Abstract: A pharmaceutical composition for dry powder inhalation is provided, including an active ingredient and a first pharmacologically acceptable excipient. The active ingredient includes sildenafil or a pharmaceutically acceptable salt thereof. The first pharmacologically acceptable excipient includes amino acid, phospholipid, polylactic acid, polylactic acid copolymer, sugar alcohol, or a combination thereof. In some embodiments of the present disclosure, a method of preparing a pharmaceutical composition for dry powder inhalation is further provided. The pharmaceutical composition for dry powder inhalation increases aerosol property meets the requirements for inhalation administration and reduces onset time.

Abstract: A pharmaceutical composition for dry powder inhalation is provided, including an active ingredient and a first pharmacologically acceptable excipient. The active ingredient includes vardenafil or a pharmaceutically acceptable salt thereof. The first pharmacologically acceptable excipient includes amino acid, polysaccharide, phospholipid, polylactic acid, polylactic acid copolymer, or a combination thereof. In some embodiments of the present disclosure, a method of preparing a pharmaceutical composition for dry powder inhalation is further provided.

Abstract: A pharmaceutical composition for dry powder inhalation is provided, including an active ingredient and a first pharmacologically acceptable excipient. The active ingredient includes tadalafil or a pharmaceutically acceptable salt thereof. The first pharmacologically acceptable excipient includes amino acid, polysaccharide, phospholipid, polylactic acid, polylactic acid copolymer, or a combination thereof. In some embodiments of the present disclosure, a method of preparing a pharmaceutical composition for dry powder inhalation is further provided. The pharmaceutical composition for dry powder inhalation increases aerosol property meets the requirements for inhalation administration and reduces onset time.

Abstract: A pharmaceutical composition for dry powder inhalation is provided, including an active ingredient and a first pharmacologically acceptable excipient. The active ingredient includes avanafil or a pharmaceutically acceptable salt thereof. The first pharmacologically acceptable excipient includes amino acid, polysaccharide, phospholipid, polylactic acid, polylactic acid copolymer, or a combination thereof. In some embodiments of the present disclosure, a method of preparing a pharmaceutical composition for dry powder inhalation is further provided. The pharmaceutical composition for dry powder inhalation increases aerosol property, meets the requirements for inhalation administration and reduces onset time.

Abstract: A micro needle holder capable of cutting sutures, configured for holding needles and cutting sutures during microsurgeries, includes a needle holding unit and a suture cutting unit. The needle holding unit includes a pair of first plier bodies and a first shaft, where each of the first plier bodies has a needle holding end, a first shaft connecting part, and a first plier arm. The suture cutting unit includes a pair of second plier bodies and a second shaft, where each of the second plier bodies includes a suture cutting end, a second shaft connecting part, and a second plier arm. Moreover, the first plier arms are respectively connected with the second plier arms and are configured to elastically open and close corporately.

Abstract: A micro-power wind-solar hybrid energy harvesting and power generating device including a solar power generation module, a wind power generation module, a control module, an energy storage module, and an accessory structure are provided. The solar power generation module is mainly composed of a solar thin film cell and a corresponding interface control circuit, and the wind power generation module includes a wind-induced vibration structure, a cantilever beam structure, a piezoelectric element, and a corresponding interface control circuit. The solar thin film cell is mounted at a top of the wind-induced vibration structure, and interface control circuits, the energy storage module, etc. are all arranged inside the wind-induced vibration structure. The control module is configured to handle an energy harvesting and power generating algorithm of the wind-solar hybrid power generating device to maximize the power generation quality and the power generation efficiency of the device.

Abstract: The present invention provides a composition, comprising ferrous amino acid chelate particles sintered from ferrous amino acid chelate, wherein the average particle size of the ferrous amino acid chelate particles ranges from 500 nm to 2600 nm, and the average molecular weight of the particles ranges from 1,500 Dalton to 600,000 Dalton. Besides, the present invention can be used for manufacturing a medicament for treating or ameliorating a pancreas-related disease, wherein the medicament comprises an effective amount of the composition and a pharmaceutically acceptable carrier.

