Patents by Inventor Hugo Gonzalez

Hugo Gonzalez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200346366
    Abstract: Methods and apparatus are provided for pressure casting ceramic bodies. Methods and apparatus are provided for rapid ejection of cast ceramic bodies from a mold. A mold is described that has an impermeable cavity surface to provide dry release of the cast body.
    Type: Application
    Filed: April 30, 2020
    Publication date: November 5, 2020
    Inventors: Hugo Gonzalez, Sreeram Balasubramanian, Mathew David Campbell
  • Patent number: 7238522
    Abstract: An apparatus and a method for isolating a biologic product, such as plasmid DNA, from cells. The method involves lysing cells in a controlled manner separate insoluble components from a fluid lysate containing cellular components of interest, followed by membrane chromatographic techniques to purify the cellular components of interest. The process utilizes a unique lysis apparatus, ion exchange and, optionally, hydrophobic interaction chromatography membranes in cartridge form, and ultrafiltration. The process can be applied to any biologic product extracted from a cellular source. The process uses a lysis apparatus, including a high shear, low residence-time mixer for advantageously mixing a cell suspension with a lysis solution, a hold time that denatures impurities, and an air-sparging bubble mixer that gently yet thoroughly mixes lysed cells with a neutralization/precipitation buffer and floats compacted precipitated cellular material.
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: July 3, 2007
    Assignee: ADViSYS, Inc.
    Inventors: Henry Hebel, Sriram Ramakrishnan, Hugo Gonzalez, Jeff Darnell
  • Publication number: 20060200076
    Abstract: The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. A device includes a flow control member for placement in an air passageway communicating with a lung portion, and when deployed in the air passageway inhibits a therapeutic agent distal of the control member from moving proximal of the control member, and includes the therapeutic agent associated with the flow control member. The control member may inhibit movement of the therapeutic agent by limiting airflow, and may include a one-way valve limiting exhalation of air from the lung portion. The control member may include a flexible membrane impervious to air flow, or a separator arranged to inhibit the movement of the therapeutic agent. The control member may include at least one anchor, and the anchor may be releasable from the air passageway for removal of the intra-bronchial device.
    Type: Application
    Filed: May 3, 2006
    Publication date: September 7, 2006
    Inventors: Hugo Gonzalez, Steven Springmeyer, Richard Shea, John Wang, Lauri DeVore
  • Publication number: 20060074382
    Abstract: The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. A device includes a flow control member for placement in an air passageway communicating with a lung portion, and when deployed in the air passageway inhibits a therapeutic agent distal of the control member from moving proximal of the control member, and includes the therapeutic agent associated with the flow control member. The control member may inhibit movement of the therapeutic agent by limiting airflow, and may include a one-way valve limiting exhalation of air from the lung portion. The control member may include a flexible membrane impervious to air flow, or a separator arranged to inhibit the movement of the therapeutic agent. The control member may include at least one anchor, and the anchor may be releasable from the air passageway for removal of the intra-bronchial device.
    Type: Application
    Filed: August 15, 2005
    Publication date: April 6, 2006
    Inventors: Hugo Gonzalez, Steven Springmeyer, Richard Shea, John Wang, Lauri DeVore
  • Publication number: 20050137714
    Abstract: Methods and systems for minimally invasively treating an air leak in a lung comprise the steps of detecting an air leak in a lung; locating an airway in fluid communication with the air leak, introducing a bronchoscope into a patient's airway to a position adjacent the target section and occluding an airway upstream of the air leak for a period of time. The airway occlusion is preferably removed after the air leak has substantially permanently healed. The method can also include the injection of a substance into the airway on a distal side of the occlusion.
    Type: Application
    Filed: December 22, 2003
    Publication date: June 23, 2005
    Inventors: Hugo Gonzalez, Steven Springmeyer, William Sirokman
  • Publication number: 20050131276
    Abstract: A constriction device that constricts body tissue is viewable under X ray fluoroscopy. The device includes an elongated sleeve. The sleeve includes opposed opened ends and is formed from expandable or elastic material to receive therein, when in an expanded condition, body tissue to be constricted and to constrict the body tissue therein when released from the expanded condition. At least a portion of the sleeve includes X ray opaque material rendering the device visible under X ray fluoroscopy.
    Type: Application
    Filed: February 1, 2005
    Publication date: June 16, 2005
    Inventors: Clifton Alferness, Robert Barry, Clint Finger, Hugo Gonzalez
  • Publication number: 20050043745
    Abstract: A resection device and method permits safe and efficient encapsulation, isolation and resection of body tissue. The device includes a sheath of flexible and severable material configured to receive the body tissue to be resectioned as it is drawn therein. The sheath may be expandable and held in an expanded condition as the body tissue to be resectioned is drawn into the sheath. Thereafter, the sheath is permitted to collapse about the body tissue to contain and constrict the body tissue. Once the body tissue to be resectioned is disposed in the sheath, the sheath is severed to resection the body tissue.
    Type: Application
    Filed: September 13, 2004
    Publication date: February 24, 2005
    Inventors: Clifton Alferness, Hugo Gonzalez
  • Publication number: 20050033344
    Abstract: An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.
    Type: Application
    Filed: September 3, 2004
    Publication date: February 10, 2005
    Inventors: David Dillard, Hugo Gonzalez, Seung Yi, Lauri DeVore, Mia Park, Dean Corcoran, Jenni Rimbaugh, Clifton Alferness
  • Publication number: 20050014245
    Abstract: An apparatus and a method for isolating a biologic product, such as plasmid DNA, from cells. The method involves lysing cells in a controlled manner separate insoluble components from a fluid lysate containing cellular components of interest, followed by membrane chromatographic techniques to purify the cellular components of interest. The process utilizes a unique lysis apparatus, ion exchange and, optionally, hydrophobic interaction chromatography membranes in cartridge form, and ultrafiltration. The process can be applied to any biologic product extracted from a cellular source. The process uses a lysis apparatus, including a high shear, low residence-time mixer for advantageously mixing a cell suspension with a lysis solution, a hold time that denatures impurities, and an air-sparging bubble mixer that gently yet thoroughly mixes lysed cells with a neutralization/precipitation buffer and floats compacted precipitated cellular material.
    Type: Application
    Filed: May 27, 2004
    Publication date: January 20, 2005
    Applicant: ADVISYS, Inc.
    Inventors: Henry Hebel, Sriram Ramakrishnan, Hugo Gonzalez, Jeff Darnell
  • Patent number: 6374422
    Abstract: A head guard for soccer players for protecting the forehead of a soccer player when the forehead is struck with a soccer ball. The head guard for soccer players includes a plate having a outer surface and an inner surface. The plate has a bottom edge, a pair of side edges and a top edge. The inner surface is concave and the outer surface is convex. The bottom edge generally lies in a plane such that the plate generally arcs back from the bottom edge to the top edge. A head band is elongated and has a pair of ends. Each of the ends of the head band is attached to the plate and defines a loop for extending around a head such that the plate may be abutted against the forehead of the wearer. Each of the ends of the head band is positioned adjacent to the bottom edge and one of the side edges.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: April 23, 2002
    Inventors: Hugo Gonzalez, Maria Gonzalez, Oscar Gonzalez