Patents by Inventor Hugo BRASSELET

Hugo BRASSELET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHEMOENZYMATIC PROCESS FOR COPRODUCTION OF A DISULFIDE AND A SULFOXIDE OR A SULFONE
    Publication number: 20230159447
    Abstract: Chemoenzymatic process for coproducing a disulfide and a sulfoxide or a sulfone The present invention relates to a chemoenzymatic process for coproducing disulfide and sulfoxide or sulfone from a composition M comprising: 1) a sulfide, 2) optionally an oxidizing agent, 3) an organic compound bearing at least one thiol group, 4) an enzyme E catalyzing the oxidation of said sulfide to sulfoxide or to sulfone, 5) an enzyme D catalyzing the formation of a disulfide bridge between two equivalents of said organic compound bearing at least one thiol group to form a dimer, and 6) a cofactor common to the two enzymes E and D; and also to a composition enabling especially the implementation of this process. The present invention also relates to the use of a mercaptan for reducing a disulfide bridge formed between two equivalents of an organic compound bearing at least one thiol group, and more particularly to the use thereof as regeneration substrate of the process described above.
    Type: Application
    Filed: March 3, 2021
    Publication date: May 25, 2023
    Applicants: Arkema France, Centre National De La Recherche Scientifique - CNRS, Universite d'AIX-Marseille
    Inventors: Georges Fremy, Hugo Brasselet, Jean-Christophe Lec, Véronique Alphand, Katia Duquesne
  • SELECTIVE PROCESS FOR THE PREPARATION OF SULFONES BY ENZYMATIC CATALYSIS
    Publication number: 20230016226
    Abstract: The present invention relates to a selective process for preparing sulfones from sulfides by enzymatic catalysis, and to a composition comprising a symmetrical sulfide, an oxidoreductase enzyme catalyzing the oxidation of said symmetrical sulfide to symmetrical sulfone; optionally at least one cofactor C of said enzyme E; and an oxidant, which allows in particular the implementation of said process.
    Type: Application
    Filed: June 12, 2020
    Publication date: January 19, 2023
    Applicants: Arkema France, Centre National de la Recherche Scientifique (CNRS), Universite d'Aix-Marseille
    Inventors: Georges Fremy, Hugo Brasselet, Véronique Alphand, Katia Duquesne
  • SELECTIVE PROCESS FOR PREPARING SULFOXIDES BY ENZYMATIC CATALYSIS
    Publication number: 20220259624
    Abstract: The present invention relates to a selective process for preparing sulfoxides from sulfides by enzymatic catalysis, and to a composition comprising a symmetrical sulfide, an oxidoreductase enzyme catalyzing the oxidation of said symmetrical sulfide to symmetrical sulfoxide; optionally at least one cofactor C of said enzyme E; and an oxidant, which allows in particular the implementation of said process.
    Type: Application
    Filed: June 12, 2020
    Publication date: August 18, 2022
    Applicants: Arkema France, Centre National de la Recherche Scientifique (CNRS), Universite d'Aix-Marseille
    Inventors: Georges Fremy, Hugo Brasselet, Véronique Alphand, Katia Duquesne
  • Method for producing mercaptans by hydrogen-assisted disulfide enzyme hydrogenolysis
    Patent number: 10648007
    Abstract: Provided is an enzymatic process for the preparation of a mercaptan of formula R—SH from disulfides utilizing hydrogen.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: May 12, 2020
    Assignee: ARKEMA FRANCE
    Inventors: Georges Fremy, Arnaud Masselin, Hugo Brasselet
  • Method for producing L-methionine
    Patent number: 10563236
    Abstract: Provided is an enzymatic process for preparing L-methionine from diethyl disulfide.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: February 18, 2020
    Assignee: Akema France
    Inventors: Georges Fremy, Arnaud Masselin, Hugo Brasselet
  • METHOD FOR PRODUCING L-METHIONINE
    Publication number: 20180282772
    Abstract: Provided is an enzymatic process for preparing L-methionine from diethyl disulfide.
    Type: Application
    Filed: September 29, 2016
    Publication date: October 4, 2018
    Applicant: Arkema France
    Inventors: Georges FREMY, Arnaud MASSELIN, Hugo BRASSELET
  • METHOD FOR PRODUCING MERCAPTANS BY HYDROGEN-ASSISTED DISULFIDE ENZYME HYDROGENOLYSIS
    Publication number: 20180273991
    Abstract: Provided is an enzymatic process for the preparation of a mercaptan of formula R—SH from disulfides utilizing hydrogen.
    Type: Application
    Filed: September 29, 2016
    Publication date: September 27, 2018
    Applicant: Arkema France
    Inventors: Georges FREMY, Arnaud MASSELIN, Hugo BRASSELET