Patents by Inventor Hui Cai

Hui Cai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ring Detacher
    Publication number: 20090100868
    Abstract: The present invention provides a ring detacher typically including typically including a base, a retainer, a screw and a handle bar, in which said retainer having a through-hole is located to standing on the base for passing through the finger wearing on the ring, said retainer also has a radial threaded hole crossing the frame of the retainer connecting to the through-hole rightly so that the screw can be secured in or out the through-hole via the threaded hole with the external thread engaging with the threaded hole, meanwhile the screw has a crowned pressing head built on the bottom end stretched into the inside of the through-hole, and said handle bar can be located on the top end of the screw. The present invention has the simplified structure, so the operation is very convenient, safety avoiding the embarrassment situation of being unable to pull the ring off happening.
    Type: Application
    Filed: October 17, 2007
    Publication date: April 23, 2009
    Inventor: Rong Hui Cai
  • Substituted pyrazoles
    Publication number: 20080300255
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: July 24, 2008
    Publication date: December 4, 2008
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20080293732
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: July 24, 2008
    Publication date: November 27, 2008
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7452890
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: November 18, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • BICYCLIC AMINOPROPYL TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
    Publication number: 20080269241
    Abstract: Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
    Type: Application
    Filed: February 14, 2008
    Publication date: October 30, 2008
    Inventors: Darin Allen, Michael K. Ameriks, Frank U. Axe, Matthew Burdett, Hui Cai, Ingrid Choong, James P. Edwards, Willard Lew, Steven P. Meduna
  • Substituted pyrazoles
    Patent number: 7429591
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: September 30, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7417046
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: August 26, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
    Publication number: 20080200454
    Abstract: Carbon-linked tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
    Type: Application
    Filed: February 14, 2008
    Publication date: August 21, 2008
    Inventors: Michael K. Ameriks, Frank U. Axe, James P. Edwards, Cheryl A. Grice, Hui Cai, Elizabeth Ann Gleason, Steven P. Meduna, Kevin L. Tays, John J. M. Wiener, Alvah T. Wickboldt
  • 2-Aminopyrimidine modulators of the histamine H4 receptor
    Publication number: 20080194577
    Abstract: 2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Application
    Filed: February 14, 2008
    Publication date: August 14, 2008
    Inventors: Hui Cai, Frank Chavez, James P. Edwards, Anne E. Fitzgerald, Jing Liu, Neelakandha S. Mani, Danielle K. Neff, Michele C. Rizzolio, Brad M. Savall, Deborah M. Smith, Jennifer D. Venable, Jianmei Wei, Ronald L. Wolin
  • Substituted pyrazoles
    Patent number: 7393850
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: July 1, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7388011
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: June 17, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Method for treating allergies using substituted pyrazoles
    Patent number: 7332494
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: February 19, 2008
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Yin Gu, Darin J. Gustin, Lars Karlsson, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Siquan Sun, Kevin L. Tays, Robin L. Thurmond, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7309703
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: December 18, 2007
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7265102
    Abstract: Substituted pyrazoles of general formula methods of manufacturing them, compositions containing them, and methods of using them to, for example, treat autoimmune diseases mediated by cathepsin S, and inhibit cathepsin S activity, are described.
    Type: Grant
    Filed: June 8, 2005
    Date of Patent: September 4, 2007
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Hui Cai, James P. Edwards, Steven P Meduna, Barbara A. Pio, Jianmei Wei
  • Heterocyclic Compounds
    Publication number: 20070185120
    Abstract: Certain thienopyrrolyl and furanopyrrolyl compounds are disclosed as useful to treat or prevent disorders and conditions mediated by the histamine H4 receptor, including allergic rhinitis.
    Type: Application
    Filed: April 13, 2007
    Publication date: August 9, 2007
    Inventors: Hui Cai, Nicholas Carruthers, Curt Dvorak, James Edwards, Annette Kwok, Jianmei Wei
  • Heterocyclic Compounds
    Publication number: 20070185131
    Abstract: Certain thienopyrrolyl and furanopyrrolyl compounds are disclosed as useful to treat or prevent disorders and conditions mediated by the histamine H4 receptor, including allergic rhinitis.
    Type: Application
    Filed: April 13, 2007
    Publication date: August 9, 2007
    Inventors: Hui Cai, Nicholas Carruthers, Curt Dvorak, James Edwards, Annette Kwok, Jianmei Wei
  • Heterocyclic compounds
    Patent number: 7226938
    Abstract: Certain thienopyrrolyl and furanopyrrolyl compounds are disclosed as useful to treat or prevent disorders and conditions mediated by the histamine H4 receptor, including allergic rhinitis.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: June 5, 2007
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Hui Cai, Nicholas I. Carruthers, Curt A. Dvorak, James P. Edwards, Annette K. Kwok, Jianmei Wei
  • Substituted pyrazoles and methods of treatment with substituted pyrazoles
    Publication number: 20070117785
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases or allergic conditions, including atopic allergic conditions, mediated by cathepsin S are described.
    Type: Application
    Filed: October 4, 2006
    Publication date: May 24, 2007
    Inventors: Christopher Butler, Hui Cai, James Edwards, Cheryl Grice, Darin Gustin, Lars Karlsson, Haripada Khatuya, Steven Meduna, Barbara Pio, Joanne Quan, Clark Sehon, Siquan Sun, Kevin Tays, Robin Thurmond, Jianmei Wei, Ann Welton
  • Method for treating allergies using substituted pyrazoles
    Publication number: 20070105841
    Abstract: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
    Type: Application
    Filed: October 31, 2006
    Publication date: May 10, 2007
    Inventors: J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Yin Gu, Darin Gustin, Lars Karlsson, Haripada Khatuya, Steven Meduna, Barbara Pio, Siquan Sun, Kevin Tays, Robin Thurmond, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20070021437
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 25, 2007
    Inventors: Mary Beavers, J. Breitenbucher, Hui Cai, James Edwards, Cheryl Grice, Darin Gustin, Haripada Khatuya, Steven Meduna, Barbara Pio, Kevin Tays, Jianmei Wei