Abstract: A radiofrequency device includes a semiconductor substrate, an inductor structure, a shielding structure, and a mask pattern. The semiconductor substrate includes a first region and a second region. The inductor structure is disposed on the first region of the semiconductor substrate. The shielding structure is disposed on the first region of the semiconductor substrate and located between the inductor structure and the semiconductor substrate in a vertical direction. The mask pattern is disposed on the semiconductor substrate. A first portion of the mask pattern is disposed on the shielding structure and directly contacts the shielding structure, and a top surface of the shielding structure is completely covered by the first portion of the mask pattern.

Abstract: A digital mirroring method includes creating a digital model for each physical device of a plurality of physical devices located in a physical space. Once a related data of each physical device is obtained, the related data of each physical device is mapped to corresponding digital model.

Abstract: The present invention relates to use of an anti-PD-1 antibody in the treatment of a tumor. The present invention also relates to use of a reagent for detecting a gene amplification in the chromosome 11q13 region in a test kit for predicting the therapeutic effect of the anti-PD-1 antibody and/or the antigen-binding fragment thereof on a tumor patient.

Abstract: An antibody or a functional fragment thereof that specifically bind to PD-L1 with high affinity, a nucleic acid molecule that encodes said antibody or the functional fragment thereof, an expression vector and a host cell for use in expressing said antibody or the functional fragment thereof, and a method for producing said antibody or the functional fragment thereof. An immunoconjugate and a pharmaceutical composition containing said antibody or the functional fragment thereof, and a method for using said antibody or the functional fragment thereof to enhance the function of a T cell so as to up-regulate a cell-mediated immune response, for use in treating diseases caused by T cell dysfunction.

Abstract: A system for measurements and calculations of a microcirculatory high-velocity blood flow includes a data acquisition module configured to select and acquire microcirculatory blood vessel image data; a storage module configured to store the acquired microcirculatory blood vessel image data; a velocity measurement module configured to measure a traveling distance and a traveling time of red blood cell (RBC), white blood cell (WBC), or plasma particles in a blood vessel sample and calculate a ratio of the traveling distance to the traveling time to obtain a blood flow velocity; and a high-velocity blood flow index module configured to determine an index level for the microcirculatory high-velocity blood flow. Specifically, an initial threshold, i.e. 1000 ?m/s, for the microcirculatory high-velocity blood flow of sepsis is proposed, which facilitates early diagnosis on sepsis. The changing process of the high-velocity blood flow shows development of the early-stage, intermediate-stage and end-stage sepsis.

Abstract: The present disclosure relates, according to some embodiments, to photostable photoactive compositions comprising (a) at least one photoactive compound that develops within itself an excited state energy when subjected to UV radiation and (b) a block copolymer comprising a plurality of blocks, wherein the block copolymer is operable to quench the excited state energy.

Abstract: An offline mode user account authorization method includes obtaining an access privilege of a user account and setting an offline task access privilege of the user account according to the access privilege, retrieving user account information corresponding to a task to be executed from a preset task information comparison table when the task to be executed is implemented, determining whether the user account is online, executing the task to be executed with a user ID of the user account if the user account is online, and creating a super offline user account and assigning offline task access privilege of the user account to the super offline user account if the user account is not online. The implemented task to be executed is executed with the super offline user account.

Abstract: The present invention provides an image processing circuit for compensating image data for a display panel used for displaying first and second image patterns respectively having first and second current loadings. The image processing circuit is used for: receiving a first original image data of the first image pattern and a second original image data of the second image pattern having the same brightness value for a pixel at the same location; converting the first original image data into a first final image data to compensate for an IR drop according to the first current loading; and converting the second original image data into a second final image data to compensate for the IR drop according to the second current loading. The first final image data and the second final image data have substantially the same brightness value for the pixel at the same location.

Abstract: The present invention provides a highly concentrated liquid formulation comprising an anti-PCSK9 (human proprotein convertase subtilisin/kexin 9) antibody. The formulation further comprises a buffer, a stabilizer and a surfactant. The liquid formulation disclosed has low viscosity, and the antibody is highly stable after several months of storage.

Abstract: A method and device for implementing an FPGA-based large-scale radio frequency interference array correlator are provided. The method includes: obtaining the number of channels of data of a radio frequency interference array, and performing average division; calculating the total correlation of data group and the total correlation between the data group and other data groups respectively through corresponding correlation calculation modules, and performing an accumulation calculation in an integration period to complete the total correlation operation of the radio frequency interference array. By means of grouping division and time division multiplexing, the FPGA resource is effectively utilized, and the calculation process of FPGA is simplified. The new method is suitable for the operation process of the system with high parallelism and high real-time requirements, and provides a high-efficiency solution for the real-time calculation of massive data of the large-scale radio frequency interference array.

Abstract: A digital receiving apparatus includes an analog-to-digital conversion module, a polyphase filter module, a fast Fourier transform module and a phase compensation module, which transforms signals of a target radio source from time domain to frequency domain. It further includes a standard time acquisition module configured to acquire a standard timestamp, a communication module configured to communicate with a host computer, a delay parameter temporary storage module configured to store a to-be-compensated delay parameter, a control enable module configured to generate an enable signal, a delay module configured to perform delay, and a phase parameter generation module configured to temporarily store the to-be-compensated delay parameter and convert it into a phase compensation parameter.

