Patents by Inventor Hugo Menzella

Hugo Menzella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified phospholipase C protein and method of processing vegetable oil
    Patent number: 10294463
    Abstract: A modified Bacillus cereus phospholipase C enzyme is provided, as well as a method of using the modified phospholipase C enzyme in a method of treating vegetable oil. In certain embodiments, this method may comprise combining a vegetable oil with an modified phospholipase C enzyme comprising an amino acid sequence that is at least 85% identical to the amino acid sequence of SEQ ID NO:1, wherein the amino acid residue at position 66 is a Trp (W) or Tyr (Y), and maintaining the combination under conditions suitable for the modified phospholipase C enzyme to catalyze the hydrolysis of phospholipids in the oil to produce diacylglycerol and a water soluble phosphate.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: May 21, 2019
    Inventors: Maria Eugenia Castelli, Hugo Menzella, Salvador Peiru, Leandro Vetcher
  • Enzymatic removal of steryl glycosides
    Patent number: 10287521
    Abstract: The present invention provides compositions and methods related to the production and use of enzymes suitable for reducing the amount of steryl glycosides or saturated monoacyl glycerols in a lipid mixture.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: May 14, 2019
    Inventors: Hugo Menzella, Salvador Peiru, Leandro Vetcher
  • ENZYMATIC REMOVAL OF STERYL GLYCOSIDES
    Publication number: 20170327756
    Abstract: The present invention provides compositions and methods related to the production and use of enzymes suitable for reducing the amount of steryl glycosides or saturated monoacyl glycerols in a lipid mixture.
    Type: Application
    Filed: May 15, 2017
    Publication date: November 16, 2017
    Applicant: KECLON S.A.
    Inventors: Hugo Menzella, Salvador Peiru, Leandro Vetcher, Hugo Menzella, Salvador Peiru, Leandro Vetcher
  • Modified Bacillus Cereus Phospholipase C Protein And Method Of Processing Vegetable Oil
    Publication number: 20170015981
    Abstract: A modified Bacillus cereus phospholipase C enzyme is provided, as well as a method of using the modified phospholipase C enzyme in a method of treating vegetable oil. In certain embodiments, this method may comprise combining a vegetable oil with an modified phospholipase C enzyme comprising an amino acid sequence that is at least 85% identical to the amino acid sequence of SEQ ID NO:1, wherein the amino acid residue at position 66 is a Trp (W) or Tyr (Y), and maintaining the combination under conditions suitable for the modified phospholipase C enzyme to catalyze the hydrolysis of phospholipids in the oil to produce diacylglycerol and a water soluble phosphate.
    Type: Application
    Filed: June 19, 2014
    Publication date: January 19, 2017
    Applicant: Keclon SA
    Inventors: Maria Eugenia Castelli, Hugo Menzella, Salvador Peiru, Leandro Vetcher
  • ENZYMATIC REMOVAL OF STERYL GLYCOSIDES
    Publication number: 20150141680
    Abstract: The present invention provides compositions and methods related to the production and use of enzymes suitable for reducing the amount of steryl glycosides or saturated monoacyl glycerols in a lipid mixture.
    Type: Application
    Filed: March 14, 2013
    Publication date: May 21, 2015
    Applicant: KECLON S.A.
    Inventors: Hugo Menzella, Salvador Peiru, Leandro Vetcher
  • Methods of making epothilones
    Patent number: 7955824
    Abstract: The invention provides novel compounds that may be used as intermediates in the preparation of epothilones, epothilone analogs and derivative, as well as new synthetic methods for producing the intermediates and products.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: June 7, 2011
    Assignee: Kosan Biosciences Incorporated
    Inventors: John R. Carney, Yong Li, Hugo Menzella, Ralph C. Reid
  • Macrolactams by engineered biosynthesis
    Patent number: 7855192
    Abstract: Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the biosynthesis of the natural starter unit 3-amino-5-hydroxybenzoic acid has been deleted.
    Type: Grant
    Filed: January 23, 2008
    Date of Patent: December 21, 2010
    Assignee: Kosan Biosciences, Inc.
    Inventors: Gary W. Ashley, Hugo Menzella, Janice Lau Wee, John R. Carney
  • Methods of Making Epothilones
    Publication number: 20090076289
    Abstract: The invention provides novel compounds that may be used as intermediates in the preparation of epothilones, epothilone analogs and derivative, as well as new synthetic methods for producing the intermediates and products.
    Type: Application
    Filed: May 9, 2008
    Publication date: March 19, 2009
    Applicant: Kosan Biosciences Incorporated
    Inventors: John R. Carney, Yong Li, Hugo Menzella, Ralph C. Reid
  • Macrolactams by engineered biosynthesis
    Publication number: 20080188450
    Abstract: Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the biosynthesis of the natural starter unit 3-amino-5-hydroxybenzoic acid has been deleted.
    Type: Application
    Filed: January 23, 2008
    Publication date: August 7, 2008
    Inventors: Gary W. Ashley, Hugo Menzella, Janice Lau Wee, John R. Carney