Patents by Inventor Hugh N. Nellans

Hugh N. Nellans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4"-deoxyerythromycin derivatives
    Patent number: 5834438
    Abstract: 4"-Deoxy derivatives of erythromycin having the Formula (I) ##STR1## and pharmaceutically acceptable salts thereof, which are enhancers of gastric motility but have minimal antibacterial activity, as well as pharmaceutical compositions containing the same and methods for their use and preparation.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: November 10, 1998
    Assignee: Abbott Laboratories
    Inventors: Paul A. Lartey, Larry L. Klein, Ramin Faghih, Hugh N. Nellans
  • Process for preparing 4-deoxyerythromycin derivatives
    Patent number: 5654411
    Abstract: 4"-Deoxy derivatives of erythromycin having the Formula (I) ##STR1## and pharmaceutically acceptable salts thereof, which are enhancers of gastric motility but have minimal antibacterial activity, as well as pharmaceutical compositions containing the same and methods for their use and preparation.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: August 5, 1997
    Assignee: Abbott Laboratories
    Inventors: Paul A. Lartey, Larry L. Klein, Ramin Faghih, Hugh N. Nellans
  • 4"-deoxyerythromycin derivatives
    Patent number: 5578579
    Abstract: 4"-Deoxy derivatives of erythromycin having the Formula (I) ##STR1## and pharmaceutically acceptable salts thereof, which are enhancers of gastric motility but have minimal antibacterial activity, as well as pharmaceutical compositions containing the same and methods for their use and preparation.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: November 26, 1996
    Assignee: Abbott Laboratories
    Inventors: Paul A. Lartey, Larry L. Klein, Ramin Faghih, Hugh N. Nellans
  • Macrocyclic lactam prokinetic agents
    Patent number: 5554605
    Abstract: Macrocylic lactam compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof, wherein A is selected from ##STR2## also disclosed are synthetic processes and intermediates useful in the preparation of the compounds of the invention, as well as compositions containing the same and methods for their use in stimulating contractile motion of the gastrointestinal tract.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: September 10, 1996
    Assignee: Abbott Laboratories
    Inventors: Leslie A. Freiberg, Carla Edwards, Richard J. Pariza, Hugh N. Nellans
  • Macrocyclic lactam prokinetic agents
    Patent number: 5538961
    Abstract: Macrocylic lactam compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof, wherein A is selected from ##STR2## also disclosed are synthetic processes and intermediates useful in the preparation of the compounds of the invention, as well as compositions containing the same and methods for their use in stimulating contractile motion of the gastrointestinal tract.
    Type: Grant
    Filed: August 30, 1993
    Date of Patent: July 23, 1996
    Assignee: Abbott Laboratories
    Inventors: Leslie A. Freiberg, Carla Edwards, Richard J. Pariza, Hugh N. Nellans
  • Macrocyclic lactam prokinetic agents
    Patent number: 5523401
    Abstract: Macrocylic lactam compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof, wherein A is selected from ##STR2## also disclosed are synthetic processes and intermediates useful in the preparation of the compounds of the invention, as well as compositions containing the same and methods for their use in stimulating contractile motion of the gastrointestinal tract.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: June 4, 1996
    Assignee: Abbott Laboratories
    Inventors: Leslie A. Freiberg, Carla Edwards, Richard J. Pariza, Hugh N. Nellans
  • Macrocyclic lactam prokinetic agents
    Patent number: 5523418
    Abstract: Macrocylic lactam compounds of formula (i) ##STR1## and pharmaceutically acceptable salts thereof, wherein A is selected from ##STR2## also disclosed are synthetic processes and intermediates useful in the preparation of the compounds of the invention, as well as compositions containing the same and methods for their use in stimulating contractile motion of the gastrointestinal tract.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: June 4, 1996
    Assignee: Abbott Laboratories
    Inventors: Leslie A. Freiberg, Carla Edwards, Richard J. Pariza, Hugh N. Nellans
  • Derivatives of tetrapeptides as CCK agonists
    Patent number: 5270302
    Abstract: Selective and potent Type-A CCK receptor agonists of formula (I):X--Y--Z--Q (I)or a pharmaceutically acceptable salt thereof, wherein,X is selected from ##STR1## Y is selected from ##STR2## Z is ##STR3## and Q is ##STR4## or pharmaceutically-acceptable salts thereof, useful in the treatment of gastrointestinal disorders (including gallbladder disorders), central nervous system disorders, insulin-related disorders and pain, as well as in appetite regulation.
    Type: Grant
    Filed: June 17, 1991
    Date of Patent: December 14, 1993
    Assignee: Abbott Laboratories
    Inventors: Kazumi Shiosaki, Alex M. Nadzan, Hana Kopecka, Youe-Kong Shue, Mark W. Holladay, Chun W. Lin, Hugh N. Nellans