Patents by Inventor Hui-Chen Lu

Hui-Chen Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Presymptomatic micro RNA targets for treatment of neurodegeneration pathology
    Patent number: 11078535
    Abstract: Compositions and methods are provided for the early detection of neuroinflammation in a patient in a presymptomatic stage of a neurodegenerative disease. The method comprises identifying patients with elevated expression levels of a micro RNA selected from the group consisting of miR142-3p, miR142-5p, miR181a, miR181b, miR219-3p and miR219-5p. The identified patients can then be treated with a therapeutic pharmaceutical composition comprising antimiR oligonucleotides.
    Type: Grant
    Filed: July 7, 2018
    Date of Patent: August 3, 2021
    Assignee: The Trustees of Indiana University
    Inventors: Salil Sharma, Hui-Chen Lu
  • PRESYMPTOMATIC MICRO RNA TARGETS FOR TREATMENT OF NEURODEGENERATION PATHOLOGY
    Publication number: 20200157627
    Abstract: Compositions and methods are provided for the early detection of neuroinflammation in a patient in a presymptomatic stage of a neurodegenerative disease. The method comprises identifying patients with elevated expression levels of a micro RNA selected from the group consisting of miR142-3p, miR142-5p, miR181a, miR181b, miR219-3p and miR219-5p. The identified patients can then be treated with a therapeutic pharmaceutical composition comprising antimiR oligonucleotides.
    Type: Application
    Filed: July 7, 2018
    Publication date: May 21, 2020
    Inventors: Salil Sharma, Hui-Chen Lu