Abstract: Provided are methods and articles of manufacture for use in stem cell therapy, for the treatment of diseases or conditions of SCA. Particularly, the invention provides a method for treating SCA, comprising parenterally or locally administering an effective amount of stem cells as a unit dosage to a subject, wherein the administration is performed with one or more treatment cycles, wherein one treatment cycle comprises dosing three unit dosages each at a dosing interval of two to six weeks.

Abstract: The present disclosure provides a method for treating and/or ameliorating a lung injury or inflammation in the lung, and/or promoting polarization of macrophages in a subject in need thereof, wherein the method comprises administering microRNA-7704 (miR-7704) or a composition comprising miR-7704 to the subject.

Abstract: Provided are methods and articles of manufacture for use in stem cell therapy, for the treatment of diseases or conditions of SCA. Particularly, the invention provides a method for treating SCA, comprising parenterally or locally administering an effective amount of stem cells as a unit dosage to a subject, wherein the administration is performed with one or more treatment cycles, wherein one treatment cycle comprises dosing three unit dosages each at a dosing interval of two to six weeks.

Abstract: The present disclosure provides an exosome composition comprising a population of enriched exosomes. The exosome composition is directly obtained by isolation and ultrafiltration rather than by formulation. The present disclosure also provides a method for producing the exosome composition.

Abstract: Provided are methods and articles of manufacture for use in stem cell therapy, for the treatment of diseases or conditions of SCA. Particularly, the invention provides a method for treating SCA, comprising parenterally or locally administering an effective amount of stem cells as a unit dosage to a subject, wherein the administration is performed with one or more treatment cycles, wherein one treatment cycle comprises dosing three unit dosages each at a dosing interval of two to six weeks.

Abstract: The present disclosure provides a cell culture automation system that provides enclosed culture conditions that may reduce the risk of contamination and automatically culture cells in large scale. Particularly, the cell culture system comprises (i) one or more removable microfluidic microwells and (ii) a culture device holding the microfluidic microwells, wherein each microfluidic microwell has one or multiple hollow units compartmentalized, and containing microfluidic channels with no bottoms throughout the microfluidic microwell, wherein the microfluidic channels contain one or more cell inlets.

Abstract: The invention unexpectedly found that an isolated and modified QPSC population has multi-potentiality, including: osteoblasts (bone cells), chondrocytes (cartilage cells), and adipocytes (fat cells). The QPSC population of the invention features a desirable immunomodulation ability, including inducing, enhancing, or suppressing an immune response and thus has potential value in the prevention and/or treatment of various immune diseases/disorders/conditions. The invention has effective homing ability and regulation ability in complement-dependent cytotoxicity, including the ability to block the activation of host complements and direct migration to the target area and the ability to enhance cell viability, and thus offers better cell protection and therapeutic efficacy in vivo in the prevention and/or treatment of various acute tissue injury, ischemic or degenerative diseases/disorders/conditions.

Abstract: Provided are methods and articles of manufacture for use in stem cell therapy, for the treatment of diseases or conditions of SCA. Particularly, the invention provides a method for treating SCA, comprising parenterally or locally administering an effective amount of stem cells as a unit dosage to a subject, wherein the administration is performed with one or more treatment cycles, wherein one treatment cycle comprises dosing three unit dosages each at a dosing interval of two to six weeks.

Abstract: The invention provides a method of enhancing a directional migration of stem cells, comprising providing one or more stem cell(s) and irradiating the stem cells with an effective energy of green light thereby enhancing stem cell directionally migrating, wherein the orientation of migration of stem cells is opposite to the green light source. Also provided is a stem cell treated by the method of the invention and a device for enhancing a directional migration of stem cells.

Abstract: The invention unexpectedly found that an isolated and modified QPSC population has multi-potentiality, including: osteoblasts (bone cells), chondrocytes (cartilage cells), and adipocytes (fat cells). The QPSC population of the invention features a desirable immunomodulation ability, including inducing, enhancing, or suppressing an immune response and thus has potential value in the prevention and/or treatment of various immune diseases/disorders/conditions. The invention has effective homing ability and regulation ability in complement-dependent cytotoxicity, including the ability to block the activation of host complements and direct migration to the target area and the ability to enhance cell viability, and thus offers better cell protection and therapeutic efficacy in vivo in the prevention and/or treatment of various acute tissue injury, ischemic or degenerative diseases/disorders/conditions.

Abstract: The present invention relates to a cryopreservative device comprising an outer case, one or more layers of space for the cryo-bags, and two or more Teflon cryopreservative bags. The outer case has a cover lip for opening and closing. The Teflon cryopreservative bags are filled with a freezing resistant. In the present invention, the cryo-bags and the Teflon cryopreservative bags are crossly stacked in the cryopreservation device. The Teflon cryopreservative bags are designed to directly contact with the cryo-bags in order to obtain the effect of slow cell freezing.

Abstract: The invention provides a method of enhancing a directional migration of stem cells, comprising providing one or more stem cell(s) and irradiating the stem cells with an effective energy of green light thereby enhancing stem cell directionally migrating, wherein the orientation of migration of stem cells is opposite to the green light source. Also provided is a stem cell treated by the method of the invention and a device for enhancing a directional migration of stem cells.

