Patents by Inventor Hugo Garrido-Hernandez

Hugo Garrido-Hernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7173020
    Abstract: Novel phosphoramidate derivatives of hydroxy functional or amino functional compounds, including amino acids, peptides, peptidomimetics and nucleotide analogs, are described. The compounds enable enhanced intracellular delivery of drugs as their corresponding phosphate esters or amides. Described phosphoramidate compounds exhibit antiproliferative activity. Pharmaceutical formulations are provided for treatment of cancers.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: February 6, 2007
    Assignee: Purdue Research Foundation
    Inventors: Richard F. Borch, Hugo Garrido-Hernandez, Sandra C. Tobias
  • Publication number: 20050171060
    Abstract: Novel phosphoramidate derivatives of hydroxy functional or amino functional compounds, including amino acids, peptides, peptidomimetics and nucleotide analogs, are described. The compounds enable enhanced intracellular delivery of drugs as their corresponding phosphate esters or amides. Described phosphoramidate compounds exhibit antiproliferative activity. Pharmaceutical formulations are provided for treatment of cancers.
    Type: Application
    Filed: February 8, 2005
    Publication date: August 4, 2005
    Inventors: Richard Borch, Hugo Garrido-Hernandez, Sandra Tobias
  • Patent number: 6903081
    Abstract: Novel phosphoramidate derivatives of hydroxy functional or amino functional compounds, including amino acids, peptides, peptidomimetics and nucleotide analogs, are described. The compounds enable enhanced intracellular delivery of drugs as their corresponding phosphate esters or amides. Described phosphoramidate compounds exhibit antiproliferative activity. Pharmaceutical formulations are provided for treatment of cancers.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: June 7, 2005
    Assignee: Purdue Research Foundation
    Inventors: Richard F. Borch, Hugo Garrido-Hernandez, Sandra C. Tobias
  • Publication number: 20020004594
    Abstract: Novel phosphoramidate derivatives of hydroxy functional or amino functional compounds, including amino acids, peptides, peptidomimetics and nucleotide analogs, are described. The compounds enable enhanced intracellular delivery of drugs as their corresponding phosphate esters or amides. Described phosphoramidate compounds exhibit antiproliferative activity. Pharmaceutical formulations are provided for treatment of cancers.
    Type: Application
    Filed: March 30, 2001
    Publication date: January 10, 2002
    Inventors: Richard F. Borch, Hugo Garrido-Hernandez, Sandra C. Tobias