silicon material generates enhanced surface area while the active layer assists in incorporating and transferring energy to one or more analytes adsorbed on the active layer when irradiated with a laser during laser desorption of the analyte(s). The present invention provides substrate surfaces that can be produced by relatively straightforward and inexpensive manufacturing processes and which can be used for a variety of applications such as mass spectrometry, hydrophobic or hydrophilic coatings, medical device applications, electronics, catalysis, protection, data storage, optics, and sensors.Type: ApplicationFiled: May 15, 2008Publication date: May 14, 2009Applicant: NANOSYS, INC.Inventors: Chunming Niu, R. Hugh Daniels, Robert S. Dubrow, Jay L. Goldman
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Publication number: 20080293244Abstract: Methods of positioning and orienting nanostructures, and particularly nanowires, on surfaces for subsequent use or integration. The methods utilize mask based processes alone or in combination with flow based alignment of the nanostructures to provide oriented and positioned nanostructures on surfaces. Also provided are populations of positioned and/or oriented nanostructures, devices that include populations of positioned and/or oriented nanostructures, systems for positioning and/or orienting nanostructures, and related devices, systems and methods.Type: ApplicationFiled: August 5, 2008Publication date: November 27, 2008Applicant: NANOSYS, INC.Inventors: Xiangfeng Duan, Hugh Daniels, Chunming Niu, Vijendra Sahi, James Hamilton, Linda T. Romano
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Patent number: 7422980Abstract: Methods of positioning and orienting nanostructures, and particularly nanowires, on surfaces for subsequent use or integration. The methods utilize mask based processes alone or in combination with flow based alignment of the nanostructures to provide oriented and positioned nanostructures on surfaces. Also provided are populations of positioned and/or oriented nanostructures, devices that include populations of positioned and/or oriented nanostructures, systems for positioning and/or orienting nanostructures, and related devices, systems and methods.Type: GrantFiled: November 21, 2006Date of Patent: September 9, 2008Assignee: Nanosys, Inc.Inventors: Xiangfeng Duan, R. Hugh Daniels, Chunming Niu, Vijendra Sahi, James M. Hamilton, Linda T. Romano
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Publication number: 20080200028Abstract: Methods of positioning and orienting nanostructures, and particularly nanowires, on surfaces for subsequent use or integration. The methods utilize mask based processes alone or in combination with flow based alignment of the nanostructures to provide oriented and positioned nanostructures on surfaces. Also provided are populations of positioned and/or oriented nanostructures, devices that include populations of positioned and/or oriented nanostructures, systems for positioning and/or orienting nanostructures, and related devices, systems and methods.Type: ApplicationFiled: November 21, 2006Publication date: August 21, 2008Applicant: Nanosys, Inc.Inventors: Xiangfeng Duan, Hugh Daniels, Chunming Niu, Vijendra Sahi, James Hamilton, Linda T. Romano
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Patent number: 7391018Abstract: The present invention generally discloses the use of a nanostructured non-silicon thin film (such as an alumina or aluminum thin film) on a supporting substrate which is subsequently coated with an active layer of a material such as silicon or tungsten. The base, underlying non-silicon material generates enhanced surface area while the active layer assists in incorporating and transferring energy to one or more analytes adsorbed on the active layer when irradiated with a laser during laser desorption of the analyte(s). The present invention provides substrate surfaces that can be produced by relatively straightforward and inexpensive manufacturing processes and which can be used for a variety of applications such as mass spectrometry, hydrophobic or hydrophilic coatings, medical device applications, electronics, catalysis, protection, data storage, optics, and sensors.Type: GrantFiled: September 14, 2005Date of Patent: June 24, 2008Assignee: Nanosys, Inc.Inventors: Chunming Niu, Robert Hugh Daniels, Robert S. Dubrow, Jay L. Goldman
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Publication number: 20080073505Abstract: The present invention generally discloses the use of a nanostructured non-silicon thin film (such as an alumina or aluminum thin film) on a supporting substrate which is subsequently coated with an active layer of a material such as silicon or tungsten. The base, underlying non-silicon material generates enhanced surface area while the active layer assists in incorporating and transferring energy to one or more analytes adsorbed on the active layer when irradiated with a laser during laser desorption of the analyte(s). The present invention provides substrate surfaces that can be produced by relatively straightforward and inexpensive manufacturing processes and which can be used for a variety of applications such as mass spectrometry, hydrophobic or hydrophilic coatings, medical device applications, electronics, catalysis, protection, data storage, optics, and sensors.Type: ApplicationFiled: September 14, 2005Publication date: March 27, 2008Applicant: Nanosys, Inc.Inventors: Chunming Niu, Robert Hugh Daniels, Robert S. Dubrow, Jay L. Goldman
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Patent number: 7303875Abstract: Methods of detecting components of interest, e.g., nucleic acids and sugars, are provided. The methods comprise contacting one or more nanowires comprising a functional group with a sample containing the component or components of interest. In one embodiment, the functional group comprises a hairpin oligonucleotide, e.g., a hairpin that changes conformation upon binding the component of interest, e.g., a nucleic acid. The change in conformation produces a change in charge that is detected. In another embodiment, the functional group comprises an enzyme, e.g., glucose oxidase, which produces a change in pH when glucose is present in a sample.Type: GrantFiled: October 9, 2003Date of Patent: December 4, 2007Assignee: Nanosys, Inc.Inventors: Larry Bock, R. Hugh Daniels, Stephen Empedocles
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Patent number: 7164209Abstract: Methods of positioning and orienting nanostructures, and particularly nanowires, on surfaces for subsequent use or integration. The methods utilize mask based processes alone or in combination with flow based alignment of the nanostructures to provide oriented and positioned nanostructures on surfaces. Also provided are populations of positioned and/or oriented nanostructures, devices that include populations of positioned and/or oriented nanostructures, systems for positioning and/or orienting nanostructures, and related devices, systems and methods.Type: GrantFiled: December 1, 2004Date of Patent: January 16, 2007Assignee: Nanosys, Inc.Inventors: Xiangfeng Duan, R. Hugh Daniels, Chunming Niu, Vijendra Sahi, James M. Hamilton, Linda T. Romano
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Patent number: 6872645Abstract: Methods of positioning and orienting nanostructures, and particularly nanowires, on surfaces for subsequent use or integration. The methods utilize mask based processes alone or in combination with flow based alignment of the nanostructures to provide oriented and positioned nanostructures on surfaces. Also provided are populations of positioned and/or oriented nanostructures, devices that include populations of positioned and/or oriented nanostructures, systems for positioning and/or orienting nanostructures, and related devices, systems and methods.Type: GrantFiled: September 10, 2002Date of Patent: March 29, 2005Assignee: Nanosys, Inc.Inventors: Xiangfeng Duan, Hugh Daniels, Chunming Niu, Vijendra Sahi, James Hamilton, Linda T. Romano