Patents by Inventor Hugh O. Pettit

Hugh O. Pettit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR REDUCING RESPIRATORY DEPRESSION AND ATTENDANT SIDE EFFECTS OF MU OPIOID COMPOUNDS
    Publication number: 20080193383
    Abstract: A method of reducing, treating or preventing drug-mediated respiratory depression, muscle rigidity, or nausea/vomiting in an animal, incident to the administration to said animal of a mixed delta/mu opioid agonist or a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a delta receptor agonist compound. Preferred examples of such delta receptor agonist compound include diarylmethyl piperazine compounds and diarylmethyl piperidine compounds, and pharmaceutical compositions thereof, having utility in medical therapy for reducing respiratory depression associated with certain analgesics, such as mu opiates.
    Type: Application
    Filed: April 7, 2008
    Publication date: August 14, 2008
    Inventors: Kwen-Jen Chang, Robert W. McNutt, Hugh O. Pettit, Michael J. Bishop
  • Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
    Patent number: 6919350
    Abstract: A method of reducing, treating or preventing drug-mediated respiratory depression, muscle rigidity, or nausea/vomiting in an animal, incident to the administration to said animal of a mixed delta/mu opioid agonist or a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a delta receptor agonist compound. Preferred examples of such delta receptor agonist compound include diarylmethyl piperazine compounds and diarylmethyl piperidine compounds, and pharmaceutical compositions thereof, having utility in medical therapy for reducing respiratory depression associated with certain analgesics, such as mu opiates.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: July 19, 2005
    Assignee: Ardent Pharmaceuticals, Inc.
    Inventors: Kwen-Jen Chang, Robert W. McNutt, Jr., Hugh O. Pettit, Michael J. Bishop
  • Compositions and Methods for Reducing Respiratory Depression and Attendant SIde Effects of Mu Opioid Compounds
    Publication number: 20020111359
    Abstract: A method of reducing, treating or preventing drug-mediated respiratory depression, muscle rigidity, or nausea/vomiting in an animal, incident to the administration to said animal of a mixed delta/mu opioid agonist or a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a delta receptor agonist compound. Preferred examples of such delta receptor agonist compound include diarylmethyl piperazine compounds and diarylmethyl piperidine compounds, and pharmaceutical compositions thereof, having utility in medical therapy for reducing respiratory depression associated with certain analgesics, such as mu opiates.
    Type: Application
    Filed: October 9, 2001
    Publication date: August 15, 2002
    Applicant: Ardent Pharmaceuticals, Inc.
    Inventors: Kwen-Jen Chang , Robert W. McNutt , Hugh O. Pettit , Michael J. Bishop
  • Methods for reducing respiratory depression and attendant side effects of mu opioid compounds
    Patent number: 6300332
    Abstract: A method of reducing, treating or preventing drug-mediated respiratory depression, muscle rigidity, or nausea/vomiting in an animal, incident to the administration to said animal of a mixed delta/mu opioid agonist or a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a delta receptor agonist compound.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: October 9, 2001
    Assignee: Delta Pharmaceuticals, Inc.
    Inventors: Kwen-Jen Chang, Robert W. McNutt, Jr., Hugh O. Pettit, Michael J. Bishop
  • Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
    Patent number: 5985880
    Abstract: A method of reducing, treating or preventing drug-mediated respiratory depression in an animal, incident to the administration to said animal of a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a .delta. receptor agonist compound.
    Type: Grant
    Filed: July 3, 1997
    Date of Patent: November 16, 1999
    Assignee: Delta Pharmaceuticals
    Inventors: Kwen-Jen Chang, Robert W. McNutt, Jr., Hugh O. Pettit, Michael J. Bishop
  • Compositions and methods for reducing respiratory depression
    Patent number: 5807858
    Abstract: The present invention relates to, inter alia, methods and compositions for reducing, treating or preventing respiratory depression in an animal, using a compound of the formula: ##STR1## wherein: Ar, G, Z, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are as defined in specification,or a pharmaceutically acceptable ester or salt thereof.
    Type: Grant
    Filed: June 5, 1996
    Date of Patent: September 15, 1998
    Assignee: Delta Pharmaceutical, Inc.
    Inventors: Kwen-Jen Chang, Robert W. McNutt, Jr., Hugh O. Pettit, Michael J. Bishop