Abstract: An inspiration system related symptom sensing system includes a patch and a processor. The patch includes at least one vibrator and a plurality of receivers. Each of the receivers is configured to generate a reference vibration signal corresponding to the vibrator and a vibration signal corresponding to an inspiration system of an organism. The processor is configured to determine a relative position of each of the receivers related to the inspiration system of the organism based on the reference vibration signals, the vibration signals, and a plurality of positional relationships of the vibrator corresponding to each of the receivers. The processor is configured to generate a spatial position corresponding to the inspiration system and a corresponding symptom type by using a classification model based on the abnormal signals and the relative positions corresponding to the receivers.

Abstract: A pharmaceutical composition for dry powder inhalation includes an active ingredient and a first pharmacologically acceptable excipient. The active ingredient includes bedaquiline or a pharmaceutically acceptable salt thereof. The first pharmacologically acceptable excipient includes amino acid, polysaccharide, phospholipid, polylactic acid, polylactic acid copolymer, or a combination thereof. A method of preparing a pharmaceutical composition for dry powder inhalation is also provided.

Abstract: The present disclosure provides example embodiments relating to conductive features, such as metal contacts, vias, lines, etc., and methods for forming those conductive features. In some embodiments, a structure includes a first dielectric layer over a substrate, a first conductive feature through the first dielectric layer, the first conductive feature comprising a first metal, a second dielectric layer over the first dielectric layer, and a second conductive feature through the second dielectric layer having a lower convex surface extending into the first conductive feature, wherein the lower convex surface of the second conductive feature has a tip end extending laterally under a bottom boundary of the second dielectric layer.

Abstract: A micro-power wind-solar hybrid energy harvesting and power generating device including a solar power generation module, a wind power generation module, a control module, an energy storage module, and an accessory structure are provided. The solar power generation module is mainly composed of a solar thin film cell and a corresponding interface control circuit, and the wind power generation module includes a wind-induced vibration structure, a cantilever beam structure, a piezoelectric element, and a corresponding interface control circuit. The solar thin film cell is mounted at a top of the wind-induced vibration structure, and interface control circuits, the energy storage module, etc. are all arranged inside the wind-induced vibration structure. The control module is configured to handle an energy harvesting and power generating algorithm of the wind-solar hybrid power generating device to maximize the power generation quality and the power generation efficiency of the device.

Abstract: A molybdenum disulfide/graphene/carbon composite material having a hierarchical pore structure includes a composite nanofiber having a diameter of 60 to 500 nm. The composite nanofiber comprises, in mass percentage, 3% to 35% of molybdenum disulfide, 0.2% to 10% of graphene, and 60% to 95% of carbon. The composite nanofiber has a hierarchical pore structure distributed along the axial direction, and has a pore diameter continuously distributed between 0.1 nm and 5 ?m and an average pore diameter between 1.5 nm and 25 nm. On the basis of the pore volume, in the hierarchical pore structure, a micropore structure accounts for 25% to 60%, and a mesoporous structure accounts for 40% to 75%. The microporous structure is distributed on the surface of the nanofiber and the pore wall of the mesoporous structure.

Abstract: Image recognition may include obtaining a first image, segmenting the first image into a plurality of first regions by using a target model, and searching for a target region among bounding boxes in the first image that use points in the first regions as centers. The target region is a bounding box in the first image in which a target object is located. The target model is a pre-trained neural network model configured to recognize from an image, a region in which the target object is located. The target model is obtained through training by using positive samples with a region in which the target object is located marked and negative samples with a region in which a noise is located marked. The target region is marked in the first image to improve accuracy of target object detection in an image.

Abstract: A light-emitting diode (LED) and a manufacturing method thereof are disclosed. The LED includes: a substrate, a light-tight reflective layer, an inner epitaxial layer, an outer epitaxial layer, a non-conducting layer, an ohmic metallic body, a first electrode, and a second electrode. The inner epitaxial layer and the outer epitaxial layer are separated from each other by a separation space. In a view made from a top side of the LED, the separation space forms a closed path and surrounds the light exit hole. The separation space provides an effect of blocking an electrical current and a light emission area in the inner epitaxial layer. By redirecting light emitting from a lateral side of the inner epitaxial layer toward a top side of the LED, the LED shows a low side light ratio.

