Abstract: An orthopaedic implant is provided for the treatment of avascular necrosis of the bone. The orthopaedic implant includes a hollow support structure and a synthetic vascular graft. The support structure defines a passageway and includes a proximal opening and a distal opening. The synthetic vascular graft is received, at least in part, within the passageway such that a proximal end portion of the synthetic vascular graft is received through the proximal opening of the support structure and a distal end portion of the synthetic vascular graft is received through the distal opening of the support structure.

Abstract: Active immunization and a formulation for treating or preventing osteolysis caused by Wear Particles, comprising: a) a Th2 -inducing adjuvant, and b) Wear Particles.

Abstract: The present invention provides a method for preparing a biomaterial involving extracting Collagen Type I (Col I) protein from small intestine submucosa (SIS) under conditions that preserve the native helical configuration. The extract of the present method contains a substantial amount of the alpha helical form of Col I. Further the present method includes inducing the Col I protein to form a polymer material in solution or on a target surface.

Abstract: The present invention provides a protein polymer material and a method for preparing the protein polymer material involving applying an energy such as electrical energy or gravitational energy to a protein to cause the protein to assemble in a controlled arrangement. The protein used in this method may be any suitable fibrillar protein capable of self-assembling.

Abstract: Irradiating osteolytic regions with UVB light.