Abstract: The present invention provides a detection reagent and therapeutic target for B cell tumor after targeted therapy and related applications. The reagent composition comprises 3 groups of antibodies, with the first group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD24 an antibody, an anti-CD20 antibody, an anti-CD81 antibody, an anti-CD45 antibody; the second group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD20 antibody, an anti-CD72 antibody, an anti-CD45 antibody; and the third group of antibodies including an anti-cytoplasmic CD79a antibody. The reagent composition of the present invention can be applied for the detection of B-lymphocyte tumors after targeted therapy by flow cytometry.

Abstract: At least one computer processor can replace visual words of an unsupervised machine learning classification model with visual objects of an image. At least two co-occurring single visual objects adjacent to each other in pixels of the image can be combined to obtain a compound visual object. The unsupervised machine learning classification model can be augmented to model the image as a mixture of subjects, where each subject is represented through placements of the visual objects in a mixture of concentric spheres centering on a mixture of intersections on a mixture of horizontal layers. At least one processor can learn latent relationships between the placements of the visual objects in a three-dimensional space depicted in the image and image semantics. Learning the latent relationships trains the unsupervised machine learning classification model to perform image subject classification through the placements of the visual objects in a new image.

Abstract: A high-throughput optical sectioning three-dimensional imaging system which includes: a light beam modulation module configured to modulate a light beam into a modulated light beam capable of being focused on a focal plane of an objective lens and being defocused on a defocusing plane of the objective lens; an imaging module configured to employ a camera to image, in different rows of pixels, a sample under illumination of the modulated light beam; a cutting module configured to cut off an imaged surface layer of the sample; a demodulation module configured to demodulate a sample image of one sample strip of one surface layer into an optical sectioning image, and reconstruct the optical sectioning image of each sample strip of each surface layer into a three-dimensional image. The present disclosure achieves imaging of a whole sample by dividing the sample into at least one surface layer, dividing the at least one surface layer into at least one sample strip, and imaging each sample strip.

Abstract: A high-throughput optical sectioning imaging method and imaging system. The method includes: modulating a light beam into a modulated light beam capable of being focused on a focal plane of an objective lens and being defocused on a defocusing plane of the objective lens, the modulated light beam having incompletely identical modulated intensities on the focal plane of the objective lens; imaging, in different rows of pixels, a sample under illumination of the modulated light beam to obtain sample images in the different rows of pixels; obtaining focal plane images of sample images in the different rows of pixels by demodulation of the sample images according to a demodulation algorithm. The system includes a light beam modulation module, an imaging module and a demodulation module.

Abstract: The invention discloses an atomic fluorescence analysis method and device using water as a carrier fluid, belonging to the atomic fluorescence analysis in the field of analytical chemistry; the method is to replace hydrochloric acid and a reducing agent with water as the carrier fluid in the conventional sampling and fluid delivery process to carry the test liquid and reagent into the reactor to complete a reaction. The invention effectively overcomes the memory effect by using water as the carrier fluid and improves the determination sensitivity and accuracy, which saves a large amount of high-purity hydrochloric acid and reducing agent at the same time, greatly reducing the analysis cost, and significantly improving the operating environment, which is the innovation of atomic fluorescence analysis technology.

Abstract: A vehicle USB Type-C connector, comprising a cable end member and a board end member engaged together; the CPA is inserted into the engagement groove; the PCB attached male head has an end protruding from a cavity opening on one end of the cable end plastic shell cavity; the encapsulated outer mold is inserted into a cavity opening on another end of the cable end plastic shell cavity; the encapsulated outer mold has an engagement side on two sides thereof and inserted into the lateral engagement groove; the upper lock plate is engaged above the engagement groove, the lower lock plate is inserted into the engagement groove, and the CPA is fastened with the cable end member. The present invention reduces the on-board height and strengthens the liability after engagement.

Abstract: A vehicle USB Type-C connector, comprising a cable end member and a board end member engaged together; the CPA is inserted into the engagement groove; the PCB attached male head has an end protruding from a cavity opening on one end of the cable end plastic shell cavity; the encapsulated outer mold is inserted into a cavity opening on another end of the cable end plastic shell cavity; the encapsulated outer mold has an engagement side on two sides thereof and inserted into the lateral engagement groove; the upper lock plate is engaged above the engagement groove, the lower lock plate is inserted into the engagement groove, and the CPA is fastened with the cable end member. The present invention reduces the on-board height and strengthens the liability after engagement.

Abstract: The disclosure relates to the technical field of medicine and in particular to a polyethylene glycol conjugated drug of formula I or a pharmaceutically acceptable salt thereof. The disclosure further relates to a method for preparation and an intermediate of the polyethylene glycol conjugated drug or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugated drug or a pharmaceutically acceptable salt thereof, and use of the polyethylene glycol conjugated drug or a pharmaceutically acceptable salt thereof in preparation of a medicament.

Abstract: The invention discloses an atomic fluorescence analysis method and device using water as a carrier fluid, belonging to the atomic fluorescence analysis in the field of analytical chemistry; the method is to replace hydrochloric acid and a reducing agent with water as the carrier fluid in the conventional sampling and fluid delivery process to carry the test liquid and reagent into the reactor to complete a reaction. The invention effectively overcomes the memory effect by using water as the carrier fluid and improves the determination sensitivity and accuracy, which saves a large amount of high-purity hydrochloric acid and reducing agent at the same time, greatly reducing the analysis cost, and significantly improving the operating environment, which is the innovation of atomic fluorescence analysis technology.