Abstract: The present invention relates to a variable-flow-path air valve for water hammer prevention and a design method. The variable-flow-path air valve includes a valve body with a top provided with an air intake-exhaust port. A ball valve seat and a floating ball are arranged below the air intake-exhaust port. The valve body is provided with at least one swing check valve configured to be opened inward. The swing check valve includes: a swing valve disc connected to a valve body hinge, a variable-flow-path air inlet controlled by the swing valve disc to open and close, a device for limiting the opening degree of the swing valve disc, and a sealing device. In the present invention, the air valve takes in air through the air intake-exhaust port and the variable flow path, and discharges air only through the air intake-exhaust port.

Abstract: A vacuumizing device includes a vacuum chamber, a bonding fixture and a vacuumizing system. The bonding fixture is disposed in the vacuum chamber and includes a substrate table provided with a plurality of grooves for retention of the substrate by suction. The vacuumizing system is disposed in communication with both the vacuum chamber and grooves. During vacuumizing by the vacuumizing system, a vacuum value in the grooves is smaller than or equal to a vacuum value in the vacuum chamber. In the vacuumizing device and methods, the vacuumizing system is used to vacuumize the grooves in the substrate table and the vacuum chamber so that the vacuum value in the grooves is always smaller than or equal to that in the vacuum chamber. As a result, the substrates are firmly retained on the substrate table without warping, thereby improving the quality of substrate bonding.

Abstract: The present invention relates to a variable-flow-path air valve for water hammer prevention and a design method. The variable-flow-path air valve includes a valve body with a top provided with an air intake-exhaust port. A ball valve seat and a floating ball are arranged below the air intake-exhaust port. The valve body is provided with at least one swing check valve configured to be opened inward. The swing check valve includes: a swing valve disc connected to a valve body hinge, a variable-flow-path air inlet controlled by the swing valve disc to open and close, a device for limiting the opening degree of the swing valve disc, and a sealing device. In the present invention, the air valve takes in air through the air intake-exhaust port and the variable flow path, and discharges air only through the air intake-exhaust port.

Abstract: A micro needle holder capable of cutting sutures, configured for holding needles and cutting sutures during microsurgeries, includes a needle holding unit and a suture cutting unit. The needle holding unit includes a pair of first plier bodies and a first shaft, where each of the first plier bodies has a needle holding end, a first shaft connecting part, and a first plier arm. The suture cutting unit includes a pair of second plier bodies and a second shaft, where each of the second plier bodies includes a suture cutting end, a second shaft connecting part, and a second plier arm. Moreover, the first plier arms are respectively connected with the second plier arms and are configured to elastically open and close corporately.

Abstract: Generally, the present disclosure provides example embodiments relating to conductive features, such as metal contacts, vias, lines, etc., and methods for forming those conductive features. In an embodiment, a structure includes a first dielectric layer over a substrate, a first conductive feature in the first dielectric layer, a second dielectric layer over the first dielectric layer, a second conductive feature in the second dielectric layer, and a blocking region disposed between the first conductive feature and the second conductive feature. The second conductive feature is disposed between and abutting a first sidewall of the second dielectric layer and a second sidewall of the second dielectric layer. The blocking region extends laterally at least from the first sidewall of the second dielectric layer to the second sidewall of the second dielectric layer.

Abstract: A method for fabricating a semiconductor arrangement includes removing a portion of a first dielectric layer to form a first recess defined by sidewalls of the first dielectric layer, forming a first conductive layer in the first recess, removing a portion of the first conductive layer to form a second recess defined by the sidewalls of the first dielectric layer, forming a second conductive layer in the second recess, where the second conductive layer contacts the first conductive layer, forming a second dielectric layer over the second conductive layer, removing a portion of the second dielectric layer to form a third recess defined by sidewalls of the second dielectric layer, where the second conductive layer is exposed through the third recess, and forming a third conductive layer in the third recess, where the third conductive layer contacts the second conductive layer.