Abstract: The present disclosure relates, according to some embodiments, to photostable photoactive compositions comprising (a) at least one photoactive compound that develops within itself an excited state energy when subjected to UV radiation and (b) a block copolymer comprising a plurality of blocks, wherein the block copolymer is operable to quench the excited state energy.

Abstract: A digital receiving apparatus includes an analog-to-digital conversion module, a polyphase filter module, a fast Fourier transform module and a phase compensation module, which transforms signals of a target radio source from time domain to frequency domain. It further includes a standard time acquisition module configured to acquire a standard timestamp, a communication module configured to communicate with a host computer, a delay parameter temporary storage module configured to store a to-be-compensated delay parameter, a control enable module configured to generate an enable signal, a delay module configured to perform delay, and a phase parameter generation module configured to temporarily store the to-be-compensated delay parameter and convert it into a phase compensation parameter.

Abstract: The present invention relates to an anti-BTLA antibody or an antigen-binding fragment thereof comprising: at least one light chain CDR domain selected from SEQ ID NOs: 7, 8, 9, 10, 11, 12, 16, 17, 18, 22, 23, 24, 31, 32 and 33, and/or at least one heavy chain CDR domain selected from SEQ ID NOs: 1, 2, 3, 4, 5, 6, 13, 14, 15, 19, 20, 21, 25, 26, 27, 28, 29 and 30. The present invention also relates to a nucleic acid molecule encoding the antibody or the antigen-binding fragment thereof, a corresponding expression vector and a host cell, as well as therapeutic use of the antibody or the antigen-binding fragment thereof, the nucleic acid molecule, the expression vector and the host cell.

Abstract: A timing controller and an operation method thereof are provided. The timing controller is used to control a signal timing of a display panel. The timing controller includes an analysis circuit and a decision circuit. The analysis circuit analyzes the content of an image frame to obtain an analysis result. The decision circuit is coupled to the analysis circuit to receive the analysis result. The decision circuit determines a global gray level according to the analysis result. In a blanking interval in which a plurality of sub-pixel circuits of the display panel are turned off, a data voltage corresponding to the global gray level is applied to at least one data line of the display panel corresponding to the sub-pixel circuits.

Abstract: The present disclosure relates, according to some embodiments, to a wearable UV sensor for detecting a dose of an electromagnetic radiation, the wearable UV sensor comprising: (a) a polymer substrate comprising at least one polymer and at least one UV radiation exposure indicator; and (b) an adhesive, wherein exposure of the wearable UV sensor to the dose of the electromagnetic radiation produces a photochromic change in the polymer substrate. The present disclosure also relates to a method for determining a magnitude of a dose of UV radiation exposure, the method comprising: providing a wearable UV sensor comprising a polymer substrate, a UV radiation exposure indicator, and optionally an adhesive layer; exposing the wearable UV sensor to at least one dose of an electromagnetic radiation to form an irradiated wearable UV sensor, wherein the exposing results in a photochromic change by the wearable UV sensor; and determining the magnitude of the at least one dose of electromagnetic radiation.

Abstract: A backlight signal processing method is suitable for a display device including a backlight module and a LCD panel, wherein the number of multiple emitting areas of the backlight module is smaller than the number of multiple pixels of the LCD panel. The backlight signal processing method includes: generating multiple first gray level data signals according to multiple color data signals; grouping the first gray level data signals to calculate multiple second gray level data signals, wherein the number of the second gray level data signals is smaller than the number of the first gray level data signals; multiplying a coefficient matrix to obtain multiple gray level matrices; performing an overlapping operation on the gray level matrices to obtain a backlight matrix; and controlling the emitting areas to display according to the backlight matrix respectively.

Abstract: The present disclosure relates, according to some embodiments, to a method of determining a quantitatively measured photoprotection of a photoprotective composition, the method comprising: (a) distributing the photoprotective composition in a position in between a drawdown bar and at least one substrate to produce a distributed photoprotective composition; (b) drawing down the distributed photoprotective composition to a thickness on at least one substrate to produce a drawn down sample film; (c) drying the drawn down sample film to produce a dried sample film; (d) measuring a UV absorption of the dried sample film to produce a UV absorption spectrum; (e) determining the quantitatively measured photoprotection of the photoprotective composition from the UV absorption spectrum.

Abstract: This invention provides antibodies or functional fragments thereof that bind to PD-1 with high affinity. The invention provides nucleic acid molecules encoding the antibodies or the fragments thereof according to the present invention, expression vectors and host cells for expressing the antibodies or the functional fragments thereof according to the present invention, as well as methods for producing the antibodies or the functional fragments thereof according to the present invention. The present invention also provides immunoconjugates and pharmaceutical compositions comprising the antibodies or the functional fragments thereof according to the present invention. The present invention additionally provides methods for treating a plurality of diseases (comprising cancers, infectious diseases and inflammatory diseases) by using the antibodies or the functional fragments thereof disclosed herein.