Abstract: A high-throughput optical sectioning three-dimensional imaging system which includes: a light beam modulation module configured to modulate a light beam into a modulated light beam capable of being focused on a focal plane of an objective lens and being defocused on a defocusing plane of the objective lens; an imaging module configured to employ a camera to image, in different rows of pixels, a sample under illumination of the modulated light beam; a cutting module configured to cut off an imaged surface layer of the sample; a demodulation module configured to demodulate a sample image of one sample strip of one surface layer into an optical sectioning image, and reconstruct the optical sectioning image of each sample strip of each surface layer into a three-dimensional image. The present disclosure achieves imaging of a whole sample by dividing the sample into at least one surface layer, dividing the at least one surface layer into at least one sample strip, and imaging each sample strip.

Abstract: A high-throughput optical sectioning imaging method and imaging system. The method includes: modulating a light beam into a modulated light beam capable of being focused on a focal plane of an objective lens and being defocused on a defocusing plane of the objective lens, the modulated light beam having incompletely identical modulated intensities on the focal plane of the objective lens; imaging, in different rows of pixels, a sample under illumination of the modulated light beam to obtain sample images in the different rows of pixels; obtaining focal plane images of sample images in the different rows of pixels by demodulation of the sample images according to a demodulation algorithm. The system includes a light beam modulation module, an imaging module and a demodulation module.

Abstract: A method and apparatus for acquiring people flow information, and a method and apparatus for processing people flow information are provided.

Abstract: Disclosed are systems and methods for acquiring height of a stereo camera, applied to the stereo camera. An example method includes acquiring angle information of a stereo camera, with the angle information including a pitch angle and a tilt angle. A ground image of a scenario where the stereo camera is deployed is captured and depth information of each pixel on the ground image is determined. A three-dimensional point set based on depth information of each pixel on the ground image is established, with the three-dimensional point set including coordinate information of each three-dimensional point corresponding to each pixel of the ground image. Height of the stereo camera is determined based on the angle information and the three-dimensional point set.

Abstract: Embodiments of application discloses a method and device for determining external parameters of a stereo camera. The method comprises: acquiring ground surface data of a location of the stereo camera; generating, according to three-dimensional coordinates of each pixel in the ground surface data in a camera coordinate system corresponding to the stereo camera, a first plane equation in the camera coordinate system that conforms to the three-dimensional coordinates of the pixels; determining, according to a distance between the origin of the camera coordinate system and the ground surface, a setting height of the stereo camera; and generating, according to the first plane equation, a plane normal vector corresponding to the first plane equation; and determining, according to the plane normal vector, a pitch angle of the stereo camera and an inclination angle of the stereo camera. The external parameters of the stereo camera can be determined without using a reference point in a scene.

Abstract: Fast channel deployment is achieved amongst subscriber devices (SDs) having an incident scene role at an incident scene. An SD detects an incident scene arrival trigger associated with arrival at an incident scene. Responsive to detecting the incident scene arrival trigger, the SD (i) tunes to a pre-configured incident channel or (ii) scans a plurality of channels for an incident channel and tunes to the incident channel once located. The SD receives, via the incident channel, an incident scene role to traffic channel mapping that maps a particular incident scene role associated with the subscriber device to a particular assigned traffic channel on which subscriber devices associated with a same incident scene role may communicate. The SD tunes to the particular assigned traffic channel as a function of the incident scene role to traffic channel mapping.

Abstract: An electrical connector mounted on a PCB includes: an housing comprising a base, a mating tongue and a mounting portion, each surface of the mating tongue defining twelve terminal positions (P1) through (P12); two rows of terminals, each terminal including a mating portion, a leg portion and a middle portion connecting with the mating portion and the leg portion, each leg portion defining a soldering pad. Each row of terminals include grounding terminals in terminal positions (P1, P12) power terminals in terminal positions (P4, P9), and there are no terminals set in terminal positions (P2, P3, P10, P11). The soldering pads of the two rows of terminals are arranged in one row and at least two grounding terminals or two power terminals aligned with each other in a vertical direction are located side by side so as to share a same pad defined on the PCB.

Abstract: Disclosed are systems and methods for acquiring height of a stereo camera, applied to the stereo camera. An example method includes acquiring angle information of a stereo camera, with the angle information including a pitch angle and a tilt angle. A ground image of a scenario where the stereo camera is deployed is captured and depth information of each pixel on the ground image is determined. A three-dimensional point set based on depth information of each pixel on the ground image is established, with the three-dimensional point set including coordinate information of each three-dimensional point corresponding to each pixel of the ground image. Height of the stereo camera is determined based on the angle information and the three-dimensional point set.

Abstract: Embodiments of application discloses a method and device for determining external parameters of a stereo camera. The method comprises: acquiring ground surface data of a location of the stereo camera; generating, according to three-dimensional coordinates of each pixel in the ground surface data in a camera coordinate system corresponding to the stereo camera, a first plane equation in the camera coordinate system that conforms to the three-dimensional coordinates of the pixels; determining, according to a distance between the origin of the camera coordinate system and the ground surface, a setting height of the stereo camera; and generating, according to the first plane equation, a plane normal vector corresponding to the first plane equation; and determining, according to the plane normal vector, a pitch angle of the stereo camera and an inclination angle of the stereo camera. The external parameters of the stereo camera can be determined without using a reference point in a scene.

Abstract: A method for automatically altering an imaging area in microscopic imaging of a biological sample. In the method, a sample outline is differentiated from surrounding tissues by means of endogenous or exogenous markers; an initial sample imaging area is set; optical microscopic imaging is performed on a sample surface layer, wherein the imaging area is larger than an area to be imaged of the sample; an actual sample area is calculated by an outline identification algorithm using an imaging result of the sample surface layer and is set as an imaging area of next layer; optical microscopic imaging is performed on a sample to be imaged of the next layer according to the set imaging area, wherein the imaging area covers the area to be imaged of the sample and no redundant imaging is performed; and the above steps are repeated until a data acquisition task is completed.