Abstract: A stator structure includes a main body having multiple frames each having an arc panel, a main tooth, at least one secondary tooth, at least one main coil and at least one secondary coil. The main tooth and the secondary tooth are disposed at one face of the arc panel. The main coil is installed at the main tooth, and the secondary coil is installed at the secondary coil. A rotor is penetrated through the stator structure. The frames are in a multi-layer circular arrangement at the rotor, and a dislocation angle exists between the frame at any layer and the frame at the neighboring layer.

Abstract: An engine device includes an engine, a power generating portion, a motor portion, and a transmission mechanism. The engine includes a piston and a cylinder, and the piston is arranged in the cylinder and moves back and forth between a top dead center and a bottom dead center. The power generating portion and the motor portion are annularly disposed on the periphery of the cylinder. When the piston moves from the top dead center towards the bottom dead center, the transmission mechanism drives a power generating rotor of the power generating portion to move correspondingly in a direction opposite to that of the piston and enables the power generating portion to generate electric power. When the piston is located at the bottom dead center, the motor portion actuates a motor rotor to move, and pushes the piston to move towards the top dead center through the transmission mechanism.

Abstract: The invention relates to a cell population comprising minimal volume of orbital fat-derived stem cells (OFSCs) and its isolation, purification, characterization and application. The OFSCs of the invention are capable of multilineage development and express at least CD90 and CD 105 but not hematopoietic and epithelial markers. The OFSCs have colony formation ability and multi-lineage differentiation ability. They possess at least osteogenic, chondrogenic and adipogenic differentiation capacity; besides mesodermal tri-linage differentiation, the OFSCs have corneal epithelial differentiation potential. Taking together, orbital fat tissues are a novel source for multi-potent stem cells which possess multiple therapeutic potential. Therefore, the OFSCs can be used in cell therapy and tissue engineering.

Abstract: A speed adjusting mechanism for roller traction toroidal continuously variable transmission is disclosed, which comprises an input disk; an output disk coaxially and symmetrically positioned relative to the input disk; a rotation shaft thought the axis of input disk and output disk; a screw rod coaxially connected to the rotation shaft and being rotated accordingly; and a plurality of friction balls respectively contact with the input disk and output disk and rotate same; each friction ball respectively revolved on its own center axis and each center axis respectively connected to a supporting bracket and each supporting bracket respectively connected to an arc-shaped screw gear; wherein the screw rod is engaged to the screw gears so that they will rotate correspondingly to let each center axis tilt to the same extent so that the input disk and out disk will have different rotation rate.

Abstract: An engine device includes an engine, a power generating portion, a motor portion, and a transmission mechanism. The engine includes a piston and a cylinder, and the piston is arranged in the cylinder and moves back and forth between a top dead center and a bottom dead center. The power generating portion and the motor portion are annularly disposed on the periphery of the cylinder. When the piston moves from the top dead center towards the bottom dead center, the transmission mechanism drives a power generating rotor of the power generating portion to move correspondingly in a direction opposite to that of the piston and enables the power generating portion to generate electric power. When the piston is located at the bottom dead center, the motor portion actuates a motor rotor to move, and pushes the piston to move towards the top dead center through the transmission mechanism.

Abstract: A multi-cam electric valve mechanism for engine is disclosed, which comprises: a motor fixed on a cylinder; a motor shaft wherein one side of it connected to the motor and rotated accordingly and the other side of it symmetrically provided with a plurality of rotors whose shafts are perpendicular to the motor shaft; a ring-shaped cam with a plurality of wave-shaped grooves on the circumference thereof corresponding to the rotors and for setting same; a rotation-stopping lever connected to the cylinder and cam respectively to let the cam linearly move along with it; and a valve lever wherein one side of it connected to the cam and the other side of it connected to a valve.

Abstract: An orthotic for correcting a movement of a hip joint of a user includes a support frame, a cam, a leg fixer, a following element and a restoring element. The support frame is attached to the user. The cam is disposed to the support frame. The leg fixer is pivotally connected to the support frame. The following element is moveably mounted on the leg fixer and connected to the cam. The restoring element connected to the leg fixer provides a force of restoring the leg fixer when the leg fixer is moved. When the leg fixer is being moved, a predetermined relative movement between the cam and the following element is produced to correct a movement range of the hip joint.

Abstract: A speed adjusting mechanism for roller traction toroidal continuously variable transmission is disclosed, which comprises an input disk; an output disk coaxially and symmetrically positioned relative to the input disk; a rotation shaft thought the axis of input disk and output disk; a screw rod coaxially connected to the rotation shaft and being rotated accordingly; and a plurality of friction balls respectively contact with the input disk and output disk and rotate same; each friction ball respectively revolved on its own center axis and each center axis respectively connected to a supporting bracket and each supporting bracket respectively connected to an arc-shaped screw gear; wherein the screw rod is engaged to the screw gears so that they will rotate correspondingly to let each center axis tilt to the same extent so that the input disk and out disk will have different rotation rate.