Abstract: Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide implicated in a wide range of functions, such as nociception and in primary headaches. PACAP is a member of the secretin/vasoactive intestinal peptide (VIP) Zgrowth hormone releasing hormone (GHRH) family. The present disclosure generally relates to anti-PACAP antibodies, pharmaceutical compositions comprising such antibodies, and methods of producing and using such antibodies.

Abstract: The present disclosure generally relates to anti-PACAP antibodies, pharmaceutical compositions comprising such antibodies, and methods of producing and using such antibodies.

Abstract: The present disclosure generally relates to anti-PACAP antibodies, pharmaceutical compositions comprising such antibodies, and methods of producing and using such antibodies.

Abstract: A system and method for producing hydrogen wherein the system comprises at least one electrolyzer adapted to be located within a subterranean formation, at least one electrical supply cable having a length selected to extend from the at least one electrolyzer to a ground surface power supply, at least one supply tubing string having a length selected to extend from the at least one electrolyzer to a water supply at the ground surface and at least one collection tubing string having a length selected to extend from the at least one electrolyzer to a collection location at the ground surface. The method comprises providing a well from a surface to an underground formation, locating at least one electrolyzer in the well, supplying the at least one electrolyzer with supply electricity, supplying the at least one electrolyzer with supply water, producing hydrogen gas at the electrolyzer and collecting and transporting the produced hydrogen gas to the surface.

Abstract: The present disclosure generally relates to anti-PACAP antibodies, pharmaceutical compositions comprising such antibodies, and methods of producing and using such antibodies.