Patents by Inventor Hugo Van Heuverswyn

Hugo Van Heuverswyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8101351
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position ?291 to nucleotide at position ?66 of the 5? untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV isolate to be iden
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: January 24, 2012
    Assignee: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20100120121
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position ?291 to nucleotide at position ?66 of the 5? untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV isolate to be iden
    Type: Application
    Filed: July 12, 2007
    Publication date: May 13, 2010
    Applicant: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 7390623
    Abstract: The present invention relates to 16S-23S rRNA spacer sequences from Staphylococcus aureus and their use in a method for detection and/or identification of Staphylococcus aureus . The invention further relates to a method for detection and identification of Staphylococcus aureus in a sample, involving the steps of: (i) optionally releasing, isolating and/or concentrating the polynucleic acids present in the sample; (ii) optionally amplifying the 16S-23S rRNA spacer region, or a part thereof, with at least one primer pair; (iii) detecting the presence of a 16S-23S rRNA spacer sequence; and (iv) identifying the Staphylococcus aureus present in the sample from the nucleic acid(s) detected in the sample.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: June 24, 2008
    Assignee: Innogenetics N.V.
    Inventors: Geert Jannes, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 7258982
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position ?291 to nucleotide at position ?66 of the 5? untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV isolate to be iden
    Type: Grant
    Filed: April 13, 2004
    Date of Patent: August 21, 2007
    Assignee: Innogenetics, S.A.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 7258977
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position -291 to nucleotide at position -66 of the 5? untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV isolate to be iden
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: August 21, 2007
    Assignee: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20050142575
    Abstract: The present invention relates to 16S-23S rRNA spacer sequences from Staphylococcus aureus and their use in a method for detection and/or identification of Staphylococcus aureus. The invention further relates to a method for detection and identification of Staphylococcus aureus in a sample, involving the steps of: (i) optionally releasing, isolating and/or concentrating the polynucleic acids present in the sample; (ii) optionally amplifying the 16S-23S rRNA spacer region, or a part thereof, with at least one primer pair; (iii) detecting the presence of a 16S-23S rRNA spacer sequence; and (iv) identifying the Staphylococcus aureus present in the sample from the nucleic acid(s) detected in the sample.
    Type: Application
    Filed: July 21, 2004
    Publication date: June 30, 2005
    Applicant: INNOGENETICS N.V.
    Inventors: Geert Jannes, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 6891026
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position ?291 to nucleotide at position ?66 of the 5? untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV isolate to be iden
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: May 10, 2005
    Assignee: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 6887985
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position ?291 to nucleotide at position ?66 of the 5? untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV isolate to be iden
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: May 3, 2005
    Assignee: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 6811978
    Abstract: The present invention relates to 16S-23S rRNA spacer sequences from Pseudomonas species and their use in a method for detection and/or identification of Pseudomonas species. The invention further it relates to a method for detection and identification of at least one Pseudomonas species, or for the simultaneous detection of several Pseudomonas species in a sample, involving the steps of: (i) optionally releasing, isolating and/or concentrating the polynucleic acids present in the sample; (ii) optionally amplifying the 16S-23S rRNA spacer region, or a part thereof, with at least one primer pair; (iii) detecting the presence of a 16S-23S rRNA spacer sequence; and (iv) identifying the Pseudomonas species present in the sample from the nucleic acid(s) detected in the sample.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: November 2, 2004
    Assignee: Innogenetics N.V.
    Inventors: Geert Jannes, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20040191768
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of:
    Type: Application
    Filed: April 13, 2004
    Publication date: September 30, 2004
    Applicant: INNOGENETICS, S.A.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20040053320
    Abstract: The invention relates to a probe consisting of at least about 15 nucleotides from the spacer region between rRNA genes of a non-viral organism, particularly prokaryotic organism and more particularly bacteria, and preferably from about 15 nucleotides to about the maximum number of nucleotides of the spacer region and more preferably from about 15 to about 100 nucleotides to be used for the detection of non-viral microorganisms.
    Type: Application
    Filed: September 25, 2003
    Publication date: March 18, 2004
    Applicant: N.V. Innogenetics S.A.
    Inventors: Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 6656689
    Abstract: The invention relates to a probe consisting of at least about 15 nucleotides from the spacer region between rRNA genes of a non-viral organism, particularly prokaryotic organism and more particularly bacteria, and preferably from about 15 nucleotides to about the maximum number of nucleotides of the spacer region and more preferably from about 15 to about 100 nucleotides to be used for the detection of non-viral microorganisms.
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: December 2, 2003
    Assignee: N.V. Innogenetics S.A.
    Inventors: Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20030215802
    Abstract: The present invention relates to a method for detection and identification of at least one microorganism, or for the simultaneous detection of several microorganisms in a sample.
    Type: Application
    Filed: August 17, 2001
    Publication date: November 20, 2003
    Applicant: Innogenetics N.V.
    Inventors: Geert Jannes, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 6548244
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position −291 to nucleotide at position −66 of the 5′ untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV i
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: April 15, 2003
    Assignee: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20030039954
    Abstract: Described is a new variety of retrovirus designated HIV-3, also known as HIV-1 subtype O, samples of which are deposited in the European Collection of Animal Cell Cultures (ECACC) under V88060301. Further described is a process to detect the HIV-3 retrovirus in biological liquids or tissue. One such process involves contacting a biological sample suspected of containing HIV-3 nucleic acids with a DNA probe corresponding to a segment of genomic HIV-3 retrovirus RNA, such as the LTR region, and detecting the hybridization products thereof.
    Type: Application
    Filed: May 9, 2001
    Publication date: February 27, 2003
    Applicant: Innogenetics N.V.
    Inventors: Robert De Leys, Bart Vanderborght, Eric Saman, Hugo Van Heuverswyn
  • Publication number: 20030036053
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of:
    Type: Application
    Filed: July 6, 2001
    Publication date: February 20, 2003
    Applicant: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 6495670
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position −291 to nucleotide at position −66 of the 5′ untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV i
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: December 17, 2002
    Assignee: Innogenetics, N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20020168626
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of:
    Type: Application
    Filed: July 6, 2001
    Publication date: November 14, 2002
    Applicant: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20020106638
    Abstract: The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of:
    Type: Application
    Filed: July 6, 2001
    Publication date: August 8, 2002
    Applicant: Innogenetics N.V.
    Inventors: Geert Maertens, Lieven Stuyver, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20020069422
    Abstract: The invention relates:
    Type: Application
    Filed: April 19, 1999
    Publication date: June 6, 2002
    Inventors: LUCIA FRANSEN, KATHLEEN DEVOS, ANDRE VAN DE VOORDE, HUGO VAN HEUVERSWYN