Patents by Inventor Hugues Mathis

Hugues Mathis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insertion of Multicopies of a Gene of Interest into the Genome of a Fungus
    Publication number: 20240384290
    Abstract: The invention relates to a method for inserting several copies of a gene of interest into the genome of a fungus, said method comprising a step of transforming said fungus by using a vector comprising an expression cassette, said cassette comprising: (1) a TEF1 promoter identical to the endogenous TEF1 promoter of the species of fungus, (2) a gene of interest, and (3) a terminator that is not the endogenous TEF1 terminator of the fungus species. The invention also relates to the fungi obtained by such a method, and to the various uses of the strains modified in this manner. (no figure).
    Type: Application
    Filed: April 29, 2022
    Publication date: November 21, 2024
    Applicant: IFP ENERGIES NOUVELLES
    Inventors: Hugues Mathis, Frédérique Bidard-Michelot
  • Variants of exoglucanases having improved activity and uses thereof
    Patent number: 10738291
    Abstract: The present invention relates to the expression and optimisation of enzymes involved in the breakdown of lignocellulosic biomass. The present invention relates to variants of the exoglucanase 2 of Trichoderma reesei, as well as to the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: August 11, 2020
    Assignees: IFP Energies nouvelles, Proteus, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS
    Inventors: Cecile Persillon, Christophe Ullmann, Celine Ayrinhac, Olivier Bonzom, Antoine Margeot, Hugues Mathis, Sebastien Fort, Sylvie Armand, Stephanie Pradeau
  • VARIANTS OF EXOGLUCANASES HAVING IMPROVED ACTIVITY AND USES THEREOF
    Publication number: 20170152498
    Abstract: The present invention relates to the expression and optimisation of enzymes involved in the breakdown of lignocellulosic biomass. The present invention specially relates to variants of the exoglucanase 2 of Trichoderma reesei, as well as to the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.
    Type: Application
    Filed: June 12, 2015
    Publication date: June 1, 2017
    Inventors: Cecile PERSILLON, Christophe ULLMANN, Celine AYRINHAC, Olivier BONZOM, Antoine MARGEOT, Hugues MATHIS, Sebastien FORT, Sylvie ARMAND, Stephanie PRADEAU
  • Polypetide with enhanced beta-glucosidase activity at low temperature
    Patent number: 9382555
    Abstract: The invention relates to a polypeptide which has enhanced beta-glucosidase activity at a temperature of between about 30° C. and about 35° C.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: July 5, 2016
    Assignees: IFP ENERGIES NOUVELLES, PROTÉUS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS
    Inventors: Antoine Margeot, Hugues Mathis, Celine Ayrinhac, Christophe Ullmann, Cecile Persillon, Sebastien Fort, Sylvie Armand, Maud Petit
  • Beta-glucosidase variants having improved activity, and uses thereof
    Patent number: 9309538
    Abstract: The present invention relates to the expression and optimization of enzymes involved in lignocellulosic biomass decomposition. The present invention relates more particularly to beta-glucosidase variants comprising at least one modification among the amino acids located at positions 225, 238, 240 and 241, according to the numbering in SEQ ID No. 2 of Trichoderma reesei beta-glucosidase, and also relates to the use of said variants having improved effectiveness in methods for cellulose decomposition and biofuel production.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: April 12, 2016
    Assignees: IFP Energies Nouvelles, PROTEUS
    Inventors: Nicolas Lopes-Ferreira, Antoine Margeot, Hugues Mathis, Laurent Fourage
  • Polypetide with Reinforced Beta-Glucosidase Activity at Low Temperature
    Publication number: 20150218593
    Abstract: The invention relates to a polypeptide which has enhanced beta-glucosidase activity at a temperature of between about 30° C. and about 35° C.
    Type: Application
    Filed: September 4, 2013
    Publication date: August 6, 2015
    Inventors: Antoine Margeot, Hugues Mathis, Céline Ayrinhac, Christophe Ullmann, Cécile Persillon, Sébastien Fort, Sylvie Armand, Maud Petit
  • Beta-Glucosidase Variants Having Improved Activity, and Uses Thereof
    Publication number: 20110171674
    Abstract: The present invention relates to the expression and optimization of enzymes involved in lignocellulosic biomass decomposition. The present invention relates more particularly to beta-glucosidase variants comprising at least one modification among the amino acids located at positions 225, 238, 240 and 241, according to the numbering in SEQ ID No. 2 of Trichoderma reesei beta-glucosidase, and also relates to the use of said variants having improved effectiveness in methods for cellulose decomposition and biofuel production.
    Type: Application
    Filed: September 10, 2009
    Publication date: July 14, 2011
    Applicant: IFP Energies Nouvelles
    Inventors: Nicolas Lopes-Ferreira, Antoine Margeot, Hugues Mathis, Laurent